{"id":89652,"date":"2025-10-11T04:08:22","date_gmt":"2025-10-11T02:08:22","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=89652"},"modified":"2025-10-11T04:08:22","modified_gmt":"2025-10-11T02:08:22","slug":"tichy-pozar-prulomova-lekarska-zprava-prohlasila-zanet-hlavniho-vinika-srdecnich-onemocneni","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2025\/10\/11\/tichy-pozar-prulomova-lekarska-zprava-prohlasila-zanet-hlavniho-vinika-srdecnich-onemocneni\/","title":{"rendered":"Tich\u00fd po\u017e\u00e1r: Pr\u016flomov\u00e1 l\u00e9ka\u0159sk\u00e1 zpr\u00e1va prohl\u00e1sila z\u00e1n\u011bt hlavn\u00edho vin\u00edka srde\u010dn\u00edch onemocn\u011bn\u00ed"},"content":{"rendered":"
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Americk\u00e1 kardiologick\u00e1 akademie (ACC) ofici\u00e1ln\u011b uznala chronick\u00fd z\u00e1n\u011bt za siln\u00fd a nez\u00e1visl\u00fd faktor p\u0159edpov\u00eddaj\u00edc\u00ed srde\u010dn\u00ed onemocn\u011bn\u00ed.<\/span><\/strong><\/p>\n

Ned\u00e1vn\u00e9 v\u011bdeck\u00e9 prohl\u00e1\u0161en\u00ed skupiny, publikovan\u00e9 29. z\u00e1\u0159\u00ed 2025 v odborn\u00e9m \u010dasopise\u00a0<\/span>Journal of the American College of Cardiology<\/span><\/em> , vyz\u00fdv\u00e1 k m\u011b\u0159en\u00ed z\u00e1n\u011btu spolu s cholesterolem pro posouzen\u00ed rizika infarktu a mozkov\u00e9 p\u0159\u00edhody.<\/span><\/p>\n

Toto doporu\u010den\u00ed signalizuje z\u00e1sadn\u00ed zm\u011bnu ve zp\u016fsobu hodnocen\u00ed kardiovaskul\u00e1rn\u00edho zdrav\u00ed, kter\u00e1 se posouv\u00e1 od \u00fazk\u00e9ho zam\u011b\u0159en\u00ed na lipidy (cholesterolu) k boji proti doutnaj\u00edc\u00edmu vnit\u0159n\u00edmu ohni, kter\u00fd \u010dasto re\u00e1ln\u011b zapaluje srde\u010dn\u00ed krizi.<\/span><\/p>\n

Po cel\u00e9 generace se boj ve\u0159ejn\u00e9ho zdravotnictv\u00ed proti srde\u010dn\u00edm chorob\u00e1m odehr\u00e1v\u00e1 p\u0159edev\u0161\u00edm na front\u011b vysok\u00e9ho krevn\u00edho tlaku a cholesterolu.<\/span><\/p>\n

Pacienti znaj\u00ed pojmy jako \u201edobr\u00fd\u201c \u010di \u201e\u0161patn\u00fd\u201c cholesterol. L\u00e9ky\u00a0<\/span>statiny<\/span><\/a>\u00a0ke sn\u00ed\u017een\u00ed \u201e\u0161patn\u00e9ho\u201c LDL cholesterolu (lipoprotein\u016f s n\u00edzkou hustotou) se staly jedn\u011bmi z nej\u010dast\u011bji p\u0159edepisovan\u00fdch l\u00e9k\u016f na sv\u011bt\u011b.<\/span><\/p>\n

Tento p\u0159\u00edstup v\u0161ak zanechal nezodpov\u011bzenou kritickou ot\u00e1zku: Pro\u010d tolik lid\u00ed se zd\u00e1nliv\u011b p\u0159ijateln\u00fdmi hladinami cholesterolu st\u00e1le trp\u00ed ni\u010div\u00fdmi kardiovaskul\u00e1rn\u00edmi p\u0159\u00edhodami?<\/span><\/p>\n

Nov\u00e9 pokyny ACC poskytuje jasnou odpov\u011b\u010f a poukazuje na chronick\u00fd z\u00e1n\u011bt jako chyb\u011bj\u00edc\u00ed d\u00edlek diagnostick\u00e9 skl\u00e1da\u010dky.<\/span><\/p>\n

Z\u00e1kladem tohoto nov\u00e9ho p\u0159\u00edstupu je specifick\u00fd krevn\u00ed test, kter\u00fd je dostupn\u00fd ji\u017e l\u00e9ta, ale teprve nyn\u00ed byl pov\u00fd\u0161en na prim\u00e1rn\u00ed screeningov\u00fd n\u00e1stroj. Jedn\u00e1 se o vysoce citliv\u00fd\u00a0<\/span>test C-reaktivn\u00edho proteinu (hsCRP)<\/span><\/strong>\u00a0.<\/span><\/p>\n

C-reaktivn\u00ed protein je l\u00e1tka produkovan\u00e1 j\u00e1try v reakci na z\u00e1n\u011bt kdekoli v t\u011ble. Vysoce citliv\u00fd test dok\u00e1\u017ee zjistit i n\u00edzk\u00e9 hladiny tohoto proteinu, \u010d\u00edm\u017e odhal\u00ed stav p\u0159etrv\u00e1vaj\u00edc\u00edho z\u00e1n\u011btu n\u00edzk\u00e9ho stupn\u011b, kter\u00fd dr\u00e1\u017ed\u00ed c\u00e9vy a podporuje rozvoj arteri\u00e1ln\u00edho onemocn\u011bn\u00ed.<\/span><\/p>\n

Nov\u00fd klinick\u00fd standard<\/span><\/h2>\n

Ve zpr\u00e1v\u011b se uv\u00e1d\u00ed, \u017ee jeliko\u017e l\u00e9ka\u0159i nel\u00e9\u010d\u00ed to, co nenam\u011b\u0159\u00ed, univerz\u00e1ln\u00ed screening hsCRP se dnes doporu\u010duje u pacient\u016f se zn\u00e1m\u00fdm srde\u010dn\u00edm onemocn\u011bn\u00edm, ale i bez n\u011bj.<\/span><\/p>\n

Zpr\u00e1va d\u00e1le \u0159\u00edk\u00e1, \u017ee u pacient\u016f s diagnostikovan\u00fdm kardiovaskul\u00e1rn\u00edm onemocn\u011bn\u00edm je vysok\u00e1 hladina hsCRP p\u0159inejmen\u0161\u00edm stejn\u011b prediktivn\u00ed pro budouc\u00ed infarkt nebo mozkovou p\u0159\u00edhodu jako vysok\u00e1 hladina LDL cholesterolu.<\/span><\/p>\n

To plat\u00ed i pro pacienty, kte\u0159\u00ed ji\u017e u\u017e\u00edvaj\u00ed statiny, co\u017e nazna\u010duje, \u017ee kontrola cholesterolu sama o sob\u011b ne v\u017edy eliminuje riziko z\u00e1n\u011btu.<\/span><\/p>\n

Toto p\u0159edstavuje monument\u00e1ln\u00ed posun v klinick\u00e9 strategii. Z\u00e1n\u011bt se tak posouv\u00e1 ze sekund\u00e1rn\u00edho probl\u00e9mu na centr\u00e1ln\u00ed biomarker, kter\u00fd je na stejn\u00e9 \u00farovni jako tradi\u010dn\u00ed ukzovat cholesterolu.<\/span><\/p>\n

D\u016fsledky jsou rozs\u00e1hl\u00e9 a nazna\u010duj\u00ed, \u017ee miliony pacient\u016f, kte\u0159\u00ed jsou v sou\u010dasnosti pova\u017eov\u00e1ni za \u201ezvl\u00e1dnut\u00e9\u201c na statinov\u00e9 l\u00e9\u010db\u011b, mohou st\u00e1le n\u00e9st v\u00fdznamn\u00e9 rezidu\u00e1ln\u00ed riziko, pokud jejich z\u00e1n\u011bt z\u016fstane mimo kontrolu.<\/span><\/p>\n

Zpr\u00e1va trv\u00e1 na tom, \u017ee p\u0159etrv\u00e1vaj\u00edc\u00ed vysok\u00e9 hodnoty hsCRP by m\u011bly v\u00e9st l\u00e9ka\u0159e ke zv\u00e1\u017een\u00ed zah\u00e1jen\u00ed nebo zintenzivn\u011bn\u00ed l\u00e9\u010dby z\u00e1n\u011bt\u016f bez ohledu na to, co ukazuje hodnota LDL cholesterolu pacienta.<\/span><\/p>\n

\u017divotn\u00ed styl jako l\u00e9k<\/span><\/h2>\n

Asi nejpovzbuzuj\u00edc\u00ed \u010d\u00e1st\u00ed nov\u00fdch doporu\u010den\u00ed je jejich siln\u00fd d\u016fraz na \u017eivotn\u00ed styl jako prim\u00e1rn\u00ed protiz\u00e1n\u011btlivou strategii. ACC poskytuje jasn\u00e9 a praktick\u00e9 pokyny pro jednotlivce, u kter\u00fdch se zjistily vysok\u00e9 z\u00e1n\u011btliv\u00e9 markery.<\/span><\/p>\n

Doporu\u010den\u00e1 strava odr\u00e1\u017e\u00ed\u00a0<\/span>st\u0159edomo\u0159sk\u00fd vzorec<\/span><\/strong>\u00a0, p\u0159i\u010dem\u017e klade d\u016fraz na konzumaci:<\/span><\/p>\n