{"id":66784,"date":"2024-11-24T00:35:34","date_gmt":"2024-11-23T23:35:34","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=66784"},"modified":"2024-11-23T16:24:49","modified_gmt":"2024-11-23T15:24:49","slug":"cina-vyvinula-chirurgicky-postup-k-lecbe-alzheimerovy-choroby","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2024\/11\/24\/cina-vyvinula-chirurgicky-postup-k-lecbe-alzheimerovy-choroby\/","title":{"rendered":"\u010c\u00edna vyvinula chirurgick\u00fd postup k l\u00e9\u010db\u011b Alzheimerovy choroby"},"content":{"rendered":"
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\u010c\u00edna \u00fasp\u011b\u0161n\u011b vynalezla chirurgii k l\u00e9\u010db\u011b Alzheimerovy choroby. Procedura zn\u00e1m\u00e1 jako\u00a0hlubok\u00e1 cervik\u00e1ln\u00ed lymfaticko-ven\u00f3zn\u00ed anastom\u00f3za (LVA)<\/strong>\u00a0se zam\u011b\u0159uje na lymfatick\u00fd syst\u00e9m na krku. K dne\u0161n\u00edmu dni bylo provedeno 42 klinick\u00fdch studi\u00ed a v\u0161echny byly hl\u00e1\u0161eny jako \u00fasp\u011b\u0161n\u00e9.<\/p>\n

V jednom p\u0159\u00edpad\u011b byla operace LVA provedena u 76let\u00e9ho mu\u017ee se st\u0159edn\u011b t\u011b\u017ekou Alzheimerovou chorobou. V\u00fdsledky uk\u00e1zaly v\u00fdrazn\u00e9 zlep\u0161en\u00ed jeho symptom\u016f: dva m\u011bs\u00edce po operaci se mu nejen v\u00fdrazn\u011b obnovila pam\u011b\u0165, ale byl tak\u00e9 schopen norm\u00e1ln\u011b komunikovat s ostatn\u00edmi.<\/p>\n

Teoretick\u00fd z\u00e1klad operace LVA<\/strong><\/span>
\nZ\u00e1kladem v\u00fdkonu je p\u0159edpoklad, \u017ee Alzheimerova choroba je zp\u016fsobena abnorm\u00e1ln\u00ed akumulac\u00ed A\u03b2 amyloidn\u00edch protein\u016f a abnorm\u00e1ln\u00ed fosforylac\u00ed tau protein\u016f v mozku. Oba jsou hlavn\u00edmi faktory rozvoje onemocn\u011bn\u00ed.<\/p>\n

Operace vyu\u017e\u00edv\u00e1 supermikrochirurgick\u00e9 techniky k p\u0159esm\u011brov\u00e1n\u00ed lymfatick\u00e9ho ob\u011bhu v mozkov\u00fdch plen a urychlen\u00ed n\u00e1vratu intracerebr\u00e1ln\u00ed lymfy p\u0159es jugul\u00e1rn\u00ed foramen na spodin\u011b lebn\u00ed. To odstran\u00ed v\u00edce metabolick\u00e9ho odpadu z mozku, potenci\u00e1ln\u011b zvr\u00e1tit degenerativn\u00ed l\u00e9ze v mozku a zpomalit progresi onemocn\u011bn\u00ed.<\/p>\n

Jak funguje operace LVA<\/strong><\/span>
\nPostup lze ch\u00e1pat jako proces mechanick\u00e9ho \u010di\u0161t\u011bn\u00ed. Abnorm\u00e1ln\u00ed hromad\u011bn\u00ed amyloidn\u00edch protein\u016f v mozc\u00edch star\u0161\u00edch lid\u00ed p\u0159ipom\u00edn\u00e1 ucpan\u00fd kanaliza\u010dn\u00ed syst\u00e9m, z n\u011bho\u017e nelze \u201eodpad\u201c odstranit v\u010das. Hlubok\u00e1 kr\u010dn\u00ed lymfaticko-ven\u00f3zn\u00ed anastom\u00f3za v\u00fdrazn\u011b urychluje toto odstra\u0148ov\u00e1n\u00ed a zlep\u0161uje \u00fa\u010dinnost odstra\u0148ov\u00e1n\u00ed \u201eodpadu\u201c.<\/p>\n

11. listopadu profesor Tang Juyu, \u0159editel Mikrochirurgick\u00e9ho rekonstruk\u010dn\u00edho centra v nemocnici Xiangya Central South University, provedl 42. operaci LVA. Vzhledem k minim\u00e1ln\u011b invazivn\u00ed povaze z\u00e1kroku mohou b\u00fdt pacienti vzh\u016fru a pohybovat se ji\u017e druh\u00fd den.<\/p>\n

V\u00fdsledky a v\u00fdhled<\/strong><\/span>
\nMezi 42 pacienty mnoz\u00ed vyk\u00e1zali nejen obnovu pam\u011bti, ale tak\u00e9 v\u00fdznamnou zm\u011bnu v jejich chov\u00e1n\u00ed. Pacienti, kte\u0159\u00ed byli d\u0159\u00edve lhostejn\u00ed a ml\u010denliv\u00ed, se p\u0159i kontroln\u00edch vy\u0161et\u0159en\u00edch jevili vesel\u00ed a upov\u00eddan\u00ed.<\/p>\n

P\u0159esto\u017ee u mnoha pacient\u016f doch\u00e1z\u00ed po operaci k v\u00fdrazn\u00e9mu zlep\u0161en\u00ed symptom\u016f, odborn\u00edci zd\u016fraz\u0148uj\u00ed, \u017ee tento postup v sou\u010dasnosti nab\u00edz\u00ed nov\u00fd pohled na l\u00e9\u010dbu Alzheimerovy choroby. Jeho konkr\u00e9tn\u00ed \u00fa\u010dinnost v\u0161ak mus\u00ed je\u0161t\u011b potvrdit dal\u0161\u00ed v\u00fdzkum.<\/p>\n<\/div>\n<\/div>\n

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Zdroj<\/a><\/span><\/h3>\n

 <\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u010c\u00edna \u00fasp\u011b\u0161n\u011b vynalezla chirurgii k l\u00e9\u010db\u011b Alzheimerovy choroby. Procedura zn\u00e1m\u00e1 jako\u00a0hlubok\u00e1 cervik\u00e1ln\u00ed lymfaticko-ven\u00f3zn\u00ed anastom\u00f3za (LVA)\u00a0se…<\/p>\n","protected":false},"author":2,"featured_media":66785,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[2958,30,629,3952],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/66784"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=66784"}],"version-history":[{"count":1,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/66784\/revisions"}],"predecessor-version":[{"id":66786,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/66784\/revisions\/66786"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/66785"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=66784"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=66784"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=66784"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}