{"id":59336,"date":"2024-08-05T06:23:48","date_gmt":"2024-08-05T04:23:48","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=59336"},"modified":"2024-08-05T06:23:48","modified_gmt":"2024-08-05T04:23:48","slug":"co-se-stane-kdyz-do-sebe-vstriknete-leky-na-hubnuti-obsahujici-peptidy-z-plazu","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2024\/08\/05\/co-se-stane-kdyz-do-sebe-vstriknete-leky-na-hubnuti-obsahujici-peptidy-z-plazu\/","title":{"rendered":"Co se stane, kdy\u017e do sebe vst\u0159\u00edknete l\u00e9ky na hubnut\u00ed obsahuj\u00edc\u00ed peptidy z plaz\u016f"},"content":{"rendered":"
<\/div>\n

L\u00e9ky na hubnut\u00ed, jako jsou Ozempic, Wegovy \u010di Rybelsus (a jin\u00e9 s \u00fa\u010dinnou l\u00e1tkou semaglutid), za\u010dali popularizovat mnoz\u00ed alopati\u010dt\u00ed l\u00e9ka\u0159i, kte\u0159\u00ed sv\u00fdm pacient\u016fm siln\u011b protla\u010duj\u00ed farmaceutick\u00e9 l\u00e9ky.<\/strong><\/p>\n

Nov\u00e9 d\u016fkazy v\u0161ak nazna\u010duj\u00ed, \u017ee tyto nov\u00e9 l\u00e9ky p\u0159edstavuj\u00ed v\u00e1\u017en\u00e1 zdravotn\u00ed rizika, kter\u00e1 mohou \u010dlov\u011bku zni\u010dit \u017eivot.<\/span><\/p>\n

Podle nov\u00e9 studie jsou u\u017eivatel\u00e9 l\u00e9k\u016f obsahuj\u00edc\u00edch semaglutid vystaveni zv\u00fd\u0161en\u00e9mu riziku vzniku stavu, kter\u00fd potenci\u00e1ln\u011b m\u016f\u017ee v\u00e9st k oslepnut\u00ed. To se toti\u017e m\u016f\u017ee st\u00e1t, kdy\u017e si do t\u011bla vst\u0159\u00edknete peptidy plaz\u00edho jedu.<\/span><\/p>\n

Jedovat\u00fd Ozempic a Wegovy zvy\u0161uj\u00ed riziko slepoty<\/span><\/h2>\n

Studie<\/span><\/a>\u00a0publikovan\u00e1 v medic\u00ednsk\u00e9m \u017eurn\u00e1lu JAMA Ophthalmology vyvolala obavy z l\u00e1tky semaglutid, l\u00e9kem pou\u017e\u00edvan\u00fdm k l\u00e9\u010db\u011b diabetu 2. typu a obezity, a jej\u00edm mo\u017en\u00fdm souvisem se zv\u00fd\u0161en\u00fdm rizikem nearteritick\u00e9 p\u0159edn\u00ed ischemick\u00e9 neuropatie zrakov\u00e9ho nervu (NAION).<\/span><\/p>\n

Tento z\u00e1va\u017en\u00fd stav m\u016f\u017ee v\u00e9st k n\u00e1hl\u00e9 ztr\u00e1t\u011b zraku a je charakterizov\u00e1n po\u0161kozen\u00edm zrakov\u00e9ho nervu.<\/span><\/p>\n

Studie, kterou vedla Jimena Tatiana Hathawayov\u00e1, MD, MPH, zkoumala souvislost mezi u\u017e\u00edv\u00e1n\u00edm semaglutidu a v\u00fdskytem onemocn\u011bn\u00ed NAION.<\/span><\/p>\n

V\u00fdzkumn\u00edci provedli retrospektivn\u00ed p\u00e1rovac\u00ed kohortovou studii s pou\u017eit\u00edm \u00fadaj\u016f z centralizovan\u00e9ho registru zahrnuj\u00edc\u00edho pacienty, kte\u0159\u00ed byli hodnoceni neurooftalmology na akademick\u00e9 instituci v obdob\u00ed od prosince 2017 do listopadu 2023.<\/span><\/p>\n

Studie zahrnovala 16 827 pacient\u016f, kte\u0159\u00ed nem\u011bli v p\u0159edchoz\u00ed anamn\u00e9ze onemocn\u011bn\u00ed NAION. Mezi nimi m\u011blo 710 pacient\u016f diabetes 2. typu (T2D) a 979 pacient\u016f m\u011blo nadv\u00e1hu nebo obezitu.<\/span><\/p>\n

V r\u00e1mci t\u011bchto skupin byly pacient\u016fm na zvl\u00e1dnut\u00ed jejich stav\u016f p\u0159edeps\u00e1ny bu\u010f l\u00e9ky se semaglutidem, nebo agonisty peptidov\u00e9ho receptoru nepodobn\u00e9ho glukagonu (GLP-1 RA).<\/span><\/p>\n

\u201eStudie zjistila, \u017ee lid\u00e9 s cukrovkou, kter\u00fdm je l\u00e9ka\u0159 p\u0159edepsal semaglutid a n\u00e1sledn\u011b jej u\u017e\u00edvali, m\u011bli v\u00edce ne\u017e \u010dty\u0159ikr\u00e1t vy\u0161\u0161\u00ed pravd\u011bpodobnost, \u017ee jim bude diagnostikov\u00e1no onemocn\u011bn\u00ed NAION,\u201c<\/span><\/em>\u00a0napsali auto\u0159i v tiskov\u00e9 zpr\u00e1v\u011b.<\/span><\/p>\n

Auto\u0159i d\u00e1le dodali:<\/span><\/p>\n

„Ti, kte\u0159\u00ed m\u011bli nadv\u00e1hu nebo byli ob\u00e9zn\u00ed a byl jim p\u0159edeps\u00e1n tento l\u00e9k, m\u011bli v\u00edce ne\u017e sedmkr\u00e1t vy\u0161\u0161\u00ed pravd\u011bpodobnost, \u017ee je postihne uveden\u00e1 diagn\u00f3za.“<\/span><\/em><\/p>\n

Ve skupin\u011b s diabetem typu 2 se vyskytlo 17 p\u0159\u00edpad\u016f NAION u pacient\u016f, kter\u00fdm byl p\u0159edeps\u00e1n semaglutid, v porovn\u00e1n\u00ed se \u0161esti pacienty, kter\u00fdm byla p\u0159edeps\u00e1na antidiabetika proti RA bez GLP-1.<\/span><\/p>\n

Kumulativn\u00ed incidence NAION b\u011bhem 36 m\u011bs\u00edc\u016f byla 8,9% v semaglutidov\u00e9 skupin\u011b oproti 1,8% v non-GLP-1 RA skupin\u011b.<\/span><\/p>\n

U ob\u00e9zn\u00edch pacient\u016f se ve skupin\u011b se semaglutidem vyskytlo 20 p\u0159\u00edpad\u016f NAION ve srovn\u00e1n\u00ed s 3 ve skupin\u011b s non-GLP-1 RA. Kumulativn\u00ed incidence NAION b\u011bhem 36 m\u011bs\u00edc\u016f byla 6,7% v semaglutidov\u00e9 skupin\u011b oproti 0,8% v non-GLP-1 RA skupin\u011b.<\/span><\/p>\n

Peptidy plaz\u00edho jedu zp\u016fsobuj\u00ed slepotu a dal\u0161\u00ed po\u0161kozen\u00ed org\u00e1n\u016f naru\u0161en\u00edm vagusu (bloudiv\u00e9ho nervu)<\/span><\/h2>\n

Ozempic a Wegovy obsahuj\u00ed syntetizovan\u00e9 peptidy p\u016fvodn\u011b vytvo\u0159en\u00e9 z jedu je\u0161t\u011brky kornatec mexick\u00fd (Heloderma suspectum). Jed t\u00e9to je\u0161t\u011brky obsahuje slou\u010deninu, kter\u00e1 dok\u00e1\u017ee regulovat hlad, podobn\u011b jako hormon p\u0159irozen\u011b produkovan\u00fd v lidsk\u00fdch st\u0159evech.<\/span><\/p>\n

Verze odvozen\u00e1 z je\u0161t\u011brky v\u0161ak vykazuje dlouhodob\u011bj\u0161\u00ed \u00fa\u010dinek, kter\u00fd se zam\u011b\u0159uje na bloudiv\u00fd nerv. Tento objev vydl\u00e1\u017edil cestu pro novou kategorii l\u00e9k\u016f zam\u011b\u0159en\u00fdch na obezitu a cukrovku, ale nutn\u011b naru\u0161uje org\u00e1nov\u00e9 syst\u00e9my.<\/span><\/p>\n

P\u0159\u00edpravek \u00fa\u010dinkuje tak, \u017ee naru\u0161uje sign\u00e1ly hladu p\u0159en\u00e1\u0161en\u00e9 z mozku do tr\u00e1vic\u00edho syst\u00e9mu. Tento jedovat\u00fd l\u00e9k dosahuje \u00fabytek hmotnosti p\u0159edev\u0161\u00edm naru\u0161en\u00edm funkce bloudiv\u00e9ho nervu.<\/span><\/p>\n

Jako nejdel\u0161\u00ed a nejd\u016fle\u017eit\u011bj\u0161\u00ed nerv v lidsk\u00e9m t\u011ble\u00a0<\/span>bloudiv\u00fd nerv<\/span><\/a>\u00a0vych\u00e1z\u00ed z mozku a propojuje jej s mnoha \u017eivotn\u011b d\u016fle\u017eit\u00fdmi org\u00e1ny, koordinuje podn\u011bty pro tr\u00e1ven\u00ed, krevn\u00ed ob\u011bh, d\u00fdch\u00e1n\u00ed, kognitivn\u00ed funkce a dal\u0161\u00ed t\u011blesn\u00e9 \u010dinnosti.<\/span><\/p>\n

Vzhledem k rozs\u00e1hl\u00e9mu vlivu l\u00e9ku na bloud\u00ed nerv je potenci\u00e1l po\u0161kozen\u00ed org\u00e1n\u016f v cel\u00e9m t\u011ble zna\u010dn\u011b vysok\u00fd.<\/span><\/p>\n

V\u00fdzkumn\u00edci teprve nyn\u00ed zji\u0161\u0165uj\u00ed mo\u017en\u00e9 negativn\u00ed \u00fa\u010dinky na o\u010di. Nebude v\u0161ak z\u0159ejm\u011b dlouho trvat, ne\u017e zdokumentuj\u00ed dal\u0161\u00ed po\u0161kozen\u00ed nap\u0159\u00ed\u010d cel\u00fdmi org\u00e1nov\u00fdmi syst\u00e9my v t\u011ble, p\u0159ipom\u00ednaj\u00edc\u00ed syst\u00e9mov\u00e9 \u00fa\u010dinky pozorovan\u00e9 u ob\u011bt\u00ed kousnut\u00ed jedovat\u00fdm hadem.<\/span><\/p>\n

L\u00e9ky obsahuj\u00edc\u00ed semaglutid se nesm\u00ed u\u017e\u00edvat po del\u0161\u00ed dobu, proto\u017ee jed se hromad\u00ed v t\u011ble a postupn\u011b po\u0161kozuje bloudiv\u00fd nerv.<\/span><\/p>\n

Bloudiv\u00fd nerv reguluje tr\u00e1ven\u00ed, srde\u010dn\u00ed frekvenci, d\u00fdch\u00e1n\u00ed, \u0159e\u010d, polyk\u00e1n\u00ed a imunitn\u00ed funkce. V\u0161echny tyto syst\u00e9my budou nakonec negativn\u011b ovlivn\u011bny.<\/span><\/p>\n

Z\u00e1v\u011br<\/span><\/h2>\n

L\u00e9ky Ozempic a Wegovy dnes ji\u017e uv\u00e1d\u011bj\u00ed vedlej\u0161\u00ed \u00fa\u010dinky, kter\u00e9 koresponduj\u00ed se selh\u00e1n\u00edm t\u011bchto syst\u00e9m\u016f. Slepota je v\u0161ak jen za\u010d\u00e1tek z t\u011bch hor\u0161\u00edch n\u00e1sledk\u016f.<\/span><\/p>\n

Z\u00e1padn\u00ed zem\u011b \u010dek\u00e1 v p\u0159\u00ed\u0161t\u00edch letech exploze po\u0161kozen\u00ed org\u00e1n\u016f, proto\u017ee tyto l\u00e9ky jen v USA u\u017e\u00edv\u00e1 ji\u017e 15,5 milionu lid\u00ed.<\/span><\/p>\n

Autor: Lance D. Johnson, Zdroj:\u00a0<\/span>naturalnews.com<\/span><\/a><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

L\u00e9ky na hubnut\u00ed, jako jsou Ozempic, Wegovy \u010di Rybelsus (a jin\u00e9 s \u00fa\u010dinnou l\u00e1tkou semaglutid),…<\/p>\n","protected":false},"author":2,"featured_media":59337,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[6220,1020,21],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/59336"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=59336"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/59336\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/59337"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=59336"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=59336"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=59336"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}