{"id":99511,"date":"2026-02-15T00:15:57","date_gmt":"2026-02-14T23:15:57","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=99511"},"modified":"2026-02-14T15:06:44","modified_gmt":"2026-02-14T14:06:44","slug":"leky-na-hubnuti-podvyziva-nedostatek-vitaminu-a-kurdeje","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2026\/02\/15\/leky-na-hubnuti-podvyziva-nedostatek-vitaminu-a-kurdeje\/","title":{"rendered":"L\u00e9ky na hubnut\u00ed: Podv\u00fd\u017eiva, nedostatek vitam\u00edn\u016f a kurd\u011bje"},"content":{"rendered":"
<\/div>\n

Takzvan\u00e9 l\u00e9ky s GLP-1 se st\u00e1le \u010dast\u011bji pou\u017e\u00edvaj\u00ed k boji proti obezit\u011b. Jsou lidem prezentov\u00e1ny jako \u201ebezpe\u010dn\u00e9 a \u00fa\u010dinn\u00e9\u201c. Ale jsou skute\u010dn\u011b bezpe\u010dn\u00e9? Nov\u00e1 studie vyvol\u00e1v\u00e1 v\u00e1\u017en\u00e9 ot\u00e1zky.<\/span><\/strong><\/p>\n

V sou\u010dasn\u00e9 dob\u011b je v N\u011bmecku pova\u017eov\u00e1no za ob\u00e9zn\u00edch p\u0159ibli\u017en\u011b 18 procent mu\u017e\u016f a 13 procent \u017een. V Rakousku je to pr\u016fm\u011brn\u011b asi 17 procent dosp\u011bl\u00e9 populace a ve \u0160v\u00fdcarsku asi 12 procent v\u0161ech lid\u00ed ve v\u011bku 15 let a star\u0161\u00edch. V\u00edce ne\u017e polovina N\u011bmc\u016f, stejn\u011b jako zhruba t\u0159etina Raku\u0161an\u016f a \u0160v\u00fdcar\u016f, je obecn\u011b pova\u017eov\u00e1na za osoby s nadv\u00e1hou. To jsou skute\u010dn\u011b z\u00e1va\u017en\u00e1 \u010d\u00edsla.<\/span><\/p>\n

To v\u0161ak s sebou nese i zna\u010dn\u00e1 zdravotn\u00ed rizika \u2013 od kardiovaskul\u00e1rn\u00edch onemocn\u011bn\u00ed a\u017e po cukrovku. \u010casto s t\u00edm jsou spojeny i psychologick\u00e9 probl\u00e9my, jako je n\u00edzk\u00e9 sebev\u011bdom\u00ed. Nen\u00ed proto divu, \u017ee st\u00e1le v\u00edce lid\u00ed d\u00e1v\u00e1 p\u0159ednost l\u00e9k\u016fm na hubnut\u00ed, kter\u00e9 slibuj\u00ed rychl\u00e9 sn\u00ed\u017een\u00ed hmotnosti, ne\u017e aby se vydali n\u00e1ro\u010dnou cestou zm\u011bn stravy a zv\u00fd\u0161en\u00e9ho pohybu.<\/span><\/p>\n

Tyto takzvan\u00e9 l\u00e9ky s GLP-1, oslavovan\u00e9 jako pr\u016flom v l\u00e9\u010db\u011b obezity, v\u0161ak podle ned\u00e1vn\u00e9 studie p\u0159ich\u00e1zej\u00ed s n\u011bkter\u00fdmi v\u00fdznamn\u00fdmi potenci\u00e1ln\u00edmi komplikacemi. Ned\u00e1vno publikovan\u00e1 studie spojuje tyto l\u00e9ky s podv\u00fd\u017eivou, nedostatkem vitam\u00edn\u016f a v extr\u00e9mn\u00edch p\u0159\u00edpadech s nemocemi, jako jsou kurd\u011bje a nevratn\u00e9 po\u0161kozen\u00ed mozku.<\/span><\/p>\n

Studie, kterou v \u010dasopise Obesity Reviews publikovali \u0161v\u00e9d\u0161t\u00ed a austral\u0161t\u00ed v\u011bdci pod n\u00e1zvem \u201e\u00a0<\/span>Systematick\u00fd p\u0159ehled identifikuj\u00edc\u00ed kritick\u00e9 mezery v d\u016fkazech p\u0159i hl\u00e1\u0161en\u00ed zm\u011bn ve strav\u011b v randomizovan\u00fdch kontrolovan\u00fdch studi\u00edch p\u0159edepisuj\u00edc\u00edch liraglutid, semaglutid nebo tirzepatid<\/span><\/a> \u201c, vyvol\u00e1v\u00e1 v\u00e1\u017en\u00e9 ot\u00e1zky t\u00fdkaj\u00edc\u00ed se bezpe\u010dnosti zdrav\u00ed pacient\u016f.<\/span><\/p>\n

L\u00e9ky s GLP-1, v\u010detn\u011b p\u0159\u00edpravk\u016f Saxenda, Wegovy, Mounjaro a Ozempic, mohou pomoci p\u0159i hubnut\u00ed. Studie je v\u0161ak tak\u00e9 spojuj\u00ed se z\u00e1va\u017en\u00fdmi vedlej\u0161\u00edmi \u00fa\u010dinky. Pat\u0159\u00ed mezi n\u011b gastrointestin\u00e1ln\u00ed probl\u00e9my, akutn\u00ed pankreatitida, vy\u0161\u0161\u00ed v\u00fdskyt onemocn\u011bn\u00ed \u017elu\u010dn\u00edku a \u017elu\u010dov\u00fdch cest, ledvinov\u00e9 kameny, artritida, poruchy sp\u00e1nku, zubn\u00ed kaz, vypad\u00e1v\u00e1n\u00ed vlas\u016f a \u00fabytek kostn\u00ed hustoty a svalov\u00e9 hmoty. L\u00e9ky mohou b\u00fdt tak\u00e9 spojeny s rakovinou.<\/span><\/p>\n

Nov\u00fd p\u0159ehledov\u00fd \u010dl\u00e1nek o podv\u00fd\u017eiv\u011b a l\u00e9c\u00edch s obsahem GLP-1 navazuje na\u00a0<\/span>n\u00e1zorov\u00fd \u010dl\u00e1nek britsk\u00e9 praktick\u00e9 l\u00e9ka\u0159ky Dr. Ellen Fallowsov\u00e9 publikovan\u00fd v \u010dervenci v \u010dasopise The BMJ<\/span><\/a>\u00a0. Poznamenala, \u017ee v\u011bt\u0161ina studi\u00ed o t\u011bchto l\u00e9c\u00edch nezkoum\u00e1 mo\u017en\u00e9 souvislosti se z\u00e1va\u017en\u00fdmi komplikacemi souvisej\u00edc\u00edmi s v\u00fd\u017eivou.<\/span><\/p>\n

Mezi zn\u00e1m\u00e9 komplikace pat\u0159\u00ed z\u00e1va\u017en\u00fd nedostatek thiaminu (vitaminu B1), kter\u00fd m\u016f\u017ee vyvolat Wernickeho encefalopatii a v\u00e9st k nevratn\u00e9 demenci. Byly tak\u00e9 hl\u00e1\u0161eny p\u0159\u00edpady metabolick\u00e9 acid\u00f3zy spojen\u00e9 s extr\u00e9mn\u00edm potla\u010den\u00edm chuti k j\u00eddlu a kriticky n\u00edzkou hladinou ho\u0159\u010d\u00edku. Pouh\u00e9 spol\u00e9h\u00e1n\u00ed se na l\u00e9ky na hubnut\u00ed a sni\u017eov\u00e1n\u00ed kalori\u00ed by mohlo nakonec v\u00e9st k v\u011bt\u0161\u00edm zdravotn\u00edm probl\u00e9m\u016fm ne\u017e samotn\u00e1 nadv\u00e1ha. Tato studie zkoumala 41 randomizovan\u00fdch kontrolovan\u00fdch studi\u00ed t\u011bchto l\u00e9k\u016f proveden\u00fdch v posledn\u00edch 17 letech, kter\u00fdch se z\u00fa\u010dastnilo v\u00edce ne\u017e 50 000 \u00fa\u010dastn\u00edk\u016f.<\/span><\/p>\n

Pouze dv\u011b studie zaznamenaly jako v\u00fdsledek zm\u011bny v p\u0159\u00edjmu potravy a jedna z t\u011bchto studi\u00ed nebyla publikov\u00e1na. Ob\u011b zjistily, \u017ee jedinci u\u017e\u00edvaj\u00edc\u00ed l\u00e9k sn\u00ed\u017eili sv\u016fj celkov\u00fd p\u0159\u00edjem energie. L\u00e9k d\u00e1le zm\u011bnil rozlo\u017een\u00ed tuk\u016f, b\u00edlkovin a sacharid\u016f v konzumovan\u00e9 potrav\u011b. Auto\u0159i hodnotili kvalitu obou studi\u00ed jako \u201e\u0161patnou\u201c a \u201ep\u0159ijatelnou\u201c. \u201eTato zji\u0161t\u011bn\u00ed poukazuj\u00ed na z\u00e1sadn\u00ed mezeru v literatu\u0159e,\u201c uzav\u0159eli.<\/span><\/p>\n

Jedn\u00edm z probl\u00e9m\u016f je kvalita j\u00eddla. Kl\u00ed\u010dem k \u00fasp\u011bchu nen\u00ed j\u00edst m\u00e9n\u011b \u2013 sp\u00ed\u0161e je nutn\u00e9 to (i s l\u00e9ky) kombinovat s vyv\u00e1\u017eenou a zdravou stravou. Mnoho lid\u00ed s obezitou se ji\u017e spol\u00e9h\u00e1 na levn\u00e9, energeticky hust\u00e9, ale na \u017eiviny chud\u00e9 potraviny. Siln\u00e9 l\u00e9ky mohou v\u00fdrazn\u011b sni\u017eovat chu\u0165 k j\u00eddlu. I kdy\u017e to m\u016f\u017ee sn\u00ed\u017eit celkov\u00fd p\u0159\u00edjem kalori\u00ed, m\u016f\u017ee to tak\u00e9 drasticky sn\u00ed\u017eit vst\u0159eb\u00e1v\u00e1n\u00ed esenci\u00e1ln\u00edch vitam\u00edn\u016f, miner\u00e1l\u016f a b\u00edlkovin.<\/span><\/p>\n

Nakonec takov\u00e9 l\u00e9ky skute\u010dn\u011b vedou k \u00fabytku hmotnosti, \u010d\u00e1ste\u010dn\u011b potla\u010den\u00edm chuti k j\u00eddlu \u2013 ale bez sou\u010dasn\u00e9 \u00fapravy stravovac\u00edch n\u00e1vyk\u016f jsou pravd\u011bpodobn\u00e9 v\u00e1\u017en\u00e9 zdravotn\u00ed probl\u00e9my.<\/span><\/p>\n

\"\"<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Takzvan\u00e9 l\u00e9ky s GLP-1 se st\u00e1le \u010dast\u011bji pou\u017e\u00edvaj\u00ed k boji proti obezit\u011b. Jsou lidem prezentov\u00e1ny…<\/p>\n","protected":false},"author":2,"featured_media":99512,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[6220,1503,1020,7073],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/99511"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=99511"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/99511\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/99512"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=99511"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=99511"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=99511"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}