{"id":98275,"date":"2026-01-31T00:32:16","date_gmt":"2026-01-30T23:32:16","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=98275"},"modified":"2026-01-30T15:15:38","modified_gmt":"2026-01-30T14:15:38","slug":"pfizerova-bezchybna-genova-injekce-promotory-rakoviny-z-laboratore","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2026\/01\/31\/pfizerova-bezchybna-genova-injekce-promotory-rakoviny-z-laboratore\/","title":{"rendered":"Pfizerova bezchybn\u00e1 genov\u00e1 injekce? Promotory rakoviny z laborato\u0159e"},"content":{"rendered":"
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Studie kanadsk\u00fdch v\u011bdc\u016f zve\u0159ejn\u011bn\u00e1 na PubMed v prosinci 2025 ukazuje, \u017ee injekce genu mRNA od spole\u010dnost\u00ed Pfizer\/BioNTech obsahuje zbytky promotoru SV40, genetick\u00e9ho p\u0159ep\u00edna\u010de pou\u017e\u00edvan\u00e9ho ve v\u00fdzkumu rakoviny ke specifick\u00e9mu spu\u0161t\u011bn\u00ed n\u00e1dor\u016f u laboratorn\u00edch my\u0161\u00ed.<\/span><\/strong><\/p>\n

Studie Davida J. Speichera a koleg\u016f analyzovala p\u016fvodn\u00ed \u0161ar\u017ee vakc\u00edn Pfizer\/BioNTech a Moderna. Pomoc\u00ed p\u0159esn\u00fdch metod\u00a0<\/span>,<\/span><\/a> jako je fluorometrie a qPCR, v\u011bdci kvantifikovali zbytkovou plazmidovou DNA, tedy zbytky bakteri\u00e1ln\u00edho produk\u010dn\u00edho procesu, kter\u00e9 by v ide\u00e1ln\u00edm p\u0159\u00edpad\u011b m\u011bly b\u00fdt z velk\u00e9 \u010d\u00e1sti odstran\u011bny. V d\u00e1vk\u00e1ch Pfizeru dosahovaly hodnoty a\u017e 1 548 ng DNA na d\u00e1vku, konkr\u00e9tn\u011b zesilova\u010d promotoru SV40, a to a\u017e 23,72 ng. Moderna vykazovala v\u00fdrazn\u011b ni\u017e\u0161\u00ed hladiny, ale v p\u0159\u00edpad\u011b Pfizeru dv\u011b ze \u0161esti testovan\u00fdch \u0161ar\u017e\u00ed dokonce p\u0159ekro\u010dily ji\u017e tak m\u00edrn\u00e9 limity FDA a WHO pro oblast SV40.<\/span><\/p>\n

Spole\u010dnost Pfizer\/BioNTech pou\u017e\u00edv\u00e1 plazmidy jako templ\u00e1ty pro transkripci mRNA p\u0159i komer\u010dn\u00ed v\u00fdrob\u011b sv\u00fdch injek\u010dn\u00edch p\u0159\u00edpravk\u016f pro editaci gen\u016f. Tyto plazmidy obsahuj\u00ed promotor SV40, siln\u00fd aktiv\u00e1tor z opi\u010d\u00edho viru 40, kter\u00fd s extr\u00e9mn\u00ed \u00fa\u010dinnost\u00ed \u0159\u00edd\u00ed genovou expresi v sav\u010d\u00edch bu\u0148k\u00e1ch. V klinick\u00e9 f\u00e1zi byl pou\u017eit jin\u00fd postup, ale tato metoda byla p\u0159ijata pro masov\u00fd trh a zjevn\u011b nebylo dosa\u017eeno \u00fapln\u00e9ho odstran\u011bn\u00ed fragment\u016f DNA. Fragmenty jsou mal\u00e9 a zapouzd\u0159en\u00e9 v lipidov\u00fdch nano\u010d\u00e1stic\u00edch speci\u00e1ln\u011b navr\u017een\u00fdch tak, aby pronikaly bun\u011b\u010dn\u00fdmi membr\u00e1nami a transportovaly obsah do j\u00e1dra.<\/span><\/p>\n

Ve v\u00fdzkumu rakoviny se promotor SV40 pou\u017e\u00edv\u00e1 ji\u017e po desetilet\u00ed k vytvo\u0159en\u00ed transgenn\u00edch my\u0161\u00ed, kter\u00e9 spolehliv\u011b vyv\u00edjej\u00ed n\u00e1dory. Jeho velk\u00fd virov\u00fd T antigen deaktivuje tumorov\u00e9 supresory, jako jsou p53 a Rb, a t\u00edm zabra\u0148uje potla\u010den\u00ed rakoviny, co\u017e je standardn\u00ed model pro n\u00e1dory prostaty, mozku nebo slinivky b\u0159i\u0161n\u00ed. Ka\u017ed\u00fd, kdo si prostuduje onkologickou literaturu, zjist\u00ed, \u017ee toto uplatn\u011bn\u00ed je v\u0161udyp\u0159\u00edtomn\u00e9. Promotor \u0159\u00edd\u00ed expresi onkogenn\u00edch gen\u016f u my\u0161\u00ed tak efektivn\u011b, \u017ee si ho v\u011bdci vyb\u00edraj\u00ed jako n\u00e1stroj pro studium v\u00fdvoje rakoviny a jej\u00edch potenci\u00e1ln\u00edch terapi\u00ed. Z tohoto d\u016fvodu se SV40 po desetilet\u00ed\u00a0<\/span>nepou\u017e\u00edval<\/span><\/a> p\u0159i v\u00fdrob\u011b vakc\u00edn . A\u017e dosud.<\/span><\/p>\n

Pou\u017eit\u00ed SV40 p\u0159i v\u00fdrob\u011b injekc\u00ed genu mRNA lze jen st\u011b\u017e\u00ed vysv\u011btlit pouhou nedbalost\u00ed. Auto\u0159i studie hovo\u0159\u00ed o \u201ev\u00fdznamn\u00fdch bezpe\u010dnostn\u00edch obav\u00e1ch\u201c a poukazuj\u00ed na zv\u00fd\u0161enou m\u00edru transfekce (zaveden\u00ed ciz\u00ed DNA a RNA) lipidov\u00fdmi nano\u010d\u00e1sticemi, stejn\u011b jako na kumulativn\u00ed \u00fa\u010dinky opakovan\u00e9ho o\u010dkov\u00e1n\u00ed. Potenci\u00e1ln\u00ed integrace do lidsk\u00e9ho genomu, z\u00e1n\u011btliv\u00e9 reakce (autoimunitn\u00ed onemocn\u011bn\u00ed) nebo dlouhodob\u00e1 onkogenn\u00ed rizika \u2013 to v\u0161e z\u016fstalo neprozkouman\u00e9 a nezohledn\u011bn\u00e9. Navzdory tomu vl\u00e1dn\u00ed regula\u010dn\u00ed agentury, jako jsou EMA a FDA, schv\u00e1lily injekce genu mRNA, p\u0159esto\u017ee d\u0159\u00edv\u011bj\u0161\u00ed anal\u00fdzy Kevina McKernana a dal\u0161\u00edch ji\u017e nazna\u010dovaly podobnou kontaminaci.<\/span><\/p>\n

Jak se mohla l\u00e1tka pou\u017e\u00edvan\u00e1 v laborato\u0159\u00edch k \u00famysln\u00e9mu vyvol\u00e1n\u00ed rakoviny dostat do produktu, kter\u00fd je prod\u00e1v\u00e1n jako \u201ebezpe\u010dn\u00fd a \u00fa\u010dinn\u00fd\u201c? Odpov\u011bdn\u00ed osoby ve spole\u010dnostech Pfizer\/BioNTech a \u00fa\u0159ady z\u016fst\u00e1vaj\u00ed ml\u010denliv\u00e9. Studie z Ontaria je dal\u0161\u00edm d\u016fkazem toho, \u017ee bezpe\u010dnost pacient\u016f nebyla b\u011bhem pandemie prioritou.<\/span><\/p>\n

Pacienti jsou samoz\u0159ejm\u011b nemocn\u00ed lid\u00e9. Genovou injekc\u00ed byli \u201el\u00e9\u010deni\u201c v\u0161ichni \u2013 d\u011bti, zdrav\u00ed lid\u00e9 i ti s \u201easymptomatick\u00fdmi onemocn\u011bn\u00edmi\u201c. Zdrav\u00ed lid\u00e9 byli zbyte\u010dn\u011b experimentov\u00e1ni s l\u00e1tkami, jejich\u017e dlouhodob\u00e9 n\u00e1sledky nikdo nedok\u00e1\u017ee p\u0159edv\u00eddat. To v\u0161e pod rou\u0161kou ochrany ve\u0159ejn\u00e9ho zdrav\u00ed. Farmaceutick\u00fd pr\u016fmysl z toho profitoval, jeho\u017e zisky dos\u00e1hly astronomick\u00fdch v\u00fd\u0161ek. Stejn\u011b tak politici, jejich\u017e moc nesm\u00edrn\u011b rostla a kte\u0159\u00ed byli s farmaceutick\u00fdm pr\u016fmyslem propojeni. A m\u00e9dia, kter\u00e1 od vl\u00e1dy a farmaceutick\u00e9ho pr\u016fmyslu dost\u00e1vala stovky milion\u016f na prosazov\u00e1n\u00ed \u201eplandemick\u00e9ho\u201c narativu.<\/span><\/p>\n

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Studie kanadsk\u00fdch v\u011bdc\u016f zve\u0159ejn\u011bn\u00e1 na PubMed v prosinci 2025 ukazuje, \u017ee injekce genu mRNA od…<\/p>\n","protected":false},"author":2,"featured_media":98276,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[1042,895,694,315,1366,46],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/98275"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=98275"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/98275\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/98276"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=98275"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=98275"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=98275"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}