{"id":79679,"date":"2025-05-27T00:12:41","date_gmt":"2025-05-26T22:12:41","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=79679"},"modified":"2025-05-26T08:00:33","modified_gmt":"2025-05-26T06:00:33","slug":"jak-ibuprofen-meni-zdrave-krvinky-na-nebezpecna-trnita-jablka","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2025\/05\/27\/jak-ibuprofen-meni-zdrave-krvinky-na-nebezpecna-trnita-jablka\/","title":{"rendered":"Jak ibuprofen m\u011bn\u00ed zdrav\u00e9 krvinky na nebezpe\u010dn\u00e1 \u201etrnit\u00e1 jablka\u201c"},"content":{"rendered":"
<\/div>\n

Bolest hlavy po dlouh\u00e9m dni v pr\u00e1ci. Bolest zad ze sportu. Rychl\u00e9 po\u017eit\u00ed ibuprofenu \u2013 to v\u00ed ka\u017ed\u00fd. Koneckonc\u016f, tato v\u011bc je pova\u017eov\u00e1na za ne\u0161kodnou a je k dost\u00e1n\u00ed voln\u011b v ka\u017ed\u00e9 l\u00e9k\u00e1rn\u011b. Ale co se vlastn\u011b v na\u0161em t\u011ble d\u011bje, kdy\u017e takovou tabletu spolkneme? Ned\u00e1vn\u00e1 studie nyn\u00ed ukazuje n\u011bco docela znepokojiv\u00e9ho: Tento \u0161iroce pou\u017e\u00edvan\u00fd l\u00e9k proti bolesti prom\u011b\u0148uje kulat\u00e9 zdrav\u00e9 krvinky v ostnat\u00e9 p\u0159\u00ed\u0161ery.<\/span><\/strong><\/p>\n

P\u0159edstavte si, \u017ee byste mohli cestovat sv\u00fdmi \u017eilami jako ve sci-fi filmu. Miliony \u010derven\u00fdch krvinek by kolem v\u00e1s prot\u00e9kaly \u2013 dokonal\u00e9 mal\u00e9 disky, kter\u00e9 vypadaj\u00ed jako drobn\u00e9 koblihy. Jen bez t\u00e9 d\u00edry uprost\u0159ed. Tento tvar je d\u016fmysln\u011b navr\u017een: bu\u0148ky se dok\u00e1\u017e\u00ed stla\u010dit jako houba a protla\u010dit se i t\u011bmi neju\u017e\u0161\u00edmi c\u00e9vami. Jakmile se tam dostanou, uvoln\u00ed cenn\u00fd kysl\u00edk a pou\u017eit\u00fd oxid uhli\u010dit\u00fd odvedou zp\u011bt do plic. V\u011b\u010dn\u00fd cyklus \u017eivota, milionkr\u00e1t za sekundu.<\/span><\/p>\n

Co d\u011bl\u00e1 \u010derven\u00e9 krvinky tak v\u00fdjime\u010dn\u00fdmi? Jsou neuv\u011b\u0159iteln\u011b flexibiln\u00ed. Stejn\u011b jako gumov\u00e9 m\u00ed\u010dky se deformuj\u00ed, p\u0159izp\u016fsobuj\u00ed a propl\u00e9taj\u00ed \u00fazk\u00fdmi prostory. Tato mobilita n\u00e1s udr\u017euje na\u017eivu \u2013 bez n\u00ed by na\u0161e tk\u00e1\u0148 zem\u0159ela b\u011bhem n\u011bkolika minut.<\/span><\/p>\n

Najednou rostou ostny<\/span><\/h3>\n

A pr\u00e1v\u011b zde p\u0159ich\u00e1z\u00ed na \u0159adu ibuprofen. V\u011bdci um\u00edstili l\u00e9k proti bolesti pod speci\u00e1ln\u00ed mikroskop \u2013 jak\u00fdsi 3D skener bun\u011bk. To, co vid\u011bli, bylo alarmuj\u00edc\u00ed. Jakmile se l\u00e9k dostal do kontaktu s krevn\u00edmi bu\u0148kami, za\u010daly se m\u011bnit. Ne pomalu cel\u00e9 hodiny, ale docela rychle. Z hladk\u00e9ho povrchu vyr\u016fstaly mal\u00e9 ostny, jako u je\u017eka nebo mo\u0159sk\u00e9ho je\u017eka. L\u00e9ka\u0159i naz\u00fdvaj\u00ed takov\u00e9 deformovan\u00e9 bu\u0148ky \u201ebu\u0148ky trnit\u00e9 jableky\u201c \u2013 n\u00e1zev \u0159\u00edk\u00e1 v\u0161e.<\/span><\/p>\n

Bu\u0148ky durmanu nejsou nic nov\u00e9ho. L\u00e9ka\u0159i je znaj\u00ed z r\u016fzn\u00fdch nemoc\u00ed. Nap\u0159\u00edklad p\u0159i srpkovit\u00e9 an\u00e9mii se \u010derven\u00e9 krvinky st\u00e1vaj\u00ed srpkovit\u011b tvarovan\u00fdmi a blokuj\u00ed c\u00e9vy. To m\u016f\u017ee b\u00fdt opravdu nebezpe\u010dn\u00e9 \u2013 po\u0161kozen\u00ed org\u00e1n\u016f, extr\u00e9mn\u00ed bolest, dokonce i smrt. K takov\u00fdm deformac\u00edm doch\u00e1z\u00ed tak\u00e9 v d\u016fsledku nespr\u00e1vn\u00e9ho skladov\u00e1n\u00ed krevn\u00edch produkt\u016f nebo n\u011bkter\u00fdch onemocn\u011bn\u00ed jater.<\/span><\/p>\n

N\u00edzk\u00e1 d\u00e1vka \u2013 \u017e\u00e1dn\u00fd probl\u00e9m?<\/span><\/h3>\n

Na\u0161t\u011bst\u00ed ne ka\u017ed\u00e1 tableta ibuprofenu je pro na\u0161e krevn\u00ed bu\u0148ky rozsudkem smrti. P\u0159i norm\u00e1ln\u00edch d\u00e1vk\u00e1ch se deformovan\u00e9 bu\u0148ky mohou zotavit. Hroty zmiz\u00ed a vr\u00e1t\u00ed se p\u016fvodn\u00ed tvar koblihy. Zat\u00edm uklid\u0148uj\u00edc\u00ed. Ale \u2013 a to je velk\u00e9 ale \u2013 p\u0159i vy\u0161\u0161\u00edch koncentrac\u00edch se to st\u00e1v\u00e1 kritick\u00fdm.<\/span><\/p>\n

V\u011bdci testovali r\u016fzn\u00e9 d\u00e1vky. U 800, 1200 a 2400 miligram\u016f z\u00e1bava skon\u010dila. \u201eSchopnost \u010derven\u00fdch krvinek vr\u00e1tit se do tvaru podobn\u00e9ho koblize byla inhibov\u00e1na pouze p\u0159i vysok\u00fdch d\u00e1vk\u00e1ch ibuprofenu,\u201c\u00a0<\/span>p\u00ed\u0161\u00ed ve sv\u00e9 studii<\/span><\/a>\u00a0. Nikdo by nem\u011bl toto mno\u017estv\u00ed polykat bez l\u00e9ka\u0159sk\u00e9ho dohledu. P\u0159esto se to st\u00e1v\u00e1 \u010dast\u011bji, ne\u017e si mysl\u00edte.<\/span><\/p>\n

Probl\u00e9m se samol\u00e9\u010dbou<\/span><\/h3>\n

Tady je h\u00e1\u010dek. Ibuprofen je dostupn\u00fd bez l\u00e9ka\u0159sk\u00e9ho p\u0159edpisu a lze jej zakoupit t\u00e9m\u011b\u0159 v\u0161ude. Mnoho lid\u00ed si mysl\u00ed: Pokud je to voln\u011b prodejn\u00e9, nem\u016f\u017ee to u\u0161kodit. Osudov\u00e1 chyba. P\u0159i p\u0159etrv\u00e1vaj\u00edc\u00edch bolestech hlavy n\u011bkte\u0159\u00ed lid\u00e9 jednodu\u0161e u\u017e\u00edvaj\u00ed dvojn\u00e1sobnou d\u00e1vku. Nebo kombinuj\u00ed r\u016fzn\u00e9 p\u0159\u00edpravky, ani\u017e by v\u011bd\u011bli, \u017ee v\u0161echny obsahuj\u00ed ibuprofen. \u201eSkute\u010dnost, \u017ee ibuprofen je voln\u011b prodejn\u00fd l\u00e9k proti bolesti, zvy\u0161uje riziko p\u0159ed\u00e1vkov\u00e1n\u00ed,\u201c varuj\u00ed v\u011bdci. Opr\u00e1vn\u011bn\u00e1 obava.<\/span><\/p>\n

Obzvl\u00e1\u0161t\u011b podn\u011btn\u00e9 je, \u017ee mnoho lid\u00ed nem\u00e1 tu\u0161en\u00ed, jak\u00e9 n\u00e1sledky m\u016f\u017ee m\u00edt p\u0159ed\u00e1vkov\u00e1n\u00ed. Ka\u017ed\u00fd zn\u00e1 bolest b\u0159icha jako vedlej\u0161\u00ed \u00fa\u010dinek. Ale \u017ee ta l\u00e1tka deformuje na\u0161e krevn\u00ed bu\u0148ky? Jen velmi m\u00e1lo lid\u00ed o tom kdy sly\u0161elo.<\/span><\/p>\n

Co to pro n\u00e1s znamen\u00e1?<\/span><\/h3>\n

Tento objev pravd\u011bpodobn\u011b nezm\u011bn\u00ed sv\u011bt medic\u00edny p\u0159es noc. Ibuprofen z\u016fst\u00e1v\u00e1 d\u016fle\u017eit\u00fdm a \u010dasto nezbytn\u00fdm l\u00e9kem. Studie ale ukazuje, \u017ee i ne\u0161kodn\u011b vypadaj\u00edc\u00ed l\u00e9ky mohou vyvolat pom\u011brn\u011b drastick\u00e9 zm\u011bny na bun\u011b\u010dn\u00e9 \u00farovni. Mo\u017en\u00e1 to povede k lep\u0161\u00edm doporu\u010den\u00edm d\u00e1vkov\u00e1n\u00ed nebo k v\u00fdvoji bezpe\u010dn\u011bj\u0161\u00edch alternativ.<\/span><\/p>\n

Jedna v\u011bc se uk\u00e1zala jako jasn\u00e1: \u00facta k l\u00e9k\u016fm \u2013 i t\u011bm voln\u011b prodejn\u00fdm \u2013 je na m\u00edst\u011b. Rychl\u00fd dosah tabletu je t\u0159eba pe\u010dliv\u011b zv\u00e1\u017eit. N\u011bkdy m\u016f\u017ee stejn\u011b dob\u0159e pomoci sklenice vody, trochu odpo\u010dinku nebo proch\u00e1zka. A pokud opravdu mus\u00edte pou\u017e\u00edt l\u00e9ky proti bolesti, pou\u017e\u00edvejte je pros\u00edm rozumn\u011b a s m\u00edrou.<\/span><\/p>\n

\"\"<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Bolest hlavy po dlouh\u00e9m dni v pr\u00e1ci. Bolest zad ze sportu. Rychl\u00e9 po\u017eit\u00ed ibuprofenu \u2013…<\/p>\n","protected":false},"author":2,"featured_media":79680,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[9193,9108,1020],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/79679"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=79679"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/79679\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/79680"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=79679"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=79679"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=79679"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}