{"id":88130,"date":"2025-09-19T00:32:34","date_gmt":"2025-09-18T22:32:34","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=88130"},"modified":"2025-09-18T18:20:20","modified_gmt":"2025-09-18T16:20:20","slug":"shingrix-vakcina-proti-pasovemu-oparu-vyznamne-zvysuje-riziko-onemocneni","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2025\/09\/19\/shingrix-vakcina-proti-pasovemu-oparu-vyznamne-zvysuje-riziko-onemocneni\/","title":{"rendered":"Shingrix: Vakc\u00edna proti p\u00e1sov\u00e9mu oparu v\u00fdznamn\u011b zvy\u0161uje riziko onemocn\u011bn\u00ed"},"content":{"rendered":"<div id=\"fb-root\"><\/div>\n<p><strong><span dir=\"auto\">Pokud o\u010dkov\u00e1n\u00ed v\u00fdznamn\u011b zvy\u0161uje riziko onemocn\u011bn\u00ed, vyvst\u00e1v\u00e1 ot\u00e1zka u\u017eite\u010dnosti takov\u00e9 injekce. To je jednozna\u010dn\u011b p\u0159\u00edpad vakc\u00edny proti p\u00e1sov\u00e9mu oparu \u201eShingrix\u201c od spole\u010dnosti GlaxoSmithKline. Nov\u00e1 studie vyvol\u00e1v\u00e1 rozruch.<\/span><\/strong><\/p>\n<p><span dir=\"auto\">Ned\u00e1vn\u00e1 studie v \u010dasopise Clinical Infectious Diseases s n\u00e1zvem \u201e\u00a0<\/span><a href=\"https:\/\/academic.oup.com\/cid\/advance-article\/doi\/10.1093\/cid\/ciaf473\/8250066?login=false\"><span dir=\"auto\">P\u0159echodn\u00e9 zv\u00fd\u0161en\u00e9 riziko p\u00e1sov\u00e9ho oparu po o\u010dkov\u00e1n\u00ed vakc\u00ednou Shingrix: Anal\u00fdza samostatn\u011b kontrolovan\u00fdch p\u0159\u00edpad\u016f<\/span><\/a><span dir=\"auto\"> \u201c op\u011bt podkop\u00e1v\u00e1 narativ o bezpe\u010dnosti vakc\u00edny. Vakc\u00edna Shingrix, kter\u00e1 m\u00e1 chr\u00e1nit star\u0161\u00ed lidi p\u0159ed p\u00e1sov\u00fdm oparem, zvy\u0161uje riziko vzniku onemocn\u011bn\u00ed v n\u00e1sleduj\u00edc\u00edch t\u0159ech t\u00fddnech jeden\u00e1ctin\u00e1sobn\u011b po prvn\u00ed d\u00e1vce. Studie tak ukazuje, \u017ee ve v\u00fdznamn\u00e9 \u010d\u00e1sti p\u0159\u00edpad\u016f o\u010dkov\u00e1n\u00ed ve skute\u010dnosti vyvol\u00e1 onemocn\u011bn\u00ed, kter\u00e9mu m\u00e1 p\u0159edch\u00e1zet.<\/span><\/p>\n<p><span dir=\"auto\">V\u00fdzkumn\u00edci pod veden\u00edm A. N. Shettyho vyhodnotili data z obdob\u00ed od ledna 2023 do dubna 2025 z jihov\u00fdchodn\u00ed Austr\u00e1lie. Analyzovali anamn\u00e9zy tis\u00edc\u016f pacient\u016f v modelu samokontrolovan\u00e9 s\u00e9rie p\u0159\u00edpad\u016f, ve kter\u00e9m ka\u017ed\u00e1 o\u010dkovan\u00e1 osoba slou\u017e\u00ed jako vlastn\u00ed kontrola. V\u00fdsledek je jasn\u00fd: U osob star\u0161\u00edch 65 let, kter\u00e9 dostaly prvn\u00ed d\u00e1vku vakc\u00edny Shingrix, se v\u00fdskyt p\u00e1sov\u00e9ho oparu v prvn\u00edch 21 dnech jeden\u00e1ctin\u00e1sobn\u011b zv\u00fd\u0161il ve srovn\u00e1n\u00ed se srovn\u00e1vac\u00edm obdob\u00edm. Tento efekt nebyl u mlad\u0161\u00edch dosp\u011bl\u00fdch detekovateln\u00fd. Po druh\u00e9 d\u00e1vce se riziko op\u011bt sn\u00ed\u017eilo \u2013 to v\u0161ak nem\u011bn\u00ed nic na skute\u010dnosti, \u017ee hlavn\u00ed c\u00edlov\u00e1 skupina vakc\u00edny je obzvl\u00e1\u0161t\u011b ohro\u017eena bezprost\u0159edn\u011b po pod\u00e1n\u00ed.<\/span><\/p>\n<figure class=\"wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter\">\n<div class=\"wp-block-embed__wrapper\">\n<div class=\"twitter-tweet twitter-tweet-rendered\"><iframe id=\"twitter-widget-0\" class=\"\" title=\"X P\u0159\u00edsp\u011bvek\" src=\"https:\/\/platform.twitter.com\/embed\/Tweet.html?dnt=true&amp;embedId=twitter-widget-0&amp;features=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%3D%3D&amp;frame=false&amp;hideCard=false&amp;hideThread=false&amp;id=1968045792775532759&amp;lang=cs&amp;origin=https%3A%2F%2Freport24.news%2Fshingrix-impfstoff-gegen-guertelrose-erhoeht-erkrankungsrisiko-deutlich%2F&amp;sessionId=714527a6619f9001f1f05f80e42cfb71754db484&amp;theme=light&amp;widgetsVersion=2615f7e52b7e0%3A1702314776716&amp;width=550px\" frameborder=\"0\" scrolling=\"no\" allowfullscreen=\"allowfullscreen\" data-tweet-id=\"1968045792775532759\" data-mce-fragment=\"1\"><\/iframe><\/div>\n<\/div>\n<\/figure>\n<p><span dir=\"auto\">Auto\u0159i studie se sna\u017e\u00ed ve\u0159ejnost uklidnit. Poukazuj\u00ed na to, \u017ee nebyl pozorov\u00e1n \u017e\u00e1dn\u00fd n\u00e1r\u016fst z\u00e1va\u017en\u00fdch komplikac\u00ed, jako je postherpetick\u00e1 neuralgie. Tento argument v\u0161ak selh\u00e1v\u00e1. Z\u00e1sadn\u00ed je, \u017ee vakc\u00edna v obdob\u00ed po prvn\u00ed d\u00e1vce masivn\u011b zvy\u0161uje riziko onemocn\u011bn\u00ed. Pro star\u0161\u00ed pacienty to neznamen\u00e1 ochranu, ale sp\u00ed\u0161e dodate\u010dn\u00e9 riziko.<\/span><\/p>\n<p><span dir=\"auto\">Ale to zdaleka nen\u00ed v\u0161e. Shingrix distribuuje farmaceutick\u00fd gigant GlaxoSmithKline, spole\u010dnost s dlouhou histori\u00ed soudn\u00edch spor\u016f a miliardov\u00fdch pokut. Nicm\u00e9n\u011b vakc\u00ednu od roku 2018 doporu\u010duje n\u011bmeck\u00fd St\u00e1l\u00fd v\u00fdbor pro o\u010dkov\u00e1n\u00ed pro osoby star\u0161\u00ed 60 let a je hrazena zdravotn\u00edmi poji\u0161\u0165ovnami. To znamen\u00e1, \u017ee ve\u0159ejn\u00e9 pen\u00edze plynou do produktu, kter\u00fd m\u016f\u017ee d\u011blat prav\u00fd opak toho, co slibuje.<\/span><\/p>\n<p><span dir=\"auto\">Vzorec je zn\u00e1m\u00fd: Nejprve jsou vakc\u00edny pod velk\u00fdm tlakem vtla\u010dov\u00e1ny na trh, pot\u00e9 odborn\u00edci zleh\u010duj\u00ed v\u00fdsledn\u00e9 probl\u00e9my statistick\u00fdmi dohady. V p\u0159\u00edpad\u011b vakc\u00edny Shingrix je vysv\u011btlen\u00ed z\u0159ejm\u00e9: Aktivace imunitn\u00edho syst\u00e9mu reaktivuje virus varicella zoster, kter\u00fd dormantuje v nervov\u00e9 tk\u00e1ni, a t\u00edm podporuje propuknut\u00ed p\u00e1sov\u00e9ho oparu. M\u00edsto otev\u0159en\u00e9 diskuse o tomto mechanismu je riziko odm\u00edt\u00e1no jako \u201edo\u010dasn\u00e9\u201c.<\/span><\/p>\n<p><span dir=\"auto\">Studie v\u0161ak jasn\u011b ukazuje, \u017ee se nejedn\u00e1 o okrajov\u00fd jev. P\u011btin\u00e1sobn\u00e9 zv\u00fd\u0161en\u00ed rizika onemocn\u011bn\u00ed je v\u00e1\u017en\u00fdm d\u016fsledkem, kter\u00fd zpochyb\u0148uje v\u0161echna doporu\u010den\u00ed v oblasti zdravotn\u00ed politiky. O\u010dkov\u00e1n\u00ed se neukazuje jako \u0159e\u0161en\u00ed, ale jako sou\u010d\u00e1st probl\u00e9mu. Vzhledem k t\u011bmto \u010d\u00edsl\u016fm vyvst\u00e1v\u00e1 ot\u00e1zka, jak dlouho se zdravotnick\u00e9 org\u00e1ny budou doporu\u010den\u00ed dr\u017eet.<\/span><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-1185\" src=\"http:\/\/www.infokuryr.cz\/n\/wp-content\/uploads\/2021\/04\/kuryr-podpis.png\" alt=\"\" width=\"84\" height=\"24\" \/><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"wp-image-86927 aligncenter\" src=\"http:\/\/www.infokuryr.cz\/n\/wp-content\/uploads\/2025\/09\/letak-volby-2025-konference-3-212x300.png\" alt=\"\" width=\"785\" height=\"1111\" srcset=\"https:\/\/www.infokuryr.cz\/n\/wp-content\/uploads\/2025\/09\/letak-volby-2025-konference-3-212x300.png 212w, https:\/\/www.infokuryr.cz\/n\/wp-content\/uploads\/2025\/09\/letak-volby-2025-konference-3-724x1024.png 724w, https:\/\/www.infokuryr.cz\/n\/wp-content\/uploads\/2025\/09\/letak-volby-2025-konference-3-768x1086.png 768w, https:\/\/www.infokuryr.cz\/n\/wp-content\/uploads\/2025\/09\/letak-volby-2025-konference-3-1086x1536.png 1086w, https:\/\/www.infokuryr.cz\/n\/wp-content\/uploads\/2025\/09\/letak-volby-2025-konference-3-1448x2048.png 1448w, https:\/\/www.infokuryr.cz\/n\/wp-content\/uploads\/2025\/09\/letak-volby-2025-konference-3-1024x1448.png 1024w\" sizes=\"(max-width: 785px) 100vw, 785px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pokud o\u010dkov\u00e1n\u00ed v\u00fdznamn\u011b zvy\u0161uje riziko onemocn\u011bn\u00ed, vyvst\u00e1v\u00e1 ot\u00e1zka u\u017eite\u010dnosti takov\u00e9 injekce. To je jednozna\u010dn\u011b p\u0159\u00edpad&#8230;<\/p>\n","protected":false},"author":2,"featured_media":88131,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[8315,9781,651,21],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/88130"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=88130"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/88130\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/88131"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=88130"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=88130"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=88130"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}