{"id":69162,"date":"2024-12-30T05:57:33","date_gmt":"2024-12-30T04:57:33","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=69162"},"modified":"2024-12-30T05:57:33","modified_gmt":"2024-12-30T04:57:33","slug":"uzasne-zdravotni-prinosy-bylinky-ruty-vonave-pro-nas-mozek","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2024\/12\/30\/uzasne-zdravotni-prinosy-bylinky-ruty-vonave-pro-nas-mozek\/","title":{"rendered":"\u00da\u017easn\u00e9 zdravotn\u00ed p\u0159\u00ednosy bylinky ruty vo\u0148av\u00e9 pro n\u00e1\u0161 mozek"},"content":{"rendered":"
<\/div>\n

P\u0159i hled\u00e1n\u00ed \u0159e\u0161en\u00ed neurodegenerativn\u00edch chorob, jako jsou Alzheimerova, Huntingtonova nebo Parkinsonova choroba, v\u011bdci zkoumaj\u00ed p\u0159\u00edrodn\u00ed sv\u011bt, aby se v n\u011bm inspirovali.<\/strong><\/p>\n

Jedna rostlinka, kter\u00e1 na tomto poli pout\u00e1 zna\u010dnou pozornost, je ruta vo\u0148av\u00e1 (lat. Ruta graveolens), k\u0159ovit\u00e1 bylina poch\u00e1zej\u00edc\u00ed z oblasti St\u0159edozemn\u00edho mo\u0159e.<\/span><\/p>\n

Ruta se v tradi\u010dn\u00ed medic\u00edn\u011b ji\u017e cel\u00e1 stalet\u00ed slav\u00ed pro sv\u00e9 rozmanit\u00e9 l\u00e9\u010div\u00e9 vlastnosti, kde se pou\u017e\u00edv\u00e1 k l\u00e9\u010db\u011b nemoc\u00ed od bolesti a ko\u017en\u00edch stav\u016f a\u017e po neurologick\u00e9 poruchy, jako je roztrou\u0161en\u00e1 skler\u00f3za.<\/span><\/p>\n

Dnes v\u011bdci zkoumaj\u00ed jej\u00ed potenci\u00e1l podporovat a obnovovat zdrav\u00ed a funkci mozku.<\/span><\/p>\n

V\u00fdzkumn\u00edci se zam\u011b\u0159uj\u00ed na vliv ruty vo\u0148av\u00e9 na centr\u00e1ln\u00ed nervov\u00fd syst\u00e9m s c\u00edlem odhalit, jak jej\u00ed chemick\u00e9 slou\u010deniny podporuj\u00ed zdrav\u00ed mozku a bojuj\u00ed proti mechanism\u016fm, kter\u00e9 stoj\u00ed za mozek oslabuj\u00edc\u00edmi chorobami.<\/span><\/p>\n

Za sv\u016fj potenci\u00e1l vd\u011b\u010d\u00ed tato bylinka siln\u00e9mu metabolitu zvan\u00e9mu \u201erutin\u201c. Rutin, objeven\u00fd v roce 1936 a n\u011bkdy ozna\u010dovan\u00fd jako vitam\u00edn P, je flavonoid zn\u00e1m\u00fd pro sv\u00e9 antioxida\u010dn\u00ed a protiz\u00e1n\u011btliv\u00e9 vlastnosti.<\/span><\/p>\n

Uveden\u00e9 atributy d\u011blaj\u00ed z rutinu slibn\u00e9ho kandid\u00e1ta na \u0159e\u0161en\u00ed oxida\u010dn\u00edho stresu a z\u00e1n\u011btu spojen\u00e9ho s neurodegenerativn\u00edmi onemocn\u011bn\u00edmi. Krom\u011b toho bylo zji\u0161t\u011bno, \u017ee rutin inhibuje \u0161kodliv\u00e9 enzymy, chr\u00e1n\u00ed neurony p\u0159ed toxiny a podporuje p\u0159e\u017eit\u00ed mozkov\u00fdch bun\u011bk.<\/span><\/p>\n

1. Alzheimerova choroba<\/span><\/h2>\n

Alzheimerova choroba je charakterizov\u00e1na ztr\u00e1tou pam\u011bti a kognitivn\u00edm poklesem, \u010d\u00e1ste\u010dn\u011b zp\u016fsoben\u00fdm smrt\u00ed cholinergn\u00edch neuron\u016f a hromad\u011bn\u00edm \u0161kodliv\u00fdch beta-amyloidn\u00edch plak\u016f.<\/span><\/p>\n

Ruta a jej\u00ed rutin se uk\u00e1zaly jako pom\u011brn\u011b slibn\u00e9 v boji proti t\u011bmto \u00fa\u010dink\u016fm, nebo\u0165 zvy\u0161uj\u00ed hladinu acetylcholinu. Ruta p\u016fsob\u00ed jako inhibitor acetylcholinester\u00e1zy (AChE) a pom\u00e1h\u00e1 udr\u017eovat hladiny acetylcholinu, neurotransmiteru \u017eivotn\u011b d\u016fle\u017eit\u00e9ho pro u\u010den\u00ed a pam\u011b\u0165.<\/span><\/p>\n

Tento mechanismus je podobn\u00fd mechanismu l\u00e9k\u016f, jako je donepezil, ale bez gastrointestin\u00e1ln\u00edch vedlej\u0161\u00edch \u00fa\u010dink\u016f, kter\u00e9 se u t\u011bchto l\u00e9k\u016f \u010dasto vyskytuj\u00ed.<\/span><\/p>\n

D\u00e1le bojuje proti plak\u016fm a z\u00e1n\u011bt\u016fm. Studie ukazuj\u00ed, \u017ee rutin sni\u017euje beta-amyloidn\u00ed plaky na zv\u00ed\u0159ec\u00edch modelech a z\u00e1rove\u0148 sni\u017euje z\u00e1n\u011btliv\u00e9 faktory jako nap\u0159\u00edklad proz\u00e1n\u011btliv\u00e9 cytokiny.<\/span><\/p>\n

Toto dvoj\u00ed p\u016fsoben\u00ed by mohlo zpomalit progresi onemocn\u011bn\u00ed a zlep\u0161it p\u0159e\u017eit\u00ed neuron\u016f.<\/span><\/p>\n

Ruta tak\u00e9 zlep\u0161uje pam\u011b\u0165. Studie na zv\u00ed\u0159atech nazna\u010duj\u00ed, \u017ee rutin podporuje u\u010den\u00ed a pam\u011b\u0165 \u2013 pravd\u011bpodobn\u011b d\u00edky sv\u00fdm protiz\u00e1n\u011btliv\u00fdm a antioxida\u010dn\u00edm \u00fa\u010dink\u016fm. M\u016f\u017ee tak\u00e9 aktivovat mikrogli\u00e1ln\u00ed bu\u0148ky (imunitn\u00ed bu\u0148ky v mozku) k odstran\u011bn\u00ed \u0161kodliv\u00fdch protein\u016f.<\/span><\/p>\n

\n
\n
\n

2. Parkinsonova nemoc<\/span><\/h2>\n<\/div>\n<\/div>\n<\/div>\n

P\u0159i Parkinsonov\u011b chorob\u011b vede postupn\u00e1 ztr\u00e1ta neuron\u016f produkuj\u00edc\u00edch dopamin k motorick\u00fdm projev\u016fm, jako jsou t\u0159es a ztuhlost.<\/span><\/p>\n

Ruta a jej\u00ed slo\u017eka rutin zde prok\u00e1zaly slibn\u00e9 \u00fa\u010dinky v preklinick\u00fdch studi\u00edch, proto\u017ee inhibuj\u00ed \u0161kodliv\u00e9 enzymy. Jedn\u00edm z hlavn\u00edch p\u0159isp\u011bvatel\u016f k\u00a0<\/span>Parkinsonov\u011b chorob\u011b<\/span><\/a>\u00a0je monoaminooxid\u00e1za B (MAO-B) \u2013 enzym, kter\u00fd rozkl\u00e1d\u00e1 dopamin.<\/span><\/p>\n

Schopnost ruty inhibovat MAO-B pom\u00e1h\u00e1 zachovat hladiny dopaminu s podobn\u00fdm \u00fa\u010dinkem jako m\u00e1 p\u0159i l\u00e9\u010db\u011b Parkinsonovy choroby l\u00e9k selegilin.<\/span><\/p>\n

T\u00edm v\u0161ak p\u0159\u00ednosy ruty nekon\u010d\u00ed. Rutin tak\u00e9 sni\u017euje oxida\u010dn\u00ed stres a zabra\u0148uje tvorb\u011b \u0161kodliv\u00fdch vedlej\u0161\u00edch metabolick\u00fdch produkt\u016f, kter\u00e9 po\u0161kozuj\u00ed neurony.<\/span><\/p>\n

Ruta d\u00e1le p\u0159\u00edmo chr\u00e1n\u00ed dopaminergn\u00ed neurony. Ve studi\u00edch na zv\u00ed\u0159atech or\u00e1ln\u00ed pod\u00e1v\u00e1n\u00ed rutinu chr\u00e1nilo mozkov\u00e9 bu\u0148ky p\u0159ed toxiny, kter\u00e9 napodobuj\u00ed symptomy Parkinsonovy choroby. Pozoruhodn\u00e9 je, \u017ee l\u00e9\u010den\u00e1 zv\u00ed\u0159ata vykazovala zlep\u0161en\u00fd pohyb, koordinaci a zdrav\u00ed mozku, co\u017e nazna\u010duje, \u017ee rutin m\u016f\u017ee zpomalovat progresi onemocn\u011bn\u00ed.<\/span><\/p>\n

No a kone\u010dn\u011b rutin zvy\u0161uje plasticitu nerv\u016f. V\u00fdta\u017eky z ruty podporuj\u00ed r\u016fst neurit\u016f. Jedn\u00e1 se o proces, kter\u00fd je rozhoduj\u00edc\u00ed pro opravu a vytv\u00e1\u0159en\u00ed spojen\u00ed mezi neurony. To nazna\u010duje roli rutinu p\u0159i zvy\u0161ov\u00e1n\u00ed adaptability a odolnosti mozku.<\/span><\/p>\n

3. Huntingtonova nemoc<\/span><\/h2>\n

Huntingtonova choroba je genetick\u00e1 porucha, kter\u00e1 zp\u016fsobuje pohybov\u00e9 probl\u00e9my a kognitivn\u00ed pokles. V\u00fdzkum vlivu ruty u Huntingtonovy chroby, i kdy\u017e je m\u00e9n\u011b rozs\u00e1hl\u00fd, p\u0159inesl zaj\u00edmav\u00e9 informace.<\/span><\/p>\n

V\u011bdci zjistili, \u017ee p\u016fsob\u00ed proti toxin\u016fm. Na zv\u00ed\u0159ec\u00edch modelech rutin chr\u00e1nil neurony p\u0159ed toxick\u00fdmi l\u00e1tkami, kter\u00e9 napodobuj\u00ed symptomy Huntingtonovy choroby, zlep\u0161oval p\u0159e\u017eit\u00ed bun\u011bk a sni\u017eoval jejich po\u0161kozen\u00ed.<\/span><\/p>\n

Rutin d\u00e1le podporuje bun\u011b\u010dn\u00e9 zdrav\u00ed. Studie vyu\u017e\u00edvaj\u00edc\u00ed modelov\u00fd organismus\u00a0<\/span>C. elegans<\/span><\/em>\u00a0zjistila, \u017ee rutin odd\u00e1lil st\u00e1rnut\u00ed, sn\u00ed\u017eil smrt neuronov\u00fdch bun\u011bk a aktivoval dr\u00e1hy zapojen\u00e9 do bun\u011b\u010dn\u00e9 opravy. Tato zji\u0161t\u011bn\u00ed poukazuj\u00ed na potenci\u00e1l rutinu p\u0159i podpo\u0159e zdrav\u00ed mozku.<\/span><\/p>\n

4. Nervov\u00e1 plasticita a p\u0159e\u017eit\u00ed bun\u011bk<\/span><\/h2>\n

Jedn\u00edm z nejzaj\u00edmav\u011bj\u0161\u00edch aspekt\u016f ruty je jej\u00ed schopnost ovliv\u0148ovat sign\u00e1ln\u00ed dr\u00e1hy, kter\u00e9 \u0159\u00edd\u00ed nervovou plasticitu, \u010dili schopnost mozku p\u0159izp\u016fsobit se a vytv\u00e1\u0159et nov\u00e1 spojen\u00ed.<\/span><\/p>\n

Uk\u00e1zalo se, \u017ee extrakty z ruty aktivuj\u00ed tyto sign\u00e1ln\u00ed dr\u00e1hy. Stimulac\u00ed sign\u00e1ln\u00edch molekul, jako jsou Akt a ERK, ruta podporuje p\u0159e\u017eit\u00ed a diferenciaci bun\u011bk.<\/span><\/p>\n

Nakonec se tak\u00e9 uk\u00e1zalo, \u017ee ruta podporuje diferenciaci nervov\u00fdch bun\u011bk. V\u00fdta\u017eek z n\u00ed povzbuzuje nediferencovan\u00e9 nervov\u00e9 bu\u0148ky, aby se vyvinuly na specializovan\u00e9 neurony \u2013 co\u017e je kritick\u00fd krok p\u0159i oprav\u011b mozku.<\/span><\/p>\n

Jak v\u00fdzkumn\u00edci odhaluj\u00ed st\u00e1le v\u00edce informac\u00ed o \u00faloze ruty p\u0159i podpo\u0159e nervov\u00e9ho zdrav\u00ed, jednoho dne se ruta m\u016f\u017ee st\u00e1t cenn\u00fdm spojencem v boji proti chorob\u00e1m mozku.<\/span><\/p>\n

Autor: Olivia Cook, Zdroj:\u00a0<\/span>naturalnews.com<\/span><\/a><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

P\u0159i hled\u00e1n\u00ed \u0159e\u0161en\u00ed neurodegenerativn\u00edch chorob, jako jsou Alzheimerova, Huntingtonova nebo Parkinsonova choroba, v\u011bdci zkoumaj\u00ed p\u0159\u00edrodn\u00ed…<\/p>\n","protected":false},"author":2,"featured_media":69163,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[7119,1155,2382,21],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/69162"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=69162"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/69162\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/69163"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=69162"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=69162"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=69162"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}