{"id":97454,"date":"2026-01-22T00:21:30","date_gmt":"2026-01-21T23:21:30","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=97454"},"modified":"2026-01-21T12:11:00","modified_gmt":"2026-01-21T11:11:00","slug":"studie-odhaluje-americky-zakon-o-biologicke-bezpecnosti-umoznuje-legalni-rekonstrukci-viru-spanelske-chripky-z-roku-1918","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2026\/01\/22\/studie-odhaluje-americky-zakon-o-biologicke-bezpecnosti-umoznuje-legalni-rekonstrukci-viru-spanelske-chripky-z-roku-1918\/","title":{"rendered":"Studie odhaluje: Americk\u00fd z\u00e1kon o biologick\u00e9 bezpe\u010dnosti umo\u017e\u0148uje leg\u00e1ln\u00ed rekonstrukci viru \u0161pan\u011blsk\u00e9 ch\u0159ipky z roku 1918"},"content":{"rendered":"
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\u201eKritick\u00e1 mezera\u201c v americk\u00fdch pravidlech biologick\u00e9 bezpe\u010dnosti umo\u017e\u0148uje leg\u00e1ln\u00ed sestaven\u00ed DNA viru \u0161pan\u011blsk\u00e9 ch\u0159ipky z roku 1918.<\/span><\/strong><\/p>\n

\u201eV r\u00e1mci tohoto chybn\u00e9ho syst\u00e9mu nemaj\u00ed poskytovatel\u00e9 \u017e\u00e1dnou z\u00e1konnou povinnost monitorovat nebo omezovat p\u0159\u00edstup,\u201c potvrzuj\u00ed v\u00fdzkumn\u00edci z MIT.<\/span><\/p>\n

Nov\u00e1 recenzovan\u00e1 studie publikovan\u00e1<\/a>\u00a0ve \u010dtvrtek v\u00a0<\/span>\u010dasopise Nature Communications<\/span><\/em><\/a>\u00a0dokumentuje, jak sou\u010dasn\u00e9 americk\u00e9 p\u0159edpisy o biologick\u00e9 bezpe\u010dnosti umo\u017e\u0148uj\u00ed jednotlivc\u016fm leg\u00e1ln\u011b z\u00edskat \u00fadajn\u00fd genetick\u00fd materi\u00e1l pro rekonstrukci viru ch\u0159ipky z roku 1918 n\u00e1kupem neregulovan\u00fdch fragment\u016f DNA od komer\u010dn\u00edch prodejc\u016f \u2013 ani\u017e by to vyvolalo feder\u00e1ln\u00ed dohled nebo z\u00e1sah org\u00e1n\u016f \u010dinn\u00fdch v trestn\u00edm \u0159\u00edzen\u00ed.<\/span><\/p>\n

Abstrakt studie zn\u00ed:<\/span><\/p>\n

\u201eAmerick\u00e9 p\u0159edpisy t\u00fdkaj\u00edc\u00ed se tzv.\u00a0<\/span>selektovan\u00fdch agens<\/span>\u00a0ignoruj\u00ed snadno sestaviteln\u00e9 fragmenty DNA, co\u017e \u010din\u00ed screeningov\u00e9 postupy ne\u00fa\u010dinn\u00fdmi p\u0159i synt\u00e9ze bez ohledu na jejich p\u0159esnost. Z\u00edskali jsme neregulovanou DNA, kter\u00e1 by dohromady sta\u010dila k tomu, aby zku\u0161en\u00fd \u010dlov\u011bk vytvo\u0159il virus ch\u0159ipky z roku 1918 od des\u00edtek dodavatel\u016f, co\u017e dokazuje, \u017ee fragmenty\u00a0mus\u00ed b\u00fdt regulov\u00e1ny jako\u00a0<\/span>selektovan\u00ed agens .\u201c<\/span><\/em><\/p>\n

To zachycuje n\u011bco, co se politick\u00fdm \u010dinitel\u016fm a ve\u0159ejnosti jen z\u0159\u00eddka \u0159\u00edk\u00e1 otev\u0159en\u011b.<\/span><\/p>\n

P\u0159\u00edstup ke genetick\u00e9mu pl\u00e1nu historick\u00e9ho pandemick\u00e9ho viru nen\u00ed ani hypotetick\u00fd, ani omezen\u00fd, ani p\u0159\u00edsn\u011b kontrolovan\u00fd.<\/span><\/p>\n

Nyn\u00ed je leg\u00e1ln\u011b dostupn\u00fd prost\u0159ednictv\u00edm b\u011b\u017en\u00fdch komer\u010dn\u00edch kan\u00e1l\u016f.<\/span><\/p>\n

Tato mezera v p\u0159\u00edstupu vyvol\u00e1v\u00e1 bezprost\u0159edn\u00ed obavy o n\u00e1rodn\u00ed bezpe\u010dnost a odhaluje regula\u010dn\u00ed syst\u00e9m, kter\u00fd tvrd\u00ed, \u017ee vykon\u00e1v\u00e1 p\u0159\u00edsnou kontrolu nad \u00fadajn\u011b pandemicky schopn\u00fdmi patogeny, a z\u00e1rove\u0148 umo\u017e\u0148uje cirkulaci jejich genetick\u00fdch slo\u017eek bez centr\u00e1ln\u00edho dohledu, meziresortn\u00ed kontroly a viditelnosti pro org\u00e1ny \u010dinn\u00e9 v trestn\u00edm \u0159\u00edzen\u00ed.<\/span><\/p>\n

\u201eKritick\u00e1 mezera v legislativ\u011b\u201c a \u201echybn\u00fd syst\u00e9m\u201c<\/span><\/h3>\n

Americk\u00e9 z\u00e1kony zakazuj\u00ed cel\u00e9 pandemick\u00e9 patogeny, nikoli v\u0161ak jejich slo\u017eky.<\/span><\/p>\n

To umo\u017e\u0148uje komukoli leg\u00e1ln\u011b koupit a sestavit DNA viru, kter\u00fd zabil 50 milion\u016f lid\u00ed, zat\u00edmco tlak trhu br\u00e1n\u00ed spole\u010dnostem kl\u00e1st ot\u00e1zky nebo to zastavit.<\/span><\/p>\n

\u201eSou\u010dasn\u00e9 americk\u00e9 p\u0159edpisy upravuj\u00edc\u00ed\u00a0<\/span>vybran\u00e9<\/span>\u00a0patogeny obsahuj\u00ed kritickou mezeru: zachycuj\u00ed intaktn\u00ed sekvence DNA schopn\u00e9 generovat \u0161kodliv\u00e9 patogeny, ale ignoruj\u00ed fragmenty DNA, kter\u00e9 m\u016f\u017ee sestavit kdokoli se skromn\u00fdmi laboratorn\u00edmi dovednostmi (obr. 1). V r\u00e1mci tohoto chybn\u00e9ho syst\u00e9mu nemaj\u00ed dodavatel\u00e9 \u017e\u00e1dnou z\u00e1konnou povinnost monitorovat ani omezovat p\u0159\u00edstup. Abychom tuto zranitelnost prozkoumali, fragmentovali jsme sekvence DNA k\u00f3duj\u00edc\u00ed ricinov\u00fd toxin nebo virus pandemick\u00e9 ch\u0159ipky z roku 1918 a objednali jsme 2\u20138 kus\u016f od ka\u017ed\u00e9ho od 38 dodavatel\u016f synt\u00e9zy DNA. Spole\u010dnosti spole\u010dn\u011b poskytly dostatek (leg\u00e1ln\u00edch) fragment\u016f o d\u00e9lce 400\u2013500 p\u00e1r\u016f b\u00e1z\u00ed k opakovan\u00e9mu generov\u00e1n\u00ed (neleg\u00e1ln\u00edch) intaktn\u00edch konstrukt\u016f. Laboratorn\u00ed testy ekvivalentn\u00edch ne\u0161kodn\u00fdch sekvenc\u00ed potvrdily, \u017ee tyto \u010d\u00e1sti lze sestavit do konstrukt\u016f, kter\u00e9 by mohl na z\u00e1klad\u011b ve\u0159ejn\u011b dostupn\u00fdch informac\u00ed vytvo\u0159it zku\u0161en\u00fd jedinec.\u201c Pomoc\u00ed dostupn\u00fdch protokol\u016f je nemo\u017en\u00e9 vytvo\u0159it virus, kter\u00fd kdysi zabil 50 milion\u016f lid\u00ed. Zodpov\u011bdn\u00e9 spole\u010dnosti \u010del\u00ed nemo\u017en\u00e9 volb\u011b: zav\u00e9st dobrovoln\u00e1 ochrann\u00e1 opat\u0159en\u00ed a potenci\u00e1ln\u011b ztratit obchody ve prosp\u011bch m\u00e9n\u011b opatrn\u00fdch konkurent\u016f \u2013 nebo dod\u00e1vat nebezpe\u010dn\u00e9, ale leg\u00e1ln\u00ed fragmenty. Tr\u017en\u00ed pob\u00eddky jim br\u00e1n\u00ed v ov\u011b\u0159en\u00ed na\u0161\u00ed identity, potvrzen\u00ed legitimn\u00edho v\u00fdzkumn\u00e9ho \u00fa\u010delu nebo koordinaci s ostatn\u00edmi, aby se zjistilo, zda se sna\u017e\u00edme z\u00edskat intaktn\u00ed patogen. Ot\u00e1zkou je, zda tv\u016frci politik aktualizuj\u00ed p\u0159edpisy\u00a0<\/span>t\u00fdkaj\u00edc\u00ed se vybran\u00fdch l\u00e1tek<\/span>\u00a0tak, aby zahrnovaly fragmenty DNA \u2013 vynucovan\u00e9 povinn\u00fdmi z\u00e1t\u011b\u017eov\u00fdmi testy, jako jsou ty pou\u017e\u00edvan\u00e9 v kybernetick\u00e9 bezpe\u010dnosti \u2013 aby se vyrovnaly podm\u00ednky a zabr\u00e1nilo se zneu\u017eit\u00ed.<\/span><\/em><\/p>\n

Objedn\u00e1vky bez registrace, ov\u011b\u0159en\u00ed nebo varovn\u00fdch zpr\u00e1v<\/span><\/h3>\n

Syst\u00e9m nezapomn\u011bl identifikovat pachatele zl\u00e9ho \u00famyslu.<\/span><\/p>\n

Ani se nezeptalo, zda herec existuje.<\/span><\/p>\n

Nebyla vy\u017eadov\u00e1na \u017e\u00e1dn\u00e1 kvalifikace, \u017e\u00e1dn\u00e1 instituce ani \u017e\u00e1dn\u00fd deklarovan\u00fd v\u00fdzkumn\u00fd \u00fa\u010del \u2013 proto\u017ee to z\u00e1kon nevy\u017eaduje.<\/span><\/p>\n

Dohled se nezhroutil; nikdy neza\u010dal.<\/span><\/p>\n

\u201eA\u010dkoli jsme pou\u017eili pseudonym bez jak\u00fdchkoli publikac\u00ed z oblasti molekul\u00e1rn\u00ed biologie a poskytli jsme adresu pro doru\u010dov\u00e1n\u00ed do kancel\u00e1\u0159e a kontaktn\u00ed informace \u010dist\u011b liter\u00e1rn\u011b orientovan\u00e9 neziskov\u00e9 organizace, kter\u00e1 v\u00fdslovn\u011b uvedla, \u017ee nem\u00e1 \u017e\u00e1dn\u00e9 laboratorn\u00ed z\u00e1zem\u00ed, obdr\u017eeli jsme fragmenty k\u00f3duj\u00edc\u00ed jak ricinov\u00fd toxin, tak virus ch\u0159ipky z roku 1918 od t\u00e9m\u011b\u0159 v\u0161ech dodavatel\u016f, ani\u017e bychom se zaregistrovali u Feder\u00e1ln\u00edho programu pro vybran\u00e9 agens (FSAP) nebo podali ozn\u00e1men\u00ed org\u00e1n\u016fm \u010dinn\u00fdm v trestn\u00edm \u0159\u00edzen\u00ed. Pro srovn\u00e1n\u00ed, v\u00fdzkumn\u00e1 za\u0159\u00edzen\u00ed, kter\u00e1 vlastn\u00ed\u00a0<\/span>vybran\u00e9 agens<\/span>\u00a0nebo intaktn\u00ed sekvence DNA dostate\u010dn\u00e9 k jejich generov\u00e1n\u00ed, se mus\u00ed zaregistrovat u FSAP, prok\u00e1zat odpov\u00eddaj\u00edc\u00ed vybaven\u00ed a bezpe\u010dnostn\u00ed protokoly, podstoupit prov\u011brku person\u00e1lu a udr\u017eovat p\u0159\u00edsn\u00e9 kontroly z\u00e1sob. Skute\u010dnost, \u017ee kdokoli m\u016f\u017ee leg\u00e1ln\u011b z\u00edskat DNA pot\u0159ebnou k vytvo\u0159en\u00ed stejn\u00fdch patogen\u016f objedn\u00e1n\u00edm fragment\u016f DNA, p\u0159edstavuje kritick\u00e9 selh\u00e1n\u00ed regula\u010dn\u00edho r\u00e1mce.\u201c<\/span><\/em><\/p>\n

Mont\u00e1\u017e potvrzena standardn\u00edmi laboratorn\u00edmi metodami<\/span><\/h3>\n

\u201eKomplement\u00e1rn\u00ed fragmenty by mohly b\u00fdt snadno sestaveny pomoc\u00ed metody Golden Gate, jedn\u00e9 z nejpou\u017e\u00edvan\u011bj\u0161\u00edch metod molekul\u00e1rn\u00edho klonov\u00e1n\u00ed.\u201c<\/span><\/em><\/p>\n

\u201eV\u0161ech 35 mutac\u00ed bylo s vysokou m\u00edrou \u00fasp\u011b\u0161nosti opraveno na prvn\u00ed pokus.\u201c<\/span><\/em><\/p>\n

To vylu\u010duje posledn\u00ed uklid\u0148uj\u00edc\u00ed p\u0159edpoklad \u2013 \u017ee i kdyby se DNA dala z\u00edskat, jej\u00ed sestaven\u00ed by bylo nep\u0159ekonateln\u011b obt\u00ed\u017en\u00e9.<\/span><\/p>\n

Popsan\u00e9 techniky jsou standardn\u00ed, publikovan\u00e9 a \u0161iroce vyu\u010dovan\u00e9.<\/span><\/p>\n

Rozd\u00edl mezi leg\u00e1ln\u00edm n\u00e1kupem a funk\u010dn\u00ed mont\u00e1\u017e\u00ed je mal\u00fd \u2013 a st\u00e1le se zmen\u0161uje.<\/span><\/p>\n

Dobrovoln\u00fd screening je \u201ez\u00e1sadn\u011b nedostate\u010dn\u00fd\u201c<\/span><\/h3>\n

\u201eZ 36 dodavatel\u016f, kte\u0159\u00ed zaslali fragmenty DNA leg\u00e1ln\u00edch\u00a0<\/span>select agent\u016f<\/span>\u00a0, pouze jeden vy\u017eadoval doklad o autorizaci t\u0159et\u00ed stranou.\u201c<\/span><\/em><\/p>\n

\u201ePoslali fragmenty, proto\u017ee byly leg\u00e1ln\u00ed a jednotliv\u011b ne\u0161kodn\u00e9.\u201c<\/span><\/em><\/p>\n

\u201eSou\u010dasn\u00e1 na\u0159\u00edzen\u00ed vytv\u00e1\u0159ej\u00ed trh, na kter\u00e9m jsou bezpe\u010dnostn\u00ed kompromisy efektivn\u011b odm\u011b\u0148ov\u00e1ny.\u201c<\/span><\/em><\/p>\n

To vysv\u011btluje, pro\u010d samoregulace v tomto odv\u011btv\u00ed nem\u016f\u017ee fungovat.<\/span><\/p>\n

Firmy, kter\u00e9 jsou pomalej\u0161\u00ed nebo kladou ot\u00e1zky, ztr\u00e1cej\u00ed zak\u00e1zky ve prosp\u011bch t\u011bch, kter\u00e9 to ned\u011blaj\u00ed.<\/span><\/p>\n

Pravidla up\u0159ednost\u0148uj\u00ed rychlost p\u0159ed pe\u010dlivost\u00ed, dodr\u017eov\u00e1n\u00ed p\u0159edpis\u016f p\u0159ed opatrnost\u00ed.<\/span><\/p>\n

To, co je ve\u0159ejn\u011b prezentov\u00e1no jako \u201ezodpov\u011bdn\u00e9 prom\u00edt\u00e1n\u00ed\u201c, se v praxi ukazuje jako voliteln\u00e9 divadlo.<\/span><\/p>\n

Z\u00e1t\u011b\u017eov\u00e9 testy po ozn\u00e1men\u00ed nad\u00e1le selh\u00e1valy<\/span><\/h3>\n

\u201eV\u0161ech osm vyslalo zcela neobalen\u00e9 fragmenty viru ch\u0159ipky z roku 1918.\u201c<\/span><\/em><\/p>\n

\u201eNikdo si ne\u017e\u00e1dal o povolen\u00ed, neov\u011b\u0159il na\u0161i toto\u017enost ani nenahl\u00e1sil podez\u0159el\u00fd pokus \u00fa\u0159ad\u016fm.\u201c<\/span><\/em><\/p>\n

Ani po odhalen\u00ed zranitelnosti \u2013 a to i pot\u00e9, co byly \u00fadajn\u011b informov\u00e1ny org\u00e1ny \u010dinn\u00e9 v trestn\u00edm \u0159\u00edzen\u00ed \u2013 se chov\u00e1n\u00ed nezm\u011bnilo.<\/span><\/p>\n

To podkop\u00e1v\u00e1 my\u0161lenku, \u017ee syst\u00e9m jednodu\u0161e pot\u0159ebuje v\u011bt\u0161\u00ed pov\u011bdom\u00ed nebo lep\u0161\u00ed komunikaci.<\/span><\/p>\n

Pob\u00eddky a opr\u00e1vn\u011bn\u00ed z\u016fst\u00e1vaj\u00ed nezm\u011bn\u011bny \u2013 proto z\u016fst\u00e1v\u00e1 nezm\u011bn\u011bn i v\u00fdsledek.<\/span><\/p>\n

Cena a kapacita<\/span><\/h3>\n

\u201eCelkov\u011b na\u0161e zji\u0161t\u011bn\u00ed ukazuj\u00ed, jak nedostate\u010dn\u00e9 regulace\u00a0<\/span>pro vybran\u00e9 agens<\/span>\u00a0br\u00e1n\u00ed i odpov\u011bdn\u00fdm poskytovatel\u016fm synt\u00e9zy DNA v d\u016fsledn\u00e9m zav\u00e1d\u011bn\u00ed \u017eivotn\u011b d\u016fle\u017eit\u00fdch ochrann\u00fdch opat\u0159en\u00ed. Syntetickou DNA dostate\u010dnou k vytvo\u0159en\u00ed infek\u010dn\u00edho viru ch\u0159ipky z roku 1918 po standardn\u00edm laboratorn\u00edm sestaven\u00ed lze zakoupit za p\u0159ibli\u017en\u011b 3 000 dolar\u016f; my jsme z\u00edskali dostatek fragment\u016f k zak\u00f3dov\u00e1n\u00ed viru n\u011bkolikr\u00e1t. D\u00edky tomu si kdokoli se skromn\u00fdmi laboratorn\u00edmi dovednostmi a p\u0159\u00edstupem ke standardn\u00edmu vybaven\u00ed m\u016f\u017ee objednat a sestavit fragmenty DNA dostate\u010dn\u00e9 k produkci vir\u016f a toxin\u016f\u00a0<\/span>vybran\u00fdch agens<\/span>\u00a0\u2013 v\u010detn\u011b pandemick\u00e9ho viru, kter\u00fd zabil p\u0159es 50 milion\u016f lid\u00ed.\u201c<\/span><\/em><\/p>\n

Tato schopnost je proto jednozna\u010dn\u011b v dosahu univerzit, za\u010d\u00ednaj\u00edc\u00edch podnik\u016f, soukrom\u00fdch laborato\u0159\u00ed a zahrani\u010dn\u00edch akt\u00e9r\u016f, kte\u0159\u00ed jednaj\u00ed pln\u011b v souladu se z\u00e1konem.<\/span><\/p>\n

Limituj\u00edc\u00edm faktorem nejsou pen\u00edze, infrastruktura ani p\u0159\u00edstup ke vz\u00e1cn\u00fdm materi\u00e1l\u016fm.<\/span><\/p>\n

Je to na\u0159\u00edzen\u00ed \u2013 a to moment\u00e1ln\u011b nefunguje.<\/span><\/p>\n

Selh\u00e1n\u00ed v posouzen\u00ed rizik<\/span><\/h3>\n

\u201eSkute\u010dnost, \u017ee bychom mohli leg\u00e1ln\u011b z\u00edskat fragmenty DNA prakticky od jak\u00e9hokoli poskytovatele genov\u00e9 synt\u00e9zy, kter\u00e9 by dohromady sta\u010dily k tomu, aby zku\u0161en\u00fd jedinec vytvo\u0159il virus, kter\u00fd kdysi zabil 50 milion\u016f lid\u00ed… p\u0159edstavuje pozoruhodn\u00e9 selh\u00e1n\u00ed v hodnocen\u00ed a zm\u00edr\u0148ov\u00e1n\u00ed spole\u010densk\u00fdch rizik.\u201c<\/span><\/em><\/p>\n

„Dobrovoln\u00e1 opat\u0159en\u00ed se uk\u00e1zala jako nedostate\u010dn\u00e1.“<\/span><\/em><\/p>\n

Tato pr\u00e1ce nepopisuje \u017e\u00e1dn\u00e1 budouc\u00ed rizika.<\/span><\/p>\n

Dokumentuje sou\u010dasn\u00fd stav.<\/span><\/p>\n

Vl\u00e1dy tvrd\u00ed, \u017ee p\u0159\u00edsn\u011b kontroluj\u00ed patogeny zp\u016fsobuj\u00edc\u00ed pandemie a z\u00e1rove\u0148 umo\u017e\u0148uj\u00ed voln\u00fd pohyb jejich kompletn\u00edch genetick\u00fdch slo\u017eek.<\/span><\/p>\n

Z\u00e1v\u011br<\/span><\/h3>\n

Nov\u00e1 studie\u00a0<\/span>agentury Nature Communications<\/span><\/em>\u00a0ukazuje, \u017ee kontroly biologick\u00e9 bezpe\u010dnosti v USA jsou do zna\u010dn\u00e9 m\u00edry symbolick\u00e9.<\/span><\/p>\n

Cel\u00e9 pandemick\u00e9 patogeny jsou regulov\u00e1ny, ale jejich DNA komponenty nikoli \u2013 co\u017e znamen\u00e1, \u017ee genetick\u00fd materi\u00e1l viru, kter\u00fd zabil 50 milion\u016f lid\u00ed, lze leg\u00e1ln\u011b koupit a sestavit podle sou\u010dasn\u00fdch z\u00e1kon\u016f.<\/span><\/p>\n

Jon Fleetwood<\/span><\/em><\/strong><\/p>\n<\/div>\n<\/div>\n

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Zdroj<\/span><\/a><\/span><\/h3>\n

 <\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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