{"id":62764,"date":"2024-09-24T02:10:35","date_gmt":"2024-09-24T00:10:35","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=62764"},"modified":"2024-09-24T02:10:35","modified_gmt":"2024-09-24T00:10:35","slug":"who-schvalila-vakcinu-proti-opicim-nestovicim-pro-africke-deti-navzdory-chybejicim-klinickym-zkouskam","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2024\/09\/24\/who-schvalila-vakcinu-proti-opicim-nestovicim-pro-africke-deti-navzdory-chybejicim-klinickym-zkouskam\/","title":{"rendered":"WHO schv\u00e1lila vakc\u00ednu proti opi\u010d\u00edm ne\u0161tovic\u00edm pro africk\u00e9 d\u011bti \u2013 navzdory chyb\u011bj\u00edc\u00edm klinick\u00fdm zkou\u0161k\u00e1m!"},"content":{"rendered":"
<\/div>\n

Sv\u011btov\u00e1 zdravotnick\u00e1 organizace (WHO) ned\u00e1vno schv\u00e1lila prvn\u00ed vakc\u00ednu proti mpox (opi\u010d\u00edm ne\u0161tovic\u00edm) pro dosp\u011bl\u00e9 v Africe. Jedn\u00e1 se o modifikovanou vakc\u00ednu Vaccinia Ankara-Bavarian Nordic (MVA-BN) od d\u00e1nsk\u00e9 farmaceutick\u00e9 spole\u010dnosti Bavarian Nordic.<\/strong><\/p>\n

Podle WHO schv\u00e1len\u00ed urychl\u00ed p\u0159\u00edstup k vakc\u00edn\u011b pro miliony lid\u00ed, aby se omezil p\u0159enos onemocn\u011bn\u00ed a pomohlo se zabr\u00e1nit masov\u00e9mu propuknut\u00ed nemoci.<\/span><\/p>\n

\u201eToto prvn\u00ed p\u0159edb\u011b\u017en\u00e9 schv\u00e1len\u00ed vakc\u00edny proti mpox je d\u016fle\u017eit\u00fdm krokem v na\u0161em boji proti t\u00e9to nemoci, a to jak v kontextu sou\u010dasn\u00e9ho propuknut\u00ed nemoci v Africe, tak iv budoucnosti,\u201c<\/span><\/em>\u00a0\u0159ekl gener\u00e1ln\u00ed \u0159editel WHO Dr. Tedros Adhanem Ghebreyesus.<\/span><\/p>\n

\u201eNyn\u00ed pot\u0159ebujeme urychlit zad\u00e1v\u00e1n\u00ed zak\u00e1zek, z\u00edsk\u00e1v\u00e1n\u00ed dotac\u00ed a distribuci, abychom zajistili spravedliv\u00fd p\u0159\u00edstup k vakc\u00edn\u00e1m tam, kde jsou nejv\u00edce zapot\u0159eb\u00ed, spolu s dal\u0161\u00edmi n\u00e1stroji ve\u0159ejn\u00e9ho zdrav\u00ed, abychom zabr\u00e1nili infekc\u00edm, zastavili p\u0159enos a zachr\u00e1nili \u017eivoty.\u201c<\/span><\/em><\/p>\n

Vakc\u00edny mohou b\u00fdt pod\u00e1v\u00e1ny lidem star\u0161\u00edm 18 let v re\u017eimu dvoud\u00e1vkov\u00e9 injekce podan\u00e9 s odstupem \u010dty\u0159 t\u00fddn\u016f.<\/span><\/p>\n

Po p\u0159edchoz\u00edm uskladn\u011bn\u00ed v chladu se vakc\u00edna m\u016f\u017ee uchov\u00e1vat v chladni\u010dce a\u017e osm t\u00fddn\u016f v lahvi\u010dk\u00e1ch p\u0159i teplot\u011b alespo\u0148 7,8 \u00b0C nebo chladn\u011bj\u0161\u00ed. WHO v\u0161ak dodalo, \u017ee vakc\u00ednu lze pou\u017e\u00edt i pro kojence, d\u011bti, dosp\u00edvaj\u00edc\u00ed a t\u011bhotn\u00e9 \u017eeny.<\/span><\/p>\n

\u201eZat\u00edmco vakc\u00edna MVA-BN v sou\u010dasnosti nen\u00ed licencov\u00e1na pro osoby mlad\u0161\u00ed 18 let, tato vakc\u00edna se m\u016f\u017ee pou\u017e\u00edt \u201eoff-label\u201c (mimo protokol) iu kojenc\u016f, d\u011bt\u00ed, dosp\u00edvaj\u00edc\u00edch, t\u011bhotn\u00fdch \u017een a imunokompromitovan\u00fdch lid\u00ed.<\/span><\/em><\/p>\n

To znamen\u00e1, \u017ee pou\u017eit\u00ed vakc\u00edny se doporu\u010duje v prost\u0159ed\u00ed propuknut\u00ed nemoci, kde v\u00fdhody o\u010dkov\u00e1n\u00ed p\u0159evy\u0161uj\u00ed potenci\u00e1ln\u00ed rizika,\u201c<\/span><\/em>\u00a0uv\u00e1d\u00ed webov\u00e1 str\u00e1nka WHO.<\/span><\/p>\n

Strategick\u00e1 poradn\u00ed skupina odborn\u00edk\u016f na imunizaci WHO nav\u00edc prozkoumala v\u0161echny dostupn\u00e9 d\u016fkazy a doporu\u010dila pou\u017eit\u00ed uveden\u00e9 vakc\u00edny. Jej\u00ed zpr\u00e1va s n\u00e1zvem\u00a0<\/span>Weekly Epidemiological Record<\/span><\/em>\u00a0(T\u00fddenn\u00ed imunologick\u00fd z\u00e1znam) uvedla, \u017ee \u201evakc\u00edna MVA-BN nebyla specificky zkoum\u00e1na v klinick\u00fdch studi\u00edch u d\u011bt\u00ed.\u201c<\/span><\/p>\n

\u201eStejn\u00fd nereplikuj\u00edc\u00ed se virov\u00fd vektor MVA se pou\u017e\u00edv\u00e1 jako platforma pro dal\u0161\u00ed vakc\u00edny, kter\u00e9 zahrnuj\u00ed MVA-filo (Mvabea\u2122) proti onemocn\u011bn\u00ed vir\u016fm Ebola,\u201c<\/span><\/em>\u00a0uv\u00e1d\u00ed se ve zpr\u00e1v\u011b.<\/span><\/p>\n

\u201eVakc\u00edna proti Ebole je schv\u00e1lena v EU pro dosp\u011bl\u00e9 a d\u011bti ve v\u011bku 1 rok a star\u0161\u00ed. \u00dadaje z p\u011bti publikovan\u00fdch studi\u00ed o MVA-BN vakc\u00edn\u011b jako virov\u00e9 vektorov\u00e9 platform\u011b pro prevenci Eboly s celkovou populac\u00ed 52 229 d\u011bt\u00ed podporuj\u00ed p\u0159\u00edzniv\u00fd bezpe\u010dnostn\u00ed profil v\u00fdrobku\u201c.<\/span><\/em><\/p>\n

Auto\u0159i studie publikovan\u00e9 v odborn\u00e9m \u010dasopise BMJ prezentovali v\u00fdsledky o \u00fa\u010dinnosti vakc\u00edny MVA-BN u dosp\u011bl\u00fdch mu\u017e\u016f, ale ne\u0159\u00edkali nic o d\u011btech nebo t\u011bhotn\u00fdch \u017een\u00e1ch.<\/span><\/p>\n

Schv\u00e1len\u00ed zaveden\u00ed vakc\u00edny proti mpox rozzlobilo aktivisty, proto\u017ee zpochyb\u0148uj\u00ed jejich bezpe\u010dnost. Vedouc\u00ed v\u011bdeck\u00fd pracovn\u00edk odd\u011blen\u00ed ochrany zdrav\u00ed d\u011bt\u00ed Brian Hooker nazval jej\u00ed schv\u00e1len\u00ed pro kojence a d\u011bti v Africe \u201evlakov\u00fdm ne\u0161t\u011bst\u00edm v p\u0159\u00edprav\u011b\u201c.<\/span><\/p>\n

\u201eBezpe\u010dnostn\u00ed profil t\u00e9to vakc\u00edny u dosp\u011bl\u00fdch je ot\u0159esn\u00fd (a\u017e 2,1 procenta z\u00e1va\u017en\u00fdch srde\u010dn\u00edch p\u0159\u00edhod v klinick\u00fdch studi\u00edch) a vakc\u00edna nebyla dostate\u010dn\u011b testov\u00e1na na \u00fa\u010dinnost nebo bezpe\u010dnost v pediatrick\u00e9 populaci.<\/span><\/em><\/p>\n

Jin\u00fdmi slovy, WHO ani netu\u0161\u00ed, zda vakc\u00edna bude fungovat, respektive nev\u011bd\u00ed, jak\u00e9 \u0161kody zp\u016fsob\u00ed. WHO op\u011bt opustila z\u00e1sady dobr\u00e9ho ve\u0159ejn\u00e9ho zdrav\u00ed a m\u00e1vla kouzelnou o\u010dkovac\u00ed h\u016flkou nad vypuknut\u00edm mpoxu,\u201c<\/span><\/em>\u00a0\u0159ekl Hooker.<\/span><\/p>\n

L\u00e9ka\u0159 ve\u0159ejn\u00e9ho zdrav\u00ed a biotechnologick\u00fd konzultant Dr. David Bell tak\u00e9 zkritizoval WHO za p\u0159\u00edli\u0161n\u00e9 zam\u011b\u0159en\u00ed se na vakc\u00edny proti mpox a zanedb\u00e1v\u00e1n\u00ed \u0159e\u0161en\u00ed \u0161ir\u0161\u00edch probl\u00e9m\u016f ve\u0159ejn\u00e9ho zdrav\u00ed v Africe.<\/span><\/p>\n

(Souvisej\u00edc\u00ed: N\u011bmeck\u00fd l\u00e9ka\u0159\u00a0<\/span>\u0159\u00edk\u00e1<\/span><\/a>\u00a0, \u017ee opi\u010d\u00ed ne\u0161tovice jsou podvod \u2013 je to jen p\u00e1sov\u00fd opar vyvolan\u00fd \u201evakc\u00ednou\u201c proti covidu pojmenovan\u00fd jin\u00fdm n\u00e1zvem.)<\/span><\/p>\n

Vakc\u00edny proti mpox z USA a EU ji\u017e dorazily do Konga<\/span><\/h2>\n

P\u0159ibli\u017en\u011b 50 000 d\u00e1vek vakc\u00edny proti mpox ze Spojen\u00fdch st\u00e1t\u016f americk\u00fdch dorazilo do Kon\u017esk\u00e9 demokratick\u00e9 republiky dne 10. z\u00e1\u0159\u00ed 2024.<\/span><\/p>\n

Prvn\u00ed v\u00e1rka z Evropsk\u00e9 unie se dostala do hlavn\u00edho m\u011bsta Kinshasa, centra topeni\u0161t\u011b, p\u0159ed t\u00fddnem. T\u011bchto 100 000 d\u00e1vek vakc\u00edny Jynneos darovala EU prost\u0159ednictv\u00edm HERA, agentury EU pro nouzov\u00e9 zdravotn\u00ed situace. Dal\u0161\u00edch 100 000 d\u00e1vek bylo doru\u010deno posledn\u00ed v\u00edkend.<\/span><\/p>\n

50 000 d\u00e1vek z USA je tak\u00e9 vakc\u00edna Jynneos. Dal\u0161\u00ed v\u00e1rka pr\u00fd p\u0159ich\u00e1z\u00ed z Japonska.<\/span><\/p>\n

Cris Kacita Osako, koordin\u00e1tor n\u00e1rodn\u00edho v\u00fdboru pro reakci na opi\u010d\u00ed ne\u0161tovice, uvedl, \u017ee dosp\u011bl\u00ed v Equateur, Ji\u017en\u00edm Kivu a Sankuru budou o\u010dkov\u00e1ni nejd\u0159\u00edve od 2. \u0159\u00edjna 2024.<\/span><\/p>\n

Od za\u010d\u00e1tku roku 2024 bylo na cel\u00e9m africk\u00e9m kontinentu potvrzeno 5 549 p\u0159\u00edpad\u016f mpox s 643 souvisej\u00edc\u00edmi \u00famrt\u00edmi. P\u0159\u00edpady v Kon\u017esk\u00e9 demokratick\u00e9 republice (KDR) tvo\u0159ily 91 procent v\u0161ech p\u0159\u00edpad\u016f.<\/span><\/p>\n

V\u011bt\u0161ina infekc\u00ed mpox v KDR a Burundi, druh\u00e9 nejv\u00edce posti\u017een\u00e9 zemi, je u d\u011bt\u00ed mlad\u0161\u00edch 15 let.<\/span><\/p>\n

KDR vydala nouzov\u00e9 schv\u00e1len\u00ed vakc\u00edny, kter\u00e1 ji\u017e byla pou\u017eita v Evrop\u011b a Spojen\u00fdch st\u00e1tech u dosp\u011bl\u00fdch. V sou\u010dasnosti bude spu\u0161t\u011bn\u00ed o\u010dkov\u00e1n\u00ed vyhrazeno pro dosp\u011bl\u00e9, p\u0159i\u010dem\u017e prioritn\u00edmi skupinami budou ti, kte\u0159\u00ed byli v \u00fazk\u00e9m kontaktu s infikovan\u00fdmi lidmi a sexu\u00e1ln\u00edmi partnery, \u0159ekl gener\u00e1ln\u00ed \u0159editel CDC pro Afriku Dr. Jean Kaseya.<\/span><\/p>\n

Evropsk\u00e1 agentura pro l\u00e9ky (EMA) v\u0161ak zkoum\u00e1 dal\u0161\u00ed \u00fadaje, aby ji mohla pod\u00e1vat i d\u011btem ve v\u011bku od 12 do 17 let, co\u017e by se mohlo st\u00e1t koncem m\u011bs\u00edce, uvedl gener\u00e1ln\u00ed \u0159editel HERA Laurent Muschel.<\/span><\/p>\n

Z\u00e1v\u011br<\/span><\/h2>\n

Na str\u00e1nce\u00a0<\/span>Vaccines.news<\/span><\/a>\u00a0naleznete dal\u0161\u00ed \u010dl\u00e1nky souvisej\u00edc\u00ed s t\u00e9matem opi\u010d\u00edch ne\u0161tovic.<\/span><\/p>\n

Tak\u00e9 si prohl\u00e9dn\u011bte\u00a0<\/span>video<\/span><\/a>\u00a0n\u00ed\u017ee, kter\u00e9 hovo\u0159\u00ed o zaveden\u00ed vakc\u00edn proti mpox v Africe u dosp\u011bl\u00fdch a d\u011bt\u00ed navzdory tomu, \u017ee nebyly provedeny klinick\u00e9 zkou\u0161ky:<\/span><\/p>\n