{"id":76456,"date":"2025-04-16T00:12:20","date_gmt":"2025-04-15T22:12:20","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=76456"},"modified":"2025-04-15T12:33:24","modified_gmt":"2025-04-15T10:33:24","slug":"nova-studie-mladi-dospeli-zjevne-produkuji-toxicky-spike-protein-po-dobu-jednoho-roku-po-injekci-mrna-covid-19","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2025\/04\/16\/nova-studie-mladi-dospeli-zjevne-produkuji-toxicky-spike-protein-po-dobu-jednoho-roku-po-injekci-mrna-covid-19\/","title":{"rendered":"Nov\u00e1 studie: Mlad\u00ed dosp\u011bl\u00ed zjevn\u011b produkuj\u00ed toxick\u00fd spike protein po dobu jednoho roku po injekci mRNA COVID-19"},"content":{"rendered":"<div id=\"fb-root\"><\/div>\n<div class=\"elementor-element elementor-element-1fb4c2c elementor-widget elementor-widget-theme-post-content\" data-id=\"1fb4c2c\" data-element_type=\"widget\" data-widget_type=\"theme-post-content.default\">\n<div class=\"elementor-widget-container\">\n<p>Nov\u00e1 longitudin\u00e1ln\u00ed studie publikovan\u00e1 v \u010dasopise\u00a0<em>Immunity, Inflammation and Disease<\/em>\u00a0ukazuje, \u017ee mlad\u00ed dosp\u011bl\u00ed maj\u00ed v\u00fdznamn\u011b zv\u00fd\u0161en\u00e9 hladiny z\u00e1n\u011btu i v\u00edce ne\u017e jeden rok po o\u010dkov\u00e1n\u00ed mRNA. Podle v\u00fdzkumn\u00edk\u016f to ukazuje na\u00a0<strong>trvalou produkci spike proteinu<\/strong>\u00a0a\u00a0<strong>chronickou imunitn\u00ed stimulaci<\/strong>\u00a0\u2013 s potenci\u00e1ln\u011b dalekos\u00e1hl\u00fdmi zdravotn\u00edmi n\u00e1sledky.<\/p>\n<h3 class=\"wp-block-heading\"><strong>Pozad\u00ed a metoda<\/strong><\/h3>\n<p>Studie nazvan\u00e1\u00a0<em>Profil zm\u011bn\u011bn\u00fdch cirkuluj\u00edc\u00edch cytokin\u016f mezi mlad\u00fdmi dosp\u011bl\u00fdmi o\u010dkovan\u00fdmi mRNA<\/em>\u00a0zkoumala 84 sa\u00fadsk\u00fdch subjekt\u016f (pr\u016fm\u011brn\u00fd v\u011bk: 27,2 let) po dobu 13 a\u017e 14 m\u011bs\u00edc\u016f po jejich prvn\u00edm o\u010dkov\u00e1n\u00ed mRNA COVID-19. Krevn\u00ed hodnoty, antropometrick\u00e1 data a cytokinov\u00e9 profily byly shrom\u00e1\u017ed\u011bny pomoc\u00ed standardizovan\u00fdch laboratorn\u00edch test\u016f.<\/p>\n<h3 class=\"wp-block-heading\"><strong>Kl\u00ed\u010dov\u00e9 v\u00fdsledky<\/strong><\/h3>\n<ul>\n<li><strong>V\u00fdznamn\u011b zv\u00fd\u0161en\u00e9 hladiny cytokin\u016f<\/strong>\u00a0b\u011bhem jednoho roku po o\u010dkov\u00e1n\u00ed:<\/li>\n<\/ul>\n<ul style=\"list-style-type: circle;\">\n<li>TNF-a, IL-lp, IL-6, IL-4, IL-7, IL-17E (proz\u00e1n\u011btliv\u00e9)<\/li>\n<li>VEGFA, FGF2, IFN-\u03b3 (remodelace c\u00e9v, reparace tk\u00e1n\u00ed)<\/li>\n<li>MCP-1, MCP-3 (chronick\u00fd z\u00e1n\u011bt, autoimunita)<\/li>\n<\/ul>\n<ul>\n<li><strong>Pouze jeden cytokin (MCSF)<\/strong>\u00a0byl v\u00fdznamn\u011b sn\u00ed\u017een \u2013 indikace mo\u017en\u00e9\u00a0<strong>imunitn\u00ed dysregulace<\/strong>\u00a0.<\/li>\n<li><strong>Rozd\u00edly podle pohlav\u00ed a v\u011bku<\/strong>\u00a0:<\/li>\n<\/ul>\n<ul style=\"list-style-type: circle;\">\n<li>Mu\u017ei vykazovali v\u011bt\u0161\u00ed zv\u00fd\u0161en\u00ed IL-6, IL-4 a TNF-\u03b1.<\/li>\n<li>Star\u0161\u00ed \u00fa\u010dastn\u00edci vykazovali vy\u0161\u0161\u00ed hladiny EGF, IL-6, MCP-1, TNF-\u03b1.<\/li>\n<li>Mlad\u0161\u00ed lid\u00e9 maj\u00ed naopak vy\u0161\u0161\u00ed hladiny VEGFA \u2013 markeru vaskul\u00e1rn\u00ed aktivace.<\/li>\n<\/ul>\n<h3 class=\"wp-block-heading\"><strong>Z\u00e1v\u011br autor\u016f<\/strong><\/h3>\n<p>V\u00fdsledky nazna\u010duj\u00ed\u00a0<strong>trvalou imunitn\u00ed aktivaci zprost\u0159edkovanou proteinem<\/strong>\u00a0, pravd\u011bpodobn\u011b kv\u016fli dv\u011bma hlavn\u00edm faktor\u016fm:<\/p>\n<ol>\n<li><strong>Modifikovan\u00e1, nukleosidy stabilizovan\u00e1 mRNA<\/strong>\u00a0, kter\u00e1 z\u016fst\u00e1v\u00e1 v t\u011ble d\u00e9le, ne\u017e se o\u010dek\u00e1valo<\/li>\n<li><strong>Proz\u00e1n\u011btliv\u00e9 lipidov\u00e9 nano\u010d\u00e1stice<\/strong>\u00a0, kter\u00e9 jsou distribuov\u00e1ny syst\u00e9mov\u011b<\/li>\n<\/ol>\n<p>Tato kombinace by mohla podporovat chronick\u00e9 z\u00e1n\u011btliv\u00e9 stavy a v\u00e9st k\u00a0<strong>autoimunitn\u00edm onemocn\u011bn\u00edm, po\u0161kozen\u00ed c\u00e9v a dlouhotrvaj\u00edc\u00edm postvakcina\u010dn\u00edm syndrom\u016fm<\/strong>\u00a0.<\/p>\n<h3 class=\"wp-block-heading\"><strong>Klasifikace podle autora<\/strong><\/h3>\n<p>Nicolas Hulscher, MPH (McCullough Foundation), poukazuje na v\u00edce ne\u017e\u00a0<strong>130 recenzovan\u00fdch studi\u00ed<\/strong>\u00a0dokumentuj\u00edc\u00edch podobn\u00e1 rizika \u2013 v\u010detn\u011b:<\/p>\n<ul>\n<li><strong>Syst\u00e9mov\u00e1 distribuce mRNA<\/strong><\/li>\n<li><strong>Dlouhodob\u00e1 perzistence mRNA a spike proteinu<\/strong><\/li>\n<li><strong>Toxicita pou\u017eit\u00e9ho nosn\u00e9ho syst\u00e9mu lipidov\u00fdch nano\u010d\u00e1stic<\/strong><\/li>\n<\/ul>\n<p>S ohledem na dostupn\u00e1 data po\u017eaduje, aby\u00a0<strong>byly mRNA vakc\u00edny urychlen\u011b sta\u017eeny z trhu<\/strong>\u00a0.<\/p>\n<\/div>\n<\/div>\n<div class=\"elementor-element elementor-element-8c57238 quelle dc-has-condition dc-condition-empty elementor-widget elementor-widget-heading\" data-id=\"8c57238\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n<div class=\"elementor-widget-container\">\n<h3 class=\"elementor-heading-title elementor-size-default\"><span style=\"font-size: 10pt;\"><a href=\"https:\/\/www.thefocalpoints.com\/p\/new-study-young-adults-likely-produce\" target=\"_blank\" rel=\"nofollow noopener\">Zdroj<\/a><\/span><\/h3>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Nov\u00e1 longitudin\u00e1ln\u00ed studie publikovan\u00e1 v \u010dasopise\u00a0Immunity, Inflammation and Disease\u00a0ukazuje, \u017ee mlad\u00ed dosp\u011bl\u00ed maj\u00ed v\u00fdznamn\u011b zv\u00fd\u0161en\u00e9&#8230;<\/p>\n","protected":false},"author":2,"featured_media":76457,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[694,8650,839,651],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/76456"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=76456"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/76456\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/76457"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=76456"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=76456"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=76456"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}