{"id":82239,"date":"2025-06-27T00:12:06","date_gmt":"2025-06-26T22:12:06","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=82239"},"modified":"2025-06-26T12:54:53","modified_gmt":"2025-06-26T10:54:53","slug":"proc-se-zda-ze-temer-vsechno-zpusobuje-rakovinu-funkce-ledvin-souvisi-s-rozvojem-rakoviny","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2025\/06\/27\/proc-se-zda-ze-temer-vsechno-zpusobuje-rakovinu-funkce-ledvin-souvisi-s-rozvojem-rakoviny\/","title":{"rendered":"Pro\u010d se zd\u00e1, \u017ee t\u00e9m\u011b\u0159 v\u0161echno zp\u016fsobuje rakovinu? Funkce ledvin souvis\u00ed s rozvojem rakoviny"},"content":{"rendered":"
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M\u00e1te n\u011bkdy pocit, \u017ee rakovinu zp\u016fsobuje t\u00e9m\u011b\u0159 v\u0161echno? Seznam mo\u017en\u00fdch a pravd\u011bpodobn\u00fdch karcinogen\u016f sestaven\u00fd institucemi, jako je Mezin\u00e1rodn\u00ed agentura pro v\u00fdzkum rakoviny (IARC), neust\u00e1le roste. Samotn\u00e1 expozice karcinogenu v\u0161ak \u010dasto nesta\u010d\u00ed k vyvol\u00e1n\u00ed rakoviny, co\u017e nazna\u010duje, \u017ee mus\u00ed b\u00fdt zapojeny i dal\u0161\u00ed p\u0159\u00ed\u010dinn\u00e9 faktory.<\/p>\n

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V m\u00e9m ned\u00e1vn\u00e9m \u010dl\u00e1nku, publikovan\u00e9m v \u010dasopise\u00a0<\/span>Cells<\/span><\/em>\u00a0, navrhuji hypot\u00e9zu: rakovinu mohou podporovat toxiny, kter\u00e9 zhor\u0161uj\u00ed funkci ledvin. N\u00e1zev:\u00a0<\/span>Karcinogeneze spojen\u00e1 s toxinovou nefropati\u00ed: Navrhovan\u00e1 mediace fosf\u00e1tovou toxicitou<\/span><\/em>\u00a0.<\/span><\/p>\n

Stru\u010dn\u011b \u0159e\u010deno, ledviny jsou sou\u010d\u00e1st\u00ed endokrinn\u00edho org\u00e1nov\u00e9ho syst\u00e9mu, kter\u00fd reguluje miner\u00e1l fosfor \u2013 konkr\u00e9tn\u011b fosf\u00e1t p\u0159ij\u00edman\u00fd z potravy. Ve sv\u00e9m \u010dl\u00e1nku demonstruji, \u017ee nadbytek fosf\u00e1t\u016f m\u016f\u017ee souviset s nekontrolovan\u00fdm r\u016fstem bun\u011bk, tj. s rakovinou. V\u011bt\u0161ina lid\u00ed dnes konzumuje dva a\u017e t\u0159ikr\u00e1t v\u00edce fosf\u00e1t\u016f, ne\u017e pot\u0159ebuje. To zat\u011b\u017euje ledviny, zvy\u0161uje riziko poruchy regulace fosf\u00e1t\u016f a vede k bun\u011b\u010dn\u00e9mu onemocn\u011bn\u00ed\u00a0zn\u00e1m\u00e9mu jako\u00a0<\/span>fosf\u00e1tov\u00e1 toxicita \u2013 potenci\u00e1ln\u00edmu spou\u0161t\u011b\u010di rakoviny.<\/span><\/strong><\/p>\n

Nejv\u011bt\u0161\u00edmi zdroji fosf\u00e1t\u016f ve strav\u011b jsou ml\u00e9\u010dn\u00e9 v\u00fdrobky, vejce, maso, ryby, dr\u016fbe\u017e, obiloviny, lu\u0161t\u011bniny a v\u0161echny pr\u016fmyslov\u011b zpracovan\u00e9 potraviny s p\u0159idan\u00fdm fosf\u00e1tem. Potraviny s ni\u017e\u0161\u00edm obsahem fosf\u00e1t\u016f \u2013 jako je ovoce, zelenina a rostlinn\u00e9 tuky \u2013 by m\u011bly ve strav\u011b p\u0159eva\u017eovat, aby se sn\u00ed\u017eilo riziko rakoviny (\u00a0<\/span>viz Modula\u010dn\u00ed faktory u rakoviny: Fosfor ve strav\u011b | SpringerLink<\/span><\/em>\u00a0).<\/span><\/p>\n

To znamen\u00e1, \u017ee jak\u00fdkoli toxin, kter\u00fd po\u0161kozuje ledviny \u2013 tzv.\u00a0<\/span>toxinov\u00e1 nefropatie<\/span><\/strong>\u00a0\u2013 by mohl zp\u016fsobit poruchu regulace fosf\u00e1t\u016f, co\u017e by vedlo k fosf\u00e1tov\u00e9 toxicit\u011b a t\u00edm zv\u00fd\u0161ilo riziko rakoviny. I p\u0159et\u00ed\u017een\u00ed\u00a0<\/span>netoxick\u00fdmi<\/span><\/em>\u00a0l\u00e1tkami m\u016f\u017ee zhor\u0161it funkci ledvin a nep\u0159\u00edmo p\u0159isp\u011bt k rozvoji rakoviny.<\/span><\/p>\n

Z\u00e1v\u011br:<\/strong> Je nal\u00e9hav\u011b zapot\u0159eb\u00ed v\u00fdzkumu, kter\u00fd by tuto hypot\u00e9zu d\u00e1le prozkoumal a l\u00e9pe pochopil roli ledvin a toxicity fosf\u00e1t\u016f ve v\u00fdvoji rakoviny.<\/span><\/p>\n

Od Dr. Rona Browna, PhD., zdravotnick\u00e9 v\u011bdy<\/em><\/p>\n<\/div>\n<\/div>\n

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Zdroj<\/a><\/span><\/h3>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

M\u00e1te n\u011bkdy pocit, \u017ee rakovinu zp\u016fsobuje t\u00e9m\u011b\u0159 v\u0161echno? Seznam mo\u017en\u00fdch a pravd\u011bpodobn\u00fdch karcinogen\u016f sestaven\u00fd institucemi,…<\/p>\n","protected":false},"author":2,"featured_media":70875,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[1503,1366,21],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/82239"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=82239"}],"version-history":[{"count":1,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/82239\/revisions"}],"predecessor-version":[{"id":82240,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/82239\/revisions\/82240"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/70875"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=82239"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=82239"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=82239"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}