{"id":88637,"date":"2025-09-26T07:17:50","date_gmt":"2025-09-26T05:17:50","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=88637"},"modified":"2025-09-26T07:17:50","modified_gmt":"2025-09-26T05:17:50","slug":"vedecky-prulom-kmenove-bunky-opravuji-poskozeni-po-mrtvici","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2025\/09\/26\/vedecky-prulom-kmenove-bunky-opravuji-poskozeni-po-mrtvici\/","title":{"rendered":"V\u011bdeck\u00fd pr\u016flom: Kmenov\u00e9 bu\u0148ky opravuj\u00ed po\u0161kozen\u00ed po mrtvici"},"content":{"rendered":"
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Mohla by jednoduch\u00e1 terapie kmenov\u00fdmi bu\u0148kami zvr\u00e1tit \u00fa\u010dinky mrtvice? Nov\u011b publikovan\u00e1 studie nab\u00edz\u00ed nad\u011bji. Pro farmaceutick\u00e9 firmy je to v\u0161ak \u0161patn\u00e1 zpr\u00e1va, zejm\u00e9na proto, \u017ee tyto spole\u010dnosti tak\u00e9 vyd\u011bl\u00e1vaj\u00ed na pacientech s mrtvic\u00ed spoustu pen\u011bz.<\/span><\/strong><\/p>\n

Po cel\u00e1 desetilet\u00ed se modern\u00ed konven\u010dn\u00ed medic\u00edna spol\u00e9hala na zvl\u00e1d\u00e1n\u00ed symptom\u016f. Pilulky sem, tablety tam a \u0159ada rehabilita\u010dn\u00edch opat\u0159en\u00ed, kter\u00e1 nakonec jen z\u0159\u00eddka spln\u00ed to, co pacient\u016fm slibuj\u00ed. Zejm\u00e9na pokud jde o mrtvici \u2013 jednu z nejroz\u0161\u00ed\u0159en\u011bj\u0161\u00edch nemoc\u00ed na\u0161\u00ed doby \u2013 plat\u00ed star\u00e9 p\u0159\u00edslov\u00ed: jednou je to zlomen\u00e9, zlomen\u00e9 to z\u016fstane. Paral\u00fdza, poruchy \u0159e\u010di a kognitivn\u00ed po\u0161kozen\u00ed. Miliony pacient\u016f musely sn\u00e1\u0161et sv\u016fj osud. V\u011bdci z Univerzity v Curychu v\u0161ak nyn\u00ed dos\u00e1hli n\u011b\u010deho, co by mohlo zm\u011bnit pravidla hry: doslova regenerovali zni\u010denou mozkovou tk\u00e1\u0148 pomoc\u00ed kmenov\u00fdch bun\u011bk. Studie byla publikov\u00e1na v \u010dasopise Nature Communications pod n\u00e1zvem \u201e\u00a0<\/span>Neur\u00e1ln\u00ed xenografty p\u0159isp\u00edvaj\u00ed k dlouhodob\u00e9mu zotaven\u00ed po mrtvici prost\u0159ednictv\u00edm molekul\u00e1rn\u00edho p\u0159eslechu \u0161t\u011bpu a hostitele<\/span><\/a> .\u201c<\/span><\/p>\n

V experimentech na zv\u00ed\u0159atech byly lidsk\u00e9 nervov\u00e9 kmenov\u00e9 bu\u0148ky odvozen\u00e9 z indukovan\u00fdch pluripotentn\u00edch kmenov\u00fdch bun\u011bk transplantov\u00e1ny do mozk\u016f my\u0161\u00ed. A hle, b\u011bhem n\u011bkolika t\u00fddn\u016f se tyto bu\u0148ky vyvinuly ve funk\u010dn\u00ed neurony, kter\u00e9 se integrovaly do st\u00e1vaj\u00edc\u00edch s\u00edt\u00ed. Nejen to, ale tak\u00e9 se regenerovaly krevn\u00ed c\u00e9vy, zm\u00edrnil se z\u00e1n\u011bt a pos\u00edlila se hematoencefalick\u00e1 bari\u00e9ra. My\u0161i, kter\u00e9 d\u0159\u00edve t\u011b\u017ece prod\u011blaly mrtvici, se mohly op\u011bt norm\u00e1ln\u011b pohybovat, jak prok\u00e1zala anal\u00fdza ch\u016fze s pomoc\u00ed um\u011bl\u00e9 inteligence.<\/span><\/p>\n

A to nen\u00ed v\u0161e: Kl\u00ed\u010dov\u00fdm zji\u0161t\u011bn\u00edm je, \u017ee l\u00e9\u010dba byla obzvl\u00e1\u0161t\u011b \u00fa\u010dinn\u00e1, pokud byla pod\u00e1na p\u0159ibli\u017en\u011b t\u00fdden po mrtvici. To je p\u0159esn\u011b \u010dasov\u00fd r\u00e1mec, kter\u00fd by byl skute\u010dn\u011b pou\u017eiteln\u00fd v re\u00e1ln\u00e9m klinick\u00e9m prost\u0159ed\u00ed. A zat\u00edmco v\u011bdci st\u00e1le pracuj\u00ed na v\u00fdvoji metody od invazivn\u00edch injekc\u00ed do mozku k m\u00e9n\u011b rizikov\u00fdm postup\u016fm, jako je endovaskul\u00e1rn\u00ed pod\u00e1n\u00ed, skute\u010dn\u00fd probl\u00e9m nespo\u010d\u00edv\u00e1 v biologii, ale v politice a ekonomick\u00fdch struktur\u00e1ch.<\/span><\/p>\n

Koneckonc\u016f, co to znamen\u00e1 pro farmaceutick\u00fd pr\u016fmysl s obratem v \u0159\u00e1du miliard dolar\u016f, kter\u00fd po cel\u00e1 desetilet\u00ed \u0161t\u011bd\u0159e profituje z toho, \u017ee pacienty po mrtvici dr\u017e\u00ed v celo\u017eivotn\u00edch rehabilita\u010dn\u00edch smy\u010dk\u00e1ch s koktejly l\u00e9k\u016f? L\u00e9\u010debn\u00fd p\u0159\u00edstup, kter\u00fd skute\u010dn\u011b regeneruje, by tento cyklus prolomil. Je to stejn\u00fd z\u00e1kladn\u00ed konflikt, jak\u00fd vid\u00edme u jin\u00fdch nemoc\u00ed: Terapie, kter\u00e9 skute\u010dn\u011b slibuj\u00ed vyl\u00e9\u010den\u00ed, jsou \u010dasto za\u0161katulkov\u00e1ny, odlo\u017eeny nebo torp\u00e9dov\u00e1ny nekone\u010dn\u00fdmi bezpe\u010dnostn\u00edmi obavami, zat\u00edmco nov\u00e9 \u00fasp\u011b\u0161n\u00e9 l\u00e9ky jsou schvalov\u00e1ny zrychlen\u00fdmi postupy.<\/span><\/p>\n

Cury\u0161sk\u00e1 studie jasn\u011b ukazuje, \u017ee regenerativn\u00ed medic\u00edna u\u017e nen\u00ed vzd\u00e1len\u00fdm snem.\u00a0<\/span>Klinick\u00e9 studie s podobn\u00fdmi postupy kmenov\u00fdch bun\u011bk pro l\u00e9\u010dbu Parkinsonovy choroby<\/span><\/a>\u00a0ji\u017e v Japonsku prob\u00edhaj\u00ed . Pokud by se stejn\u00fd p\u0159\u00edstup nyn\u00ed zp\u0159\u00edstupnil pacient\u016fm po mrtvici, hovo\u0159ili bychom o revoluci v neurologii. Pacient, kter\u00fd se uzdrav\u00ed, v\u0161ak ji\u017e nen\u00ed plat\u00edc\u00edm z\u00e1kazn\u00edkem. Jak tedy zareaguj\u00ed velk\u00e9 farmaceutick\u00e9 spole\u010dnosti?<\/span><\/p>\n

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Mohla by jednoduch\u00e1 terapie kmenov\u00fdmi bu\u0148kami zvr\u00e1tit \u00fa\u010dinky mrtvice? Nov\u011b publikovan\u00e1 studie nab\u00edz\u00ed nad\u011bji. Pro…<\/p>\n","protected":false},"author":2,"featured_media":88638,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[9814,1807,1561,21],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/88637"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=88637"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/88637\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/88638"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=88637"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=88637"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=88637"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}