{"id":88499,"date":"2025-09-25T00:23:24","date_gmt":"2025-09-24T22:23:24","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=88499"},"modified":"2025-09-24T11:20:40","modified_gmt":"2025-09-24T09:20:40","slug":"nova-studie-odhalila-sokujici-rizika-beta-blokatoru-leku-masove-predepisovanych-po-prekonani-infarktu","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2025\/09\/25\/nova-studie-odhalila-sokujici-rizika-beta-blokatoru-leku-masove-predepisovanych-po-prekonani-infarktu\/","title":{"rendered":"Nov\u00e1 studie odhalila \u0161okuj\u00edc\u00ed rizika beta-blok\u00e1tor\u016f \u2013 l\u00e9k\u016f masov\u011b p\u0159edepisovan\u00fdch po p\u0159ekon\u00e1n\u00ed infarktu"},"content":{"rendered":"
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Beta-blok\u00e1tory byly po desetilet\u00ed z\u00e1kladn\u00edm kamenem l\u00e9\u010dby infarktu, ka\u017edoro\u010dn\u011b se p\u0159edepisovaly des\u00edtk\u00e1m milion\u016fm pacient\u016f v USA a Evrop\u011b jako zp\u016fsob sn\u00ed\u017een\u00ed krevn\u00edho tlaku, prevence druh\u00e9ho infarktu a dokonce i mimo schv\u00e1len\u00e9 indikace na zm\u00edr\u0148ov\u00e1n\u00ed \u00fazkosti.<\/span><\/p>\n

Nar\u016fstaj\u00edc\u00ed d\u016fkazy v\u0161ak nazna\u010duj\u00ed, \u017ee tyto l\u00e9ky, kter\u00e9 jsou dodnes slaveny jako zachr\u00e1nci \u017eivota, nemus\u00ed b\u00fdt pro v\u011bt\u0161inu pacient\u016f pot\u0159ebn\u00e9 a pro \u017eeny jsou vysloven\u011b nebezpe\u010dn\u00e9.<\/span><\/p>\n

Pr\u016flomov\u00e1 studie publikovan\u00e1 v\u00a0<\/span>European Heart Journal (Evropsk\u00fd \u017eurn\u00e1l srdce<\/span><\/em>\u00a0) zjistila, \u017ee \u017eeny s norm\u00e1ln\u00ed funkc\u00ed srdce po infarktu, kter\u00e9 u\u017e\u00edvaly beta-blok\u00e1tory, m\u011bly o 45% vy\u0161\u0161\u00ed pravd\u011bpodobnost \u00famrt\u00ed, dal\u0161\u00edho infarktu nebo hospitalizace pro srde\u010dn\u00ed selh\u00e1n\u00ed.<\/span><\/p>\n

Je\u0161t\u011b alarmuj\u00edc\u00ed je, \u017ee vysok\u00e9 d\u00e1vky beta-blok\u00e1tor\u016f zv\u00fd\u0161ily riziko \u00famrt\u00ed \u017een t\u00e9m\u011b\u0159 trojn\u00e1sobn\u011b. Mu\u017ei ve stejn\u00e9 studii neprok\u00e1zali takov\u00e9 po\u0161kozen\u00ed, co\u017e vyvol\u00e1v\u00e1 v\u00e1\u017en\u00e9 ot\u00e1zky o tom, pro\u010d tyto l\u00e9ky z\u016fst\u00e1vaj\u00ed univerz\u00e1ln\u011b p\u0159edepisovan\u00fdm l\u00e9\u010divem.<\/span><\/p>\n

40let\u00e1 l\u00e9ka\u0159sk\u00e1 rutina pod palbou kritiky<\/span><\/h2>\n

Studie REBOOT, nejv\u011bt\u0161\u00ed sv\u00e9ho druhu, sledovala t\u00e9m\u011b\u0159 4 roky v\u00edce ne\u017e 8 500 pacient\u016f, kte\u0159\u00ed p\u0159e\u017eili infarkt ve \u0160pan\u011blsku a It\u00e1lii.<\/span><\/p>\n

V\u00fdsledky byly jasn\u00e9: beta-blok\u00e1tory nep\u0159inesly \u017e\u00e1dn\u00fd u\u017eitek pacient\u016fm se zachovanou funkc\u00ed srdce, tedy skupin\u011b, kter\u00e1 dnes tvo\u0159\u00ed v\u011bt\u0161inu p\u0159\u00edpad\u016f infarktu. P\u0159esto je v\u00edce ne\u017e 80 procent t\u011bchto pacient\u016f st\u00e1le pos\u00edl\u00e1no dom\u016f s p\u0159edpisem na betablok\u00e1tory, \u010dasto na do\u017eivot\u00ed.<\/span><\/p>\n

Dr. Borja Ib\u00e1\u00f1ez, vedouc\u00ed v\u00fdzkumn\u00edk studie, ozna\u010dil zji\u0161t\u011bn\u00ed za \u201ejeden z nejv\u00fdznamn\u011bj\u0161\u00edch pokrok\u016f v l\u00e9\u010db\u011b infarktu za posledn\u00ed desetilet\u00ed\u201c.<\/span><\/p>\n

Star\u00e9 zvyky se v\u0161ak t\u011b\u017eko p\u0159ekon\u00e1vaj\u00ed. Mnoz\u00ed l\u00e9ka\u0159i tak nad\u00e1le p\u0159edepisuj\u00ed beta-blok\u00e1tory na z\u00e1klad\u011b tradice, nikoli na z\u00e1klad\u011b nejnov\u011bj\u0161\u00edch v\u011bdeck\u00fdch d\u016fkaz\u016f.<\/span><\/p>\n

Od l\u00e9k\u016f na srdce po m\u00f3dn\u00ed l\u00e9k hollywoodsk\u00fdch celebrit proti \u00fazkosti<\/span><\/h2>\n

Beta-blok\u00e1tory jako propranolol (na Slovensku obchodn\u00ed n\u00e1zev l\u00e9ku je Hemangiol) se staly trendov\u00fdm rychl\u00fdm \u0159e\u0161en\u00edm \u00fazkosti, nervozity na prvn\u00edm rande a dokonce i tr\u00e9my z ve\u0159ejn\u00e9ho vystupov\u00e1n\u00ed.<\/span><\/p>\n

Celebrity od Roberta Downeyho juniora po Kristen Bellovou otev\u0159en\u011b chv\u00e1l\u00ed tyto l\u00e9ky na uklidn\u011bn\u00ed nerv\u016f. Odborn\u00edci v\u0161ak varuj\u00ed, \u017ee jejich pou\u017eit\u00ed mimo schv\u00e1len\u00e9 indikace nen\u00ed ov\u011b\u0159eno a potenci\u00e1ln\u011b riskantn\u00ed.<\/span><\/p>\n

Dr. Jack Wolfson, kardiolog a zakladatel spole\u010dnosti\u00a0<\/span>Natural Heart Doctor<\/span><\/em> (P\u0159\u00edrodn\u00ed kardiolog), pro port\u00e1l The Epoch Times \u0159ekl:<\/span><\/p>\n

\u201eVe\u0159ejn\u00ed \u0159e\u010dn\u00edci nemaj\u00ed \u201enedostatek\u201c beta-blok\u00e1tor\u016f. Jejich u\u017e\u00edv\u00e1n\u00ed na \u00fazkost nebo pro dosa\u017een\u00ed lep\u0161\u00edho ment\u00e1ln\u00edho v\u00fdkonu ignoruje z\u00e1kladn\u00ed p\u0159\u00ed\u010dinu jejich probl\u00e9mu.\u201c<\/span><\/em><\/p>\n

Mezit\u00edm se vedlej\u0161\u00ed \u00fa\u010dinky jako \u00fanava, p\u0159ib\u00fdv\u00e1n\u00ed na v\u00e1ze, erektiln\u00ed dysfunkce \u010di dokonce zv\u00fd\u0161en\u00e9 riziko cukrovky s pacienty diskutuj\u00ed jen z\u0159\u00eddka.<\/span><\/p>\n

Syst\u00e9m hl\u00e1\u0161en\u00ed ne\u017e\u00e1douc\u00edch ud\u00e1lost\u00ed americk\u00e9ho regula\u010dn\u00edho \u00fa\u0159adu FDA zaznamenal t\u00e9m\u011b\u0159 63 000 z\u00e1va\u017en\u00fdch p\u0159\u00edpad\u016f souvisej\u00edc\u00edch pouze s beta-blok\u00e1torem Metoprololem, v\u010detn\u011b v\u00edce ne\u017e 9 400 \u00famrt\u00ed.<\/span><\/p>\n

Jeliko\u017e se v\u0161ak hl\u00e1s\u00ed pouze 6 a\u017e 10% ne\u017e\u00e1douc\u00edch reakc\u00ed (n\u011bkter\u00e9 zdroje uv\u00e1d\u011bj\u00ed, \u017ee dokonce pouze 1%), skute\u010dn\u00fd po\u010det ob\u011bt\u00ed by mohl b\u00fdt mnohem vy\u0161\u0161\u00ed. Beta-blok\u00e1tory maj\u00ed n\u00e1sleduj\u00edc\u00ed v\u00e1\u017en\u00e9 ne\u017e\u00e1douc\u00ed \u00fa\u010dinky:<\/span><\/p>\n