{"id":88207,"date":"2025-09-20T04:48:30","date_gmt":"2025-09-20T02:48:30","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=88207"},"modified":"2025-09-20T04:48:30","modified_gmt":"2025-09-20T02:48:30","slug":"dalsi-studie-potvrzuje-rezidualni-a-plazmidovou-dna-ve-vakcinach-proti-covidu","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2025\/09\/20\/dalsi-studie-potvrzuje-rezidualni-a-plazmidovou-dna-ve-vakcinach-proti-covidu\/","title":{"rendered":"Dal\u0161\u00ed studie potvrzuje rezidu\u00e1ln\u00ed a plazmidovou DNA ve vakc\u00edn\u00e1ch proti covidu"},"content":{"rendered":"
<\/div>\n

Slovensko\u00a0<\/span>se sna\u017eilo ve\u0159ejnost uklidnit<\/span><\/a>\u00a0, ale nov\u00e1 studie se op\u011bt zam\u011b\u0159ila na kontaminaci DNA v \u00fadajn\u011b bezpe\u010dn\u00fdch a dob\u0159e kontrolovan\u00fdch mRNA \u201evakc\u00edn\u00e1ch\u201c. V\u011bdci zjistili ve v\u0161ech testovan\u00fdch \u0161ar\u017e\u00edch mno\u017estv\u00ed zbytk\u016f DNA, kter\u00e9 daleko p\u0159ekra\u010dovalo platn\u00e9 limity. Byly tak\u00e9 nalezeny sekvence promotoru SV40, kter\u00e9 p\u0159edstavuj\u00ed bezpe\u010dnostn\u00ed riziko.<\/span><\/strong><\/p>\n

Komplexn\u00ed recenzovan\u00e1 studie z Kanady\/USA potvrzuje v\u00fdsledky publikace na\u0161eho t\u00fdmu MWGFD o detekci vysok\u00fdch koncentrac\u00ed DNA a plazmidov\u00fdch zbytk\u016f v \u0161ar\u017e\u00edch BioNTech\/Pfizer a Moderna<\/span><\/strong>\u00a0.<\/span><\/p>\n

Pr\u016flomovou publikaci s n\u00e1zvem\u00a0\u00a0<\/span>Kvantifikace<\/span><\/strong><\/a><\/em>\u00a0rezidu\u00e1ln\u00ed plazmidov\u00e9 DNA a sekvenc\u00ed promotor-enhancer SV40 ve vakc\u00edn\u00e1ch Pfizer\/BioNTech a Moderna modRNA proti COVID-19 z kanadsk\u00e9ho Ontaria<\/span><\/em>\u00a0ned\u00e1vno publikovali David Speicher, Jessica Rose a Kevin McKernan v \u010dasopise\u00a0\u00a0<\/span>Autoimmunity<\/span><\/em>\u00a0\u00a0[\u00a0 1]. Auto\u0159i popisuj\u00ed mno\u017estv\u00ed zbytk\u016f DNA (a\u017e 153n\u00e1sobek u Pfizeru a a\u017e 657n\u00e1sobek u Moderny) ve v\u0161ech zkouman\u00fdch \u0161ar\u017e\u00edch Comirnaty z Kanady (n=32), kter\u00e1 jsou v\u00fdrazn\u011b nad sou\u010dasn\u00fdmi limity pro \u201evolnou DNA\u201c, jako\u017e i dal\u0161\u00ed kritick\u00e9 slo\u017eky plazmidu v\u00fdrobce, zejm\u00e9na oblast promotor-enhancer SV40 souvisej\u00edc\u00ed s bezpe\u010dnost\u00ed \u2013 jak n\u00e1\u0161 t\u00fdm MWGFD dok\u00e1zal v recenzovan\u00e9 studii pro n\u011bmeck\u00e9 \u0161ar\u017ee Comirnaty na konci roku 2024 [2].<\/span><\/p>\n

Tato publikace na\u0161ich dvou \u010dlen\u016f (a dal\u0161\u00edho nez\u00e1visl\u00e9ho v\u011bdce) v\u0161ak byla po jej\u00edm zve\u0159ejn\u011bn\u00ed pomluvena autorem novin\u00e1\u0159sk\u00e9 reklamn\u00ed publikace se \u0161irok\u00fdm dosahem v laborato\u0159\u00edch [3]. Na\u0161i \u010dlenov\u00e9, kte\u0159\u00ed jsou uzn\u00e1van\u00fdmi molekul\u00e1rn\u00edmi biology s des\u00edtkami let praktick\u00fdch laboratorn\u00edch zku\u0161enost\u00ed, byli mimo jin\u00e9 ozna\u010deni za \u201epseudoexperty\u201c. Autor laboratorn\u00edho \u010dasopisu popsal metody pou\u017e\u00edvan\u00e9 na\u0161imi \u010dleny jako\u00a0\u00a0<\/span>\u201enevhodn\u00e9\u201c<\/span><\/em>\u00a0\u00a0pro detekci\u00a0\u00a0<\/span>\u201e\u00fadajn\u00e9 kontaminace DNA\u201c.<\/span><\/em>\u00a0\u00a0\u00a0P\u0159esn\u011b stejn\u00e9 metody v\u0161ak byly pou\u017eity i ve studii Speichera a koleg\u016f. Porovn\u00e1n\u00edm testovan\u00fdch \u0161ar\u017e\u00ed s publikovan\u00fdmi zpr\u00e1vami o ne\u017e\u00e1douc\u00edch \u00fa\u010dinc\u00edch byli auto\u0159i dokonce schopni prok\u00e1zat korelaci mezi mno\u017estv\u00edm detekovan\u00fdch zbytk\u016f DNA a \u010detnost\u00ed ne\u017e\u00e1douc\u00edch \u00fa\u010dink\u016f.<\/span><\/p>\n

Pokud jde o plazmidov\u00e9 slo\u017eky pou\u017eit\u00e9ho plazmidu v\u00fdrobce, kter\u00e9 poch\u00e1zej\u00ed z\u00a0\u00a0<\/span>\u201eprogramu genov\u00e9 terapie Pfizer<\/span><\/em> \u00a0\u201c, jak hrd\u011b popsali v\u011bdci spole\u010dnosti Pfizer v publikaci [4], je t\u0159eba poznamenat, \u017ee tyto slo\u017eky NEBYLY deklarov\u00e1ny v p\u016fvodn\u00edm ozn\u00e1men\u00ed regula\u010dn\u00edm org\u00e1n\u016fm. Tyto kritick\u00e9 slo\u017eky plazmidu byly spole\u010dnost\u00ed Pfizer \u201ep\u0159edlo\u017eeny\u201c a\u017e na konci ledna 2025, v\u00edce ne\u017e m\u011bs\u00edc po zve\u0159ejn\u011bn\u00ed na\u0161imi \u010dleny [2]. Dokument byl zve\u0159ejn\u011bn Evropskou agenturou pro l\u00e9\u010div\u00e9 p\u0159\u00edpravky (EMA) a\u017e 12. srpna 2025, shodou okolnost\u00ed kr\u00e1tce na \u017e\u00e1dost na\u0161eho p\u0159edsedy, prof. Haralda Walacha [5]. A\u010dkoli je v\u011bt\u0161ina dokumentu redigov\u00e1na, spole\u010dnost Pfizer ofici\u00e1ln\u011b potvrzuje, \u017ee prvky SV40 jsou skute\u010dn\u011b obsa\u017eeny v kone\u010dn\u00e9m produktu (Comirnaty) a \u017ee zbytkov\u00e1 DNA je jist\u011b zabalena spolu s modRNA v lipidov\u00fdch nano\u010d\u00e1stic\u00edch (LNP) \u2013 co\u017e \u010din\u00ed sou\u010dasn\u00fd limit pro volnou DNA zastaral\u00fdm. Dal\u0161\u00ed v\u00fdbu\u0161n\u00e9 prohl\u00e1\u0161en\u00ed, kter\u00e9 nen\u00ed zcela za\u010dern\u011bno, lze nal\u00e9zt v kapitole 8 na stran\u011b 16, zv\u00fdrazn\u011bno tu\u010dn\u011b n\u00ed\u017ee:<\/span><\/p>\n

\u201e\u00a0<\/span>8. Charakterizace sekven\u010dn\u00edch element\u016f SV40 v rezidu\u00e1ln\u00ed DNA\u201c<\/span><\/em><\/p>\n

Line\u00e1rn\u00ed templ\u00e1t DNA odvozen\u00fd z plazmidu pou\u017eit\u00fd jako v\u00fdchoz\u00ed materi\u00e1l pro synt\u00e9zu DS mRNA (<\/span>\u00a0pozn\u00e1mka: DS je zkratka pro \u201el\u00e9\u010divou l\u00e1tku\u00a0<\/span>\u201c,\u00a0<\/span>\u00a0tj. skute\u010dnou aktivn\u00ed slo\u017eku Comirnaty, modRNA)\u00a0<\/span>\u00a0vakc\u00edny Comirnaty obsahuje dal\u0161\u00ed prvky sekvence DNA b\u011b\u017en\u011b se vyskytuj\u00edc\u00ed ve v\u00edce\u00fa\u010delov\u00e9 plazmidov\u00e9 DNA, jako jsou geny rezistence na antibiotika a dal\u0161\u00ed prvky sekvence DNA, kter\u00e9 se nepou\u017e\u00edvaj\u00ed pro produkci DS mRNA. Mezi tyto typick\u00e9 prvky sekvence DNA pat\u0159\u00ed restrik\u010dn\u00ed a klonovac\u00ed m\u00edsta\u00a0\u00a0<\/span>, stejn\u011b jako sekvence, kter\u00e9 podporuj\u00ed transkripci a polyadenylaci v eukaryotick\u00fdch bu\u0148k\u00e1ch<\/span><\/strong>\u00a0, jako nap\u0159\u00edklad<\/span>\u00a0\u00a0\u2026<\/span><\/em><\/p>\n

Spole\u010dnost Pfizer t\u00edmto ve schvalovac\u00edch dokumentech ofici\u00e1ln\u011b potvrzuje, \u017ee nejen\u017ee je sekvence promotor-enhancer SV40, kter\u00e1 byla zpochyb\u0148ov\u00e1na jako \u201ekonspira\u010dn\u00ed teorie\u201c, skute\u010dn\u011b obsa\u017eena ve fin\u00e1ln\u00edm produktu genetick\u00e9 vakc\u00edny Comirnaty, a tedy injek\u010dn\u011b aplikov\u00e1na o\u010dkovan\u00fdm jedinc\u016fm, ale \u017ee pou\u017eit\u00fd \u201ev\u00edce\u00fa\u010delov\u00fd plazmid\u201c obsahuje dal\u0161\u00ed prvky, kter\u00e9 mohou b\u00fdt aktivn\u00ed v eukaryotech, a tedy i v lidsk\u00fdch bu\u0148k\u00e1ch. Vzhledem k tomu, \u017ee cel\u00fd proces v\u00fdroby vakc\u00edny Comirnaty prob\u00edh\u00e1 v E. coli \u2013 bakteri\u00edch, a tedy prokaryotech, nikoli eukaryotech \u2013 je t\u0159eba si polo\u017eit ot\u00e1zku, jak\u00e9 genov\u00e9 sekvence umo\u017e\u0148uj\u00edc\u00ed aktivn\u00ed regulaci gen\u016f v lidsk\u00fdch bu\u0148k\u00e1ch d\u011blaj\u00ed v t\u00e9to modRNA vakc\u00edn\u011b.<\/span><\/p>\n

Mo\u017en\u00e1 by \u201eskute\u010dn\u00ed experti\u201c z Laboratory Journal mohli vysv\u011btlit toto odhalen\u00ed spole\u010dnosti Pfizer a jeho dopad na miliony p\u0159\u00edjemc\u016f vakc\u00edny Comiraty?<\/span><\/p>\n

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Tento \u010dl\u00e1nek se poprv\u00e9 objevil na\u00a0<\/span>MWGFD<\/span><\/a>\u00a0\u2013 Autor: Prof. Klaus Steger<\/span><\/em><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

Zdroje:<\/span><\/h4>\n

[1] Speicher DJ, Rose J, McKernan K (2025) Kvantifikace zbytkov\u00e9 plazmidov\u00e9 DNA a sekvenc\u00ed promotor-enhancer SV40 ve vakc\u00edn\u00e1ch Pfizer\/BioNTech a Moderna modRNA proti COVID-19 z Ontaria, Kanada. Autoimmunity. 58:1, 2551517,\u00a0\u00a0<\/span>https:\/\/doi.org\/10.1080\/08916934.2025.2551517<\/span><\/a><\/p>\n

[2] K\u00e4mmerer U, Schulz V, Steger K (2024) Injekce proti COVID-19 na b\u00e1zi RNA od BioNTech obsahuj\u00ed velk\u00e9 mno\u017estv\u00ed zbytkov\u00e9 DNA v\u010detn\u011b sekvence promotoru\/enhanceru SV40. Science, Public Health Policy and the Law. 5:1-22.\u00a0\u00a0<\/span>https:\/\/publichealthpolicyjournal.com\/biontech-rna-based-covid-19-inject ions-contain-large-amounts-of-residual-dna-including-an-sv40-promoter-enhancer-sequence\/<\/span><\/a><\/p>\n

[3] M\u00fcller H (2025) Instrumentalizace v\u011bdy. s. 16 a d\u00e1le. in:\u00a0\u00a0<\/span>LJ_25_05.pdf<\/span><\/a><\/p>\n

[4] Thorn CR, Sharma D, Combs R, Bhujbal S, Romine J, Zheng X, Sunasara K, Badkar A (2022) Cesta \u017eivota – v\u00fdvoj vakc\u00edny proti COVID-19 od spole\u010dnosti Pfizer. Curr Opin Biotechnol 78:102803.\u00a0\u00a0<\/span>https:\/\/doi.org\/10.1016\/j.copbio.2022.102803 . [5] https:\/\/www.ema.europa.eu\/en\/documents\/other\/comirnaty-residual-dna-characterization-report_en.pdf<\/span><\/a><\/p>\n

\"\"<\/p>\n","protected":false},"excerpt":{"rendered":"

Slovensko\u00a0se sna\u017eilo ve\u0159ejnost uklidnit\u00a0, ale nov\u00e1 studie se op\u011bt zam\u011b\u0159ila na kontaminaci DNA v \u00fadajn\u011b…<\/p>\n","protected":false},"author":2,"featured_media":88208,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[895,839,651],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/88207"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=88207"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/88207\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/88208"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=88207"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=88207"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=88207"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}