{"id":92212,"date":"2025-11-14T04:28:43","date_gmt":"2025-11-14T03:28:43","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=92212"},"modified":"2025-11-14T04:28:43","modified_gmt":"2025-11-14T03:28:43","slug":"nova-studie-odhalila-ze-uzkostne-poruchy-souvisi-s-nizkou-hladinou-klicove-ziviny-cholinu-v-mozku","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2025\/11\/14\/nova-studie-odhalila-ze-uzkostne-poruchy-souvisi-s-nizkou-hladinou-klicove-ziviny-cholinu-v-mozku\/","title":{"rendered":"Nov\u00e1 studie odhalila, \u017ee \u00fazkostn\u00e9 poruchy souvis\u00ed s n\u00edzkou hladinou kl\u00ed\u010dov\u00e9 \u017eiviny cholinu v mozku"},"content":{"rendered":"
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Tich\u00e1 epidemie \u00fazkosti zm\u00edt\u00e1 sv\u011bt. Nejnov\u011bj\u0161\u00ed pr\u016flomov\u00fd nov\u00fd v\u00fdzkum v\u0161ak nazna\u010duje, \u017ee skryt\u00fd nutri\u010dn\u00ed nedostatek m\u016f\u017ee b\u00fdt kl\u00ed\u010dov\u00fdm chyb\u011bj\u00edc\u00edm kouskem skl\u00e1da\u010dky.<\/span><\/p>\n

V\u011bdci z\u00a0\u00a0<\/span>Kalifornsk\u00e9 univerzity UC Davis Health<\/span><\/em> zjistili, \u017ee lid\u00e9 trp\u00edc\u00ed \u00fazkostn\u00fdmi poruchami maj\u00ed v\u00fdrazn\u011b ni\u017e\u0161\u00ed hladiny \u017eivotn\u011b d\u016fle\u017eit\u00e9 mozkov\u00e9 \u017eiviny zvan\u00e9 cholin.<\/span><\/p>\n

Toto zji\u0161t\u011bn\u00ed, odhalen\u00e9 pomoc\u00ed neinvazivn\u00ed techniky zobrazov\u00e1n\u00ed mozku, nab\u00edz\u00ed nov\u00e9 biologick\u00e9 ch\u00e1p\u00e1n\u00ed \u00fazkosti a poukazuje na potenci\u00e1ln\u00ed nutri\u010dn\u00ed strategie pro miliony lid\u00ed hledaj\u00edc\u00edch \u00falevu.<\/span><\/p>\n

Studie publikovan\u00e1 v \u010dasopise\u00a0<\/span>Molecular Psychiatry<\/span><\/em>\u00a0p\u0159edstavuje prvn\u00ed metaanal\u00fdzu, kter\u00e1 identifikuje konzistentn\u00ed chemick\u00fd vzorec v mozku lid\u00ed s \u00fazkost\u00ed. V\u00fdzkumn\u00edci analyzovali \u00fadaje z 25 samostatn\u00fdch studi\u00ed a porovn\u00e1vali 370 lid\u00ed s \u00fazkostn\u00fdmi poruchami s 342 lidmi bez nich. V\u00fdsledky byly jasn\u00e9 a pozoruhodn\u00e9.<\/span><\/p>\n

Hladina cholinu byla v mozku lid\u00ed s \u00fazkost\u00ed p\u0159ibli\u017en\u011b o 8% ni\u017e\u0161\u00ed. Tento deficit byl nejv\u00fdrazn\u011bj\u0161\u00ed v prefront\u00e1ln\u00edm kortexu, oblasti mozku zodpov\u011bdn\u00e9 za kontrolu my\u0161len\u00ed, emoc\u00ed a chov\u00e1n\u00ed.<\/span><\/p>\n

\u201eToto je prvn\u00ed metaanal\u00fdza, kter\u00e1 ukazuje chemick\u00fd vzorec v mozku p\u0159i \u00fazkostn\u00fdch poruch\u00e1ch,\u201c<\/span><\/em>\u00a0\u0159ekl Jason Smucny, spoluautor studie a odborn\u00fd asistent na Kated\u0159e psychiatrie a behavior\u00e1ln\u00edch v\u011bd.<\/span><\/p>\n

\u201eTento objev nazna\u010duje, \u017ee nutri\u010dn\u00ed p\u0159\u00edstupy \u2013 jako nap\u0159\u00edklad vhodn\u00e1 suplementace cholinu \u2013 mohou pomoci obnovit chemii mozku a zlep\u0161it v\u00fdsledky l\u00e9\u010dby pacient\u016f.\u201c<\/span><\/em><\/p>\n

Rozs\u00e1hl\u00e1 krize du\u0161evn\u00edho zdrav\u00ed<\/span><\/h2>\n

D\u016fsledky tohoto v\u00fdzkumu jsou vzhledem k samotn\u00e9mu rozsahu probl\u00e9mu rozs\u00e1hl\u00e9. Richard Maddock, hlavn\u00ed autor studie a psychiatr, zd\u016fraznil v\u0161udyp\u0159\u00edtomnou povahu t\u011bchto psychick\u00fdch stav\u016f.<\/span><\/p>\n

\u201e\u00dazkostn\u00e9 poruchy jsou nej\u010dast\u011bj\u0161\u00ed du\u0161evn\u00ed chorobou a postihuj\u00ed p\u0159ibli\u017en\u011b 30% dosp\u011bl\u00fdch,\u201c<\/span><\/em>\u00a0\u0159ekl Maddock.\u00a0<\/span>\u201eMohou b\u00fdt pro lidi skli\u010duj\u00edc\u00ed, p\u0159i\u010dem\u017e mnoz\u00ed nedost\u00e1vaj\u00ed p\u0159im\u011b\u0159enou l\u00e9\u010dbu.\u201c<\/span><\/em><\/p>\n

Mezi tyto poruchy pat\u0159\u00ed v\u0161eobecn\u00e1 \u00fazkost, panick\u00e1 porucha, soci\u00e1ln\u00ed \u00fazkost a fobie.<\/span><\/p>\n

V\u00fdzkumn\u00fd t\u00fdm teoretizuje, \u017ee neust\u00e1l\u00fd stav vysok\u00e9 bd\u011blosti nebo aktivity v r\u00e1mci prav\u011bk\u00e9ho reflexu \u201ebojuj nebo ute\u010d\u201c, kter\u00fd za\u017e\u00edvaj\u00ed lid\u00e9 s \u00fazkost\u00ed, z\u0159ejm\u011b zvy\u0161uje popt\u00e1vku mozku po chol\u00edn\u011b, \u010d\u00edm\u017e se sni\u017euje jeho hladina.<\/span><\/p>\n

Zat\u00edmco 8% sn\u00ed\u017een\u00ed se m\u016f\u017ee zd\u00e1t mal\u00e9, v citliv\u00e9m prost\u0159ed\u00ed mozku je velmi v\u00fdznamn\u00e9.<\/span><\/p>\n

\u201eO 8% ni\u017e\u0161\u00ed mno\u017estv\u00ed nezn\u00ed a\u017e tak mnoho, ale v mozku je to v\u00fdznamn\u00e9<\/span><\/em> ,\u201c potvrdil Maddock.<\/span><\/p>\n

Kl\u00ed\u010dov\u00fd \u00fakol chol\u00ednu<\/span><\/h2>\n

Cholin je esenci\u00e1ln\u00ed \u017eivina, co\u017e znamen\u00e1, \u017ee si jej t\u011blo nedok\u00e1\u017ee samo vyrobit v dostate\u010dn\u00e9m mno\u017estv\u00ed, proto se mus\u00ed p\u0159ij\u00edmat prost\u0159ednictv\u00edm stravy. P\u0159edstavuje z\u00e1kladn\u00ed stavebn\u00ed k\u00e1men bun\u011b\u010dn\u00fdch membr\u00e1n a je nezbytn\u00fd pro mozkov\u00e9 funkce, v\u010detn\u011b pam\u011bti, regulace n\u00e1lady a kontroly sval\u016f.<\/span><\/p>\n

Cholin slou\u017e\u00ed jako prekurzor acetylcholinu, \u017eivotn\u011b d\u016fle\u017eit\u00e9ho neurotransmiteru nezbytn\u00e9ho pro funkci mozku. N\u011bkter\u00e9 l\u00e9ky na demenci jsou nap\u0159\u00edklad zam\u011b\u0159eny na zv\u00fd\u0161en\u00ed hladiny acetylcholinu.<\/span><\/p>\n

Tento nov\u00fd v\u00fdzkum je v souladu s rostouc\u00edm mno\u017estv\u00edm d\u016fkaz\u016f, kter\u00e9 poukazuj\u00ed na masov\u00fd nedostatek cholinu mezi obyvatelstvem. Nez\u00e1visl\u00e9 anal\u00fdzy nazna\u010dily, \u017ee p\u0159ibli\u017en\u011b 90% lid\u00ed nekonzumuje doporu\u010den\u00e9 denn\u00ed mno\u017estv\u00ed cholinu.<\/span><\/p>\n

Tento roz\u0161\u00ed\u0159en\u00fd nedostatek pak vytv\u00e1\u0159\u00ed podm\u00ednky pro krizi ve\u0159ejn\u00e9ho zdrav\u00ed a m\u016f\u017ee p\u0159isp\u011bt nejen k \u00fazkosti, ale tak\u00e9 k dal\u0161\u00edm probl\u00e9m\u016fm, jako jsou\u00a0<\/span>\u00fanava<\/span><\/a>\u00a0, probl\u00e9my s pam\u011bt\u00ed a ztukovat\u011bn\u00ed jater.<\/span><\/p>\n

V\u00fdzkumn\u00edci jsou opatrn\u011b optimisti\u010dt\u00ed a maj\u00ed jasno v dal\u0161\u00edch kroc\u00edch:<\/span><\/p>\n

„Zat\u00edm nev\u00edme, zda zv\u00fd\u0161en\u00ed cholinu ve strav\u011b pom\u016f\u017ee sn\u00ed\u017eit \u00fazkost. Bude zapot\u0159eb\u00ed dal\u0161\u00ed v\u00fdzkum,“<\/span><\/em>\u00a0uvedl Maddock a varoval p\u0159ed samol\u00e9\u010dbou vysok\u00fdmi d\u00e1vkami dopl\u0148k\u016f, ale z\u00e1rove\u0148 zd\u016fraznil z\u00e1sadn\u00ed v\u00fdznam stravy bohat\u00e9 na \u017eiviny pro du\u0161evn\u00ed zdrav\u00ed.<\/span><\/p>\n

Kde z\u00edskat cholin<\/span><\/h2>\n

Kde tedy lze nal\u00e9zt tuto kl\u00ed\u010dovou \u017eivinu? Odpov\u011bd\u00ed jsou zdrav\u00e9, p\u0159\u00edrodn\u00ed potraviny.<\/span><\/p>\n

\u201eN\u011bkdo s \u00fazkostnou poruchou by se m\u011bl pod\u00edvat na svou stravu a zjistit, zda p\u0159ij\u00edm\u00e1 doporu\u010den\u00e9 denn\u00ed mno\u017estv\u00ed cholinu,\u201c<\/span><\/em>\u00a0poradil Maddock.<\/span><\/p>\n

Konkr\u00e9tn\u011b poznamenal, \u017ee n\u011bkter\u00e9 formy omega-3 mastn\u00fdch kyselin, jako nap\u0159\u00edklad ty, kter\u00e9 se nach\u00e1zej\u00ed v\u00a0<\/span>lososech<\/span><\/strong>\u00a0, mohou b\u00fdt obzvl\u00e1\u0161t\u011b dobr\u00fdm zdrojem pro dod\u00e1v\u00e1n\u00ed cholinu do mozku.<\/span><\/p>\n

Mezi dal\u0161\u00ed vynikaj\u00edc\u00ed zdroje pat\u0159\u00ed:<\/span><\/strong><\/p>\n