{"id":72702,"date":"2025-02-20T00:15:42","date_gmt":"2025-02-19T23:15:42","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=72702"},"modified":"2025-02-19T14:17:26","modified_gmt":"2025-02-19T13:17:26","slug":"vyrobeno-v-laboratori-ai-odhaluje-puvod-covid-19","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2025\/02\/20\/vyrobeno-v-laboratori-ai-odhaluje-puvod-covid-19\/","title":{"rendered":"Vyrobeno v laborato\u0159i: AI odhaluje p\u016fvod COVID-19"},"content":{"rendered":"
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Je to slo\u017eit\u00e9. Konkr\u00e9tn\u00ed recept um\u011bl\u00e9 inteligence na COVID-19 u\u017e mo\u017en\u00e1 nikdy nebude nalezen, ale pomoc\u00ed jin\u00fdch technik um\u011bl\u00e9 inteligence lze virus do ur\u010dit\u00e9 m\u00edry reverzn\u011b zpracovat. Nyn\u00ed v\u0161ak existuje dostatek d\u016fkaz\u016f, kter\u00e9 nazna\u010duj\u00ed, \u017ee COVID-19 byla sofistikovan\u00e1, laboratorn\u011b vyroben\u00e1 biologick\u00e1 zbra\u0148.
\n\u2043 Patrick Wood, redaktor<\/em><\/p>\n

P\u0159ekvapiv\u00fd objev o p\u016fvodu COVID-19<\/strong><\/h2>\n

Nov\u00e1, neo\u010dek\u00e1van\u00e1 studie nazna\u010duje, \u017ee COVID-19 nemus\u00ed m\u00edt p\u016fvod v netop\u00fdrech nebo pangol\u00ednech, ale vznikl ze vz\u00e1cn\u00e9 f\u00faze lidsk\u00fdch nemoc\u00ed.<\/p>\n

V\u011bdci pou\u017eili pokro\u010dil\u00fd p\u0159\u00edstup zalo\u017een\u00fd na um\u011bl\u00e9 inteligenci nazvan\u00fd\u00a0Max-Logistic Intelligence<\/em>\u00a0k identifikaci genetick\u00fdch vazeb mezi COVID-19 a dv\u011bma m\u00e1lo zn\u00e1m\u00fdmi infekcemi \u2013 vozh\u0159ivka a hore\u010dka Sennetsu. Tento objev by mohl z\u00e1sadn\u011b p\u0159epsat historii p\u016fvodu viru.<\/p>\n

Dek\u00f3dov\u00e1n\u00ed p\u016fvodu COVID-19<\/strong><\/h2>\n

P\u0159es rozs\u00e1hl\u00fd v\u00fdzkum z\u016fst\u00e1v\u00e1 p\u016fvod COVID-19 nejasn\u00fd. Nov\u00e1 studie publikovan\u00e1 v\u00a0Advances in Biomarker Science and Technology (ABST)<\/em>\u00a0vyu\u017e\u00edv\u00e1 p\u0159\u00edstup \u0159\u00edzen\u00fd um\u011blou inteligenc\u00ed k\u00a0anal\u00fdze vzorc\u016f metylace DNA na\u00a0865 859 m\u00edstech CpG ve vzorc\u00edch krve pacient\u016f s COVID-19 v ran\u00fdch st\u00e1di\u00edch onemocn\u011bn\u00ed.<\/strong><\/p>\n

Studie\u00a0veden\u00e1\u00a0Zhengjunem Zhangem<\/strong>\u00a0z katedry statistiky\u00a0University of Wisconsin pou\u017eila\u00a0<\/strong>Max-Logistic Intelligence<\/em>\u00a0k identifikaci siln\u00fdch genetick\u00fdch vazeb. V\u00fdsledky nazna\u010duj\u00ed, \u017ee COVID-19 mohl vzniknout p\u0159irozen\u00fdm spojen\u00edm dvou vz\u00e1cn\u00fdch infek\u010dn\u00edch onemocn\u011bn\u00ed \u2013\u00a0vozh\u0159ivky a hore\u010dky Sennetsu<\/strong>\u00a0\u2013 v kombinaci s b\u011b\u017en\u00fdmi lidsk\u00fdmi nemocemi.<\/p>\n

P\u0159ehodnocen\u00ed na\u0161eho p\u016fvodu ve sv\u011bt\u011b zv\u00ed\u0159at?<\/strong><\/h2>\n

Tato zji\u0161t\u011bn\u00ed zpochyb\u0148uj\u00ed b\u011b\u017enou teorii, \u017ee virus poch\u00e1z\u00ed z netop\u00fdr\u016f nebo luskoun\u016f. Nazna\u010duj\u00ed, \u017ee p\u0159edchoz\u00ed studie se mohly p\u0159\u00edli\u0161 soust\u0159edit na p\u016fvod u divok\u00fdch zv\u00ed\u0159at.<\/p>\n

\u201ePropojen\u00ed\u00a0865 859 m\u00edst CpG<\/strong>\u00a0je obrovskou v\u00fdzvou, proto\u017ee n\u00e1hodn\u00e9 korelace se vyskytuj\u00ed s pravd\u011bpodobnost\u00ed men\u0161\u00ed ne\u017e\u00a0jedna ku deseti milion\u016fm<\/strong>\u00a0,\u201c vysv\u011btluje Zhang. „Kdy\u017e v\u0161ak vezmete v \u00favahu vz\u00e1cnost t\u011bchto onemocn\u011bn\u00ed, pravd\u011bpodobnost objeven\u00ed smyslupln\u00e9 souvislosti klesne na\u00a0jednu ku sto milion\u016fm<\/strong>\u00a0– co\u017e d\u00e1le posiluje platnost na\u0161ich v\u00fdsledk\u016f.“<\/p>\n

Max-Logistic Intelligence: Pr\u016flom?<\/strong><\/h2>\n

Max-Logistic Intelligence<\/em>\u00a0ji\u017e byla pou\u017eita ve studi\u00edch biomarker\u016f rakoviny. Ve srovn\u00e1n\u00ed s tradi\u010dn\u00edmi algoritmy AI nebo modern\u00edmi metodami strojov\u00e9ho u\u010den\u00ed, jako jsou\u00a0n\u00e1hodn\u00e9 lesy, hlubok\u00e9 u\u010den\u00ed a podp\u016frn\u00e9 vektorov\u00e9 stroje,<\/strong>\u00a0nab\u00edz\u00ed tato metoda\u00a0vy\u0161\u0161\u00ed interpretovatelnost, konzistenci a robustnost<\/strong>\u00a0, zejm\u00e9na p\u0159i identifikaci kauz\u00e1ln\u00edch vztah\u016f.<\/p>\n

Zhang zd\u016fraz\u0148uje, \u017ee zat\u00edmco identifikace spolehliv\u00fdch biomarker\u016f je z\u00e1sadn\u00ed pro v\u011bdeck\u00fd pokrok, mnoho genetick\u00fdch marker\u016f objeven\u00fdch v izolovan\u00fdch studi\u00edch nen\u00ed reprodukovateln\u00fdch v jin\u00fdch kohort\u00e1ch, tak\u017ee mezi skupinami \u010dasto existuje jen mal\u00e1 shoda.<\/p>\n

“\u00a0DNA metylace<\/strong>\u00a0, p\u0159id\u00e1n\u00ed methylov\u00fdch skupin k DNA, hraje \u00fast\u0159edn\u00ed roli v\u00a0genov\u00e9 expresi<\/strong>\u00a0a\u00a0rozvoji onemocn\u011bn\u00ed<\/strong>\u00a0,“ vysv\u011btluje Zhang. „Dysregulace v tomto procesu m\u016f\u017ee zp\u016fsobit onemocn\u011bn\u00ed – jeden z d\u016fvod\u016f, pro\u010d jsme se bl\u00ed\u017ee pod\u00edvali na vzorce metylace DNA COVID-19.“<\/p>\n

Odkaz<\/strong><\/h2>\n

\u201eEtiologick\u00e9 souvislosti mezi p\u016fvodn\u00edm COVID-19 a dv\u011bma vz\u00e1cn\u00fdmi infek\u010dn\u00edmi nemocemi\u201c<\/em>\u00a0\u2013\u00a0Zhengjun Zhang<\/strong>\u00a0, publikovan\u00e9\u00a09. prosince 2024<\/strong>\u00a0v\u00a0Advances in Biomarker Science and Technology.<\/em><\/p>\n<\/div>\n<\/div>\n

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Zdroj<\/a><\/span><\/h3>\n

 <\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Je to slo\u017eit\u00e9. Konkr\u00e9tn\u00ed recept um\u011bl\u00e9 inteligence na COVID-19 u\u017e mo\u017en\u00e1 nikdy nebude nalezen, ale…<\/p>\n","protected":false},"author":2,"featured_media":19792,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[3101,593,1361,3337,839],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/72702"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=72702"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/72702\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/19792"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=72702"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=72702"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=72702"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}