{"id":6262,"date":"2021-11-18T10:31:48","date_gmt":"2021-11-18T09:31:48","guid":{"rendered":"http:\/\/www.infokuryr.cz\/n\/?p=6262"},"modified":"2021-11-18T10:31:48","modified_gmt":"2021-11-18T09:31:48","slug":"svedska-studie-spike-protein-ktery-koduje-geneticky-material-ve-vakcinach-proti-covidu-muze-znicit-adaptovanou-imunitu-ktera-nas-chrani","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2021\/11\/18\/svedska-studie-spike-protein-ktery-koduje-geneticky-material-ve-vakcinach-proti-covidu-muze-znicit-adaptovanou-imunitu-ktera-nas-chrani\/","title":{"rendered":"\u0160v\u00e9dsk\u00e1 studie: Spike protein, kter\u00fd k\u00f3duje genetick\u00fd materi\u00e1l ve \u201evakc\u00edn\u00e1ch\u201c proti Covidu, m\u016f\u017ee zni\u010dit adaptovanou imunitu, kter\u00e1 n\u00e1s chr\u00e1n\u00ed"},"content":{"rendered":"
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V\u011bdci z Katedry molekul\u00e1rn\u00edch biologick\u00fdch v\u011bd Stockholmsk\u00e9 univerzity (\u0160v\u00e9dsko) a Katedry klinick\u00e9 mikrobiologie na Univerzit\u011b Ume\u00e5 (tak\u00e9 \u0160v\u00e9dsko) provedli\u00a0<\/span>studii<\/span><\/a><\/strong> , kter\u00e1 prok\u00e1zala, \u017ee spike protein [nach\u00e1zej\u00edc\u00ed se v \u201evakc\u00edn\u00e1ch\u201c proti CoVID] je opravou po\u0161kozen\u00ed DNA a mechanismy adaptivn\u00ed imunity infiltrovan\u00e9 in vitro a \u017ee \u201e <\/span>spike proteiny SARS-CoV-2 mohou oslabit syst\u00e9m opravy DNA star\u0161\u00edch lid\u00ed a n\u00e1sledn\u011b naru\u0161it adaptivn\u00ed imunitu<\/span><\/em>\u00a0\u201c.<\/span><\/p>\n

Podle v\u011bdc\u016f \u201ena\u0161e v\u00fdsledky tak\u00e9 nazna\u010duj\u00ed mo\u017en\u00fd vedlej\u0161\u00ed \u00fa\u010dinek cel\u00e9 vakc\u00edny zalo\u017een\u00e9 na spike\u201c, kter\u00e1 krom\u011b vedlej\u0161\u00edch \u00fa\u010dink\u016f ni\u010d\u00ed na\u0161i p\u0159irozenou imunitu.<\/span><\/p>\n

Abstrakt studie \u0159\u00edk\u00e1:<\/span><\/p>\n

\u201eZde uv\u00e1d\u00edme pomoc\u00ed in vitro bun\u011b\u010dn\u00e9 linie, \u017ee spike protein SARS-CoV-2 v\u00fdznamn\u011b inhibuje opravu po\u0161kozen\u00ed DNA, co\u017e je nezbytn\u00e9 pro \u00fa\u010dinnou V(D)J rekombinaci v adaptivn\u00ed imunit\u011b.\u00a0Mechanicky jsme zjistili, \u017ee spike protein je lokalizov\u00e1n v bun\u011b\u010dn\u00e9m j\u00e1dru a inhibuje opravu po\u0161kozen\u00ed DNA t\u00edm, \u017ee br\u00e1n\u00ed n\u00e1boru nejd\u016fle\u017eit\u011bj\u0161\u00edch protein\u016f opravy DNA BRCA1 a 53BP1 v m\u00edst\u011b po\u0161kozen\u00ed.\u00a0Na\u0161e v\u00fdsledky nazna\u010duj\u00ed potenci\u00e1ln\u00ed molekul\u00e1rn\u00ed mechanismus, kter\u00fdm by spike protein mohl interferovat s adaptivn\u00ed imunitou a zd\u016fraz\u0148ovat potenci\u00e1ln\u00ed vedlej\u0161\u00ed \u00fa\u010dinky dlouhodob\u011b p\u016fsob\u00edc\u00edch spike vakc\u00edn na b\u00e1zi protein\u016f.<\/em><\/p>\n<\/div>\n<\/div>\n

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ZDROJ: ESTUDIO SUECO: LA PROTE\u00cdN SPIKE QUE CODIFICA EL MATERIAL GEN\u00c9TICO DE LAS ‚VACUNAS‘ COVID PUEDE DESTRUIR LA INMUNIDAD ADAPTATIVA QUE NOS PROTEGE<\/a><\/span><\/h3>\n

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V\u011bdci z Katedry molekul\u00e1rn\u00edch biologick\u00fdch v\u011bd Stockholmsk\u00e9 univerzity (\u0160v\u00e9dsko) a Katedry klinick\u00e9 mikrobiologie na Univerzit\u011b…<\/p>\n","protected":false},"author":2,"featured_media":5969,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[454,839,651],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/6262"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=6262"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/6262\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/5969"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=6262"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=6262"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=6262"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}