{"id":54175,"date":"2024-05-21T00:36:37","date_gmt":"2024-05-20T22:36:37","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=54175"},"modified":"2024-05-20T10:28:29","modified_gmt":"2024-05-20T08:28:29","slug":"studie-ukazuje-ze-kontaminace-dna-ve-vakcine-covid-spolecnosti-pfizer-prekracuje-500krat-povolenou-uroven","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2024\/05\/21\/studie-ukazuje-ze-kontaminace-dna-ve-vakcine-covid-spolecnosti-pfizer-prekracuje-500krat-povolenou-uroven\/","title":{"rendered":"Studie ukazuje, \u017ee kontaminace DNA ve vakc\u00edn\u011b COVID spole\u010dnosti Pfizer p\u0159ekra\u010duje 500kr\u00e1t povolenou \u00farove\u0148"},"content":{"rendered":"
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Nov\u00e1 recenzovan\u00e1 studie vyvol\u00e1v\u00e1 obavy z neadekv\u00e1tn\u00edch testovac\u00edch metod k m\u011b\u0159en\u00ed kontaminant\u016f DNA v mRNA vakc\u00edn\u00e1ch COVID-19. Expert na genomiku Kevin McKernan kritizoval metody studie, ale tvrdil, \u017ee kontaminace je st\u00e1le nad povolen\u00fdmi limity a \u017ee sou\u010dasn\u00e9 p\u0159edpisy jsou „zcela nedostate\u010dn\u00e9.“<\/span><\/strong><\/em><\/p>\n

Nov\u00e1 recenzovan\u00e1 studie vyvol\u00e1v\u00e1 obavy ohledn\u011b metod pou\u017e\u00edvan\u00fdch k testov\u00e1n\u00ed mRNA vakc\u00edny Comirnaty COVID-19 vyroben\u00e9 spole\u010dnostmi Pfizer a BioNTech na mo\u017enou kontaminaci DNA.<\/span><\/p>\n

Ve studii zve\u0159ejn\u011bn\u00e9 tento m\u011bs\u00edc v Methods and Protocols n\u011bme\u010dt\u00ed v\u011bdci Brigitte K\u00f6nig a J\u00fcrgen O. Kirchner zpochyb\u0148uj\u00ed spolehlivost techniky kvantitativn\u00ed PCR (qPCR), kterou spole\u010dnost Pfizer-BioNTech pou\u017e\u00edv\u00e1 k m\u011b\u0159en\u00ed kontaminace DNA v \u00fa\u010dinn\u00e9 l\u00e1tce pou\u017eit\u00e9 ve vakc\u00edn\u011b. .<\/span><\/p>\n

V\u011bdci experimentovali s rozpou\u0161t\u011bn\u00edm Comirnatyho lipidov\u00fdch nano\u010d\u00e1stic. Na\u0161li ne\u010distoty DNA, kter\u00e9 byly 360 a\u017e 534kr\u00e1t vy\u0161\u0161\u00ed ne\u017e limit 10 ng (nanogram\u016f) na d\u00e1vku stanoven\u00fd regul\u00e1tory po cel\u00e9m sv\u011bt\u011b.<\/span><\/p>\n

V\u00fdzkumn\u00edci navrhli, \u017ee metody fluorescen\u010dn\u00ed spektroskopie by mohly spolehliv\u011bji kvantifikovat celkov\u00e9 mno\u017estv\u00ed kontaminace DNA v kone\u010dn\u00e9m vakc\u00ednov\u00e9m produktu p\u0159ipraven\u00e9m k pou\u017eit\u00ed.<\/span><\/p>\n

Kevin McKernan, hlavn\u00ed v\u011bdeck\u00fd pracovn\u00edk a zakladatel Medicinal Genomics, \u0159ekl The Defender, \u017ee a\u010dkoli auto\u0159i upozornili na n\u011bkter\u00e9 d\u016fle\u017eit\u00e9 body t\u00fdkaj\u00edc\u00ed se kontaminace DNA v mRNA vakc\u00edn\u00e1ch COVID-19, fluorometrick\u00e1 barviva mohou b\u00fdt nespolehliv\u00e1, co\u017e vede k nadm\u011brn\u00fdm nam\u011b\u0159en\u00fdm hodnot\u00e1m.<\/span><\/p>\n

„Masivn\u00ed nedostate\u010dn\u00e9 hl\u00e1\u0161en\u00ed kontaminace DNA“<\/span><\/strong><\/p>\n

V\u00fdrobci jako Pfizer-BioNTech pou\u017e\u00edvaj\u00ed testy kontaminace DNA zalo\u017een\u00e9 na metod\u011b qPCR aplikovan\u00e9 na \u00fa\u010dinnou l\u00e1tku vakc\u00edny p\u0159ed jej\u00edm zkombinov\u00e1n\u00edm s lipidov\u00fdmi nano\u010d\u00e1sticemi.<\/span><\/p>\n

K\u00f6nig a Kirchner pouk\u00e1zali na to, \u017ee test qPCR zkoum\u00e1 pouze mal\u00fd segment o 69 p\u00e1rech b\u00e1z\u00ed p\u016fvodn\u00edho templ\u00e1tu DNA o 7824 p\u00e1rech b\u00e1z\u00ed pou\u017eit\u00e9ho k v\u00fdrob\u011b vakc\u00edny mRNA.<\/span><\/p>\n

To znamen\u00e1, \u017ee spole\u010dnost Pfizer zkontroluje m\u00e9n\u011b ne\u017e 1 % p\u016fvodn\u00edho p\u0159\u00edsp\u011bvku. Zb\u00fdvaj\u00edc\u00edch 99 % z\u016fst\u00e1v\u00e1 neanalyzov\u00e1no, co\u017e vede k \u201emasivn\u00edmu podhodnocen\u00ed kontaminace DNA,\u201c uvedli v\u011bdci.<\/span><\/p>\n

V\u011bdci tak\u00e9 tvrdili, \u017ee tento mal\u00fd segment m\u016f\u017ee b\u00fdt zni\u010den b\u011bhem procesu enzymov\u00e9ho \u0161t\u011bpen\u00ed jinou rychlost\u00ed ne\u017e zb\u00fdvaj\u00edc\u00ed fragmenty templ\u00e1tu DNA, co\u017e d\u00e1le komplikuje p\u0159esn\u00e1 m\u011b\u0159en\u00ed.<\/span><\/p>\n

Dal\u0161\u00edm komplikuj\u00edc\u00edm faktorem je, \u017ee c\u00edlov\u00e1 sekvence qPCR se p\u0159ekr\u00fdv\u00e1 s \u00fasekem DNA naz\u00fdvan\u00fdm promotor T7, kter\u00fd se pou\u017e\u00edv\u00e1 k produkci mRNA. Bun\u011b\u010dn\u00e9 mechanismy nebo vedlej\u0161\u00ed produkty by se mohly v\u00e1zat na tuto promotorovou oblast a blokovat tak detekci testem qPCR.<\/span><\/p>\n

David Speicher, Ph.D., spoluautor s McKernanem a dal\u0161\u00edmi p\u0159edtiskov\u00e9 studie o fragmentech DNA ve vakc\u00edn\u00e1ch Moderna a Pfizer COVID-19, vyj\u00e1d\u0159il podobn\u00e9 obavy.<\/span><\/p>\n

PCR m\u016f\u017ee kvantifikovat pouze specifickou sekvenci DNA\/RNA, na kterou c\u00edl\u00ed pou\u017eit\u00e9 primery, vysv\u011btlil The Defender. Pokud se v t\u00e9to c\u00edlov\u00e9 sekvenci vyskytnou zlomy nebo mutace, DNA nebude replikov\u00e1na a z\u00e1t\u011b\u017e bude podhodnocena.\u201c<\/span><\/p>\n

„P\u0159edpokl\u00e1d\u00e1 se tak\u00e9, \u017ee DNA ve vakc\u00edn\u011b poch\u00e1z\u00ed pouze z plazmidu a ne z bakteri\u00e1ln\u00edho nebo jin\u00e9ho zdroje,“ \u0159ekl Speicher.<\/span><\/p>\n

McKernan pouk\u00e1zal na dal\u0161\u00ed probl\u00e9m: Regula\u010dn\u00ed org\u00e1ny umo\u017e\u0148uj\u00ed spole\u010dnosti Pfizer pou\u017e\u00edvat qPCR k m\u011b\u0159en\u00ed DNA a fluorometrii k m\u011b\u0159en\u00ed RNA.<\/span><\/p>\n

\u201eP\u0159edpisy EMA [Evropsk\u00e9 l\u00e9kov\u00e9 agentury] vy\u017eaduj\u00ed pom\u011brov\u00e9 m\u011b\u0159en\u00ed RNA:DNA,\u201c \u0159ekl. „Pom\u011bry by se nem\u011bly m\u011b\u0159it v centimetrech pro RNA a metrech pro DNA.“<\/span><\/p>\n

\u0158ekl, \u017ee Pfizer by m\u011bl m\u011b\u0159it RNA i DNA pomoc\u00ed fluorometrie nebo qPCR. „Kdy\u017e si dovol\u00ed kombinovat n\u00e1stroje, jako jsou tyto, umo\u017e\u0148uj\u00ed p\u0159\u00edm\u00fd podvod.“<\/span><\/p>\n

McKernan tak\u00e9 sd\u00edlel \u010d\u00e1st patentov\u00e9 p\u0159ihl\u00e1\u0161ky Moderny, kter\u00e1 uzn\u00e1v\u00e1, \u017ee qPCR je nevhodn\u00e1 pro m\u011b\u0159en\u00ed mal\u00fdch fragment\u016f DNA.<\/span><\/p>\n

„U\u017e nediskutujeme o tom, zda jsou nahr\u00e1vky kontaminovan\u00e9“<\/strong><\/span><\/p>\n

Aby se p\u0159ede\u0161lo n\u00e1strah\u00e1m qPCR, kter\u00e1 detekuje pouze malou \u010d\u00e1st kontaminovan\u00e9 DNA, K\u00f6nig a Kirchner navrhli pou\u017e\u00edt techniky fluorescen\u010dn\u00ed spektroskopie, jako je Qubit, ke kvantifikaci celkov\u00e9ho obsahu DNA v kone\u010dn\u00e9m vakc\u00ednov\u00e9m produktu.<\/span><\/p>\n

Tyto metody vyu\u017e\u00edvaj\u00ed fluorescen\u010dn\u00ed barviva, kter\u00e1 se specificky v\u00e1\u017eou na nukleov\u00e9 kyseliny, jako je DNA a RNA.<\/span><\/p>\n

V jejich experimentech fluorescen\u010dn\u00ed technikou s Comirnaty byla po rozbit\u00ed nano\u010d\u00e1stic zji\u0161t\u011bna kontaminace DNA, kter\u00e1 byla v\u00fdrazn\u011b nad limitem 10 ng\/d\u00e1vku.<\/span><\/p>\n

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Obr. 2. Kvantifikace celkov\u00e9 DNA v \u0161ar\u017e\u00edch Comirnaty pomoc\u00ed Qubit fluorometrie bez a s p\u0159id\u00e1n\u00edm Triton-X-100 jako detergentu pro dezintegraci lipidov\u00fdch nano\u010d\u00e1stic obsa\u017een\u00fdch ve formulaci vakc\u00edny. Zdroj: Brigitte K\u00f6nig a J\u00fcrgen O. Kirchner.<\/span><\/em><\/figcaption><\/figure>\n<\/div>\n

McKernan, kter\u00fd psal o omezen\u00edch fluorometrie na sv\u00e9m Substacku, nab\u00e1dal k opatrnosti p\u0159i zva\u017eov\u00e1n\u00ed v\u00fdsledk\u016f K\u00f6niga a Kirchnera.<\/span><\/p>\n

„Fluorometrick\u00e1 barviva mohou komunikovat mezi RNA a DNA, tak\u017ee velk\u00e9 mno\u017estv\u00ed RNA ve vakc\u00edn\u011b zp\u016fsobuje, \u017ee barvivo specifick\u00e9 pro DNA poskytuje ur\u010dit\u00fd sign\u00e1l z RNA,“ \u0159ekl The Defender. „To vede k nafouknut\u00fdm hodnot\u00e1m DNA ve studii K\u00f6nig.“<\/span><\/p>\n

Aby se tyto obavy vy\u0159e\u0161ily, McKernan \u0159ekl, \u017ee by v\u00fdzkumn\u00edci m\u011bli prov\u00e1d\u011bt kontrolu RN\u00e1zy. RN\u00e1za je enzym, kter\u00fd odstra\u0148uje RNA, tak\u017ee p\u0159i m\u011b\u0159en\u00ed DNA nedoch\u00e1z\u00ed k interferenci s RNA.<\/span><\/p>\n

Bez t\u00e9to kontroly Koenig a Kirchner \u201evytvo\u0159ili snadn\u00fd c\u00edl pro sv\u00e9 kritiky,\u201c \u0159ekl.<\/span><\/p>\n

Ve v\u00fdzkumu p\u0159ipravovan\u00e9m k publikaci McKernan uvedl, \u017ee n\u011bkolik laborato\u0159\u00ed, kter\u00e9 prov\u00e1d\u011bj\u00ed experimenty s RN\u00e1zou, zaznamenalo 10n\u00e1sobn\u00e9 sn\u00ed\u017een\u00ed sign\u00e1lu DNA ve fluorometrii.<\/span><\/p>\n

„To znamen\u00e1, \u017ee kontaminace DNA je st\u00e1le v\u00fdrazn\u011b nad limitem FDA [US Food and Drug Administration],“ \u0159\u00edk\u00e1 McKernan. Zd\u016fraznil, \u017ee jeho „vlasy trhaj\u00edc\u00ed kritika“ studie by nem\u011bla sni\u017eovat nebo vykolejovat v\u00fdzvy k p\u0159ehodnocen\u00ed testovac\u00edch protokol\u016f pro kontaminaci DNA mRNA vakc\u00edn.<\/span><\/p>\n

„U\u017e nediskutujeme o tom, zda jsou o\u010dkov\u00e1n\u00ed kontaminovan\u00e1,“ \u200b\u200b\u0159ekl. „Pr\u00e1v\u011b diskutujeme o tom, zda jsou 10 nebo 100kr\u00e1t nad limitem a jak moc se li\u0161\u00ed od \u0161ar\u017ee k \u0161ar\u017ei.“<\/span><\/p>\n

Mo\u017en\u00e1 rizika kontaminace DNA<\/strong><\/span><\/p>\n

K\u00f6nig a Kirchner vyj\u00e1d\u0159ili obavu, \u017ee by do lidsk\u00fdch bun\u011bk b\u011bhem vakcinace mohly b\u00fdt za\u010dlen\u011bny vy\u0161\u0161\u00ed \u00farovn\u011b kontaminace DNA, ne\u017e se o\u010dek\u00e1valo, s nezn\u00e1m\u00fdmi d\u016fsledky, pokud je tato DNA integrov\u00e1na do genomu.<\/span><\/p>\n

Citovali \u201eriziko inzer\u010dn\u00ed mutageneze\u201c, ve kter\u00e9 ciz\u00ed segmenty DNA naru\u0161uj\u00ed norm\u00e1ln\u00ed genov\u00e9 sekvence, kdy\u017e jsou vlo\u017eeny do genomu, co\u017e potenci\u00e1ln\u011b vede k mutac\u00edm a souvisej\u00edc\u00edm onemocn\u011bn\u00edm, jako je rakovina.<\/span><\/p>\n

V\u00fdzkumn\u00edci jako McKernan ji\u017e zjistili, \u017ee DNA v mRNA vakc\u00edn\u00e1ch COVID-19 obsahuje gen opi\u010d\u00edho viru 40 (SV40) podporuj\u00edc\u00ed rakovinu a sekvence DNA plazmidu E. coli, kter\u00e9 zbyly z v\u00fdroby vakc\u00edny.<\/span><\/p>\n

V prezentaci na konferenci International Crisis Summit-5 v \u00fanoru McKernan poznamenal, \u017ee Moderna ve sv\u00e9 patentov\u00e9 p\u0159ihl\u00e1\u0161ce na mRNA vakc\u00ednu COVID-19 uznala rizika inzer\u010dn\u00ed mutageneze.<\/span><\/p>\n

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Zdroj: Prezentace McKernan ICD 2024<\/em><\/figcaption><\/figure>\n<\/div>\n

Stejn\u00e1 patentov\u00e1 p\u0159ihl\u00e1\u0161ka uv\u00e1d\u00ed, \u017ee kontaminace DNA m\u016f\u017ee zp\u016fsobit rakovinu:<\/strong><\/p>\n

„DNA templ\u00e1t pou\u017e\u00edvan\u00fd v procesu v\u00fdroby mRNA mus\u00ed b\u00fdt odstran\u011bn, aby byla zaji\u0161t\u011bna terapeutick\u00e1 \u00fa\u010dinnost a bezpe\u010dnost, proto\u017ee zbytky DNA v l\u00e9\u010div\u00fdch p\u0159\u00edpravc\u00edch mohou vyvolat aktivaci vrozen\u00e9 reakce a maj\u00ed potenci\u00e1l b\u00fdt onkogenn\u00ed v populaci pacient\u016f.“<\/span><\/em><\/p>\n

McKernan ve sv\u00e9 prezentaci na Mezin\u00e1rodn\u00edm krizov\u00e9m summitu tvrdil, \u017ee \u201ev\u017edy p\u0159eru\u0161\u00edme\u201c. Navrhl n\u00e1sleduj\u00edc\u00ed \u201ehypot\u00e9zu t\u0159\u00ed z\u00e1sah\u016f\u201c o negativn\u00edch \u00fa\u010dinc\u00edch mRNA vakc\u00edn na zdrav\u00ed:<\/span><\/p>\n

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  1. Zv\u00fd\u0161en\u00e1 mutageneze p\u0159i kontaminaci plazmidu dsDNA [dvou\u0159et\u011bzcov\u00e1 DNA].<\/span><\/li>\n
  2. \u00da\u010dinky N1-methyl-pseudouridinu, pou\u017e\u00edvan\u00e9ho ke stabilizaci RNA, zp\u016fsobuj\u00edc\u00ed lymfocytopenii, neutropenii, onemocn\u011bn\u00ed souvisej\u00edc\u00ed s IgG4 atd.<\/span><\/li>\n
  3. Inhibice \u201estr\u00e1\u017ec\u016f genomu\u201c, tumor potla\u010duj\u00edc\u00edch gen\u016f P53 a BRCA1.<\/span><\/li>\n<\/ol>\n

    P\u0159edpisy o kontaminaci DNA \u201ezcela nevhodn\u00e9 pro dan\u00fd \u00fa\u010del\u201c<\/strong><\/span><\/p>\n

    McKernan zd\u016fraznil, \u017ee sou\u010dasn\u00e9 p\u0159edpisy o p\u0159\u00edpustn\u00e9m limitu kontaminace DNA ve vakc\u00edn\u00e1ch jsou \u201ezcela nedostate\u010dn\u00e9\u201c.<\/span><\/p>\n

    „Ve\u0159ejnost pot\u0159ebuje v\u011bd\u011bt, \u017ee sm\u011brnice o kontaminaci DNA p\u0159edpokl\u00e1daj\u00ed polo\u010das rozpadu nah\u00e9 DNA v krvi 5-10 minut,“ \u0159ekl. „Jakmile je tato DNA chr\u00e1n\u011bna lipidov\u00fdmi nano\u010d\u00e1sticemi, ji\u017e nen\u00ed nah\u00e1 a nedegraduje, ale sp\u00ed\u0161e transfekuje bu\u0148ky.“<\/span><\/p>\n

    Podle McKernana jsou fragmenty DNA zalo\u017een\u00e9 na savc\u00edch sou\u010d\u00e1st\u00ed \u201evysoce replikativn\u00edho vektoru pro genovou terapii navr\u017een\u00e9ho tak, aby produkoval v\u00edce sebe sama\u201c, a proto se mohou po transfekci neomezen\u011b mno\u017eit.<\/span><\/p>\n

    „K \u010demu je limit 10 ng, kdy\u017e farmaceutick\u00fd pr\u016fmysl m\u016f\u017ee propa\u0161ovat amplifikovatelnou molekulu DNA prost\u0159ednictv\u00edm tohoto na\u0159\u00edzen\u00ed,“ zeptal se.<\/span><\/p>\n

    Regul\u00e1to\u0159i stanovili limit 10 ng\/d\u00e1vku kontaminace DNA v roce 1998.<\/span><\/p>\n

    „10 ng je extracelul\u00e1rn\u00ed \u00favaha,“ \u0159ekl Karl Jablonowski, Ph.D., hlavn\u00ed v\u011bdec z Children’s Health Defense. „Pokud byste se zeptali, kolik ciz\u00ed DNA by m\u011blo b\u00fdt povoleno uvnit\u0159 bun\u011b\u010dn\u00e9ho j\u00e1dra, odpov\u011b\u010f by byla nula,“ \u0159ekl ochr\u00e1nci.<\/span><\/p>\n

    Speicher dodal, \u017ee regul\u00e1tory ignoruj\u00ed fragmenty men\u0161\u00ed ne\u017e 200 p\u00e1r\u016f b\u00e1z\u00ed, proto\u017ee by pravd\u011bpodobn\u011b nebyly problematick\u00e9, kdyby DNA z\u016fstala mimo na\u0161e bu\u0148ky.<\/span><\/p>\n

    Pro srovn\u00e1n\u00ed, DNA cel\u00e9ho lidsk\u00e9ho genomu m\u00e1 pr\u016fm\u011brnou velikost 6,41 pc (pikogram\u016f), co\u017e znamen\u00e1, \u017ee \u201e10 ng DNA tvo\u0159\u00ed 1560kr\u00e1t cel\u00fd n\u00e1\u0161 genom\u201c.<\/span><\/p>\n

    „Jak lehkomysln\u00ed mohou b\u00fdt s lidsk\u00fdm genomem?“<\/strong><\/span><\/p>\n

    Navzdory mo\u017en\u00fdm omezen\u00edm schv\u00e1lili evrop\u0161t\u00ed regul\u00e1to\u0159i metodu qPCR, aby ov\u011b\u0159ili, \u017ee Comirnaty spl\u0148uje po\u017eadovan\u00e9 limity kontaminace DNA 10 ng\/d\u00e1vku.<\/span><\/p>\n

    Podle K\u00f6niga a Kirchnera se krom\u011b test\u016f qPCR v\u00fdrobce pro \u00fa\u010dinnou l\u00e1tku \u201enebudou pro vakc\u00ednu prov\u00e1d\u011bt \u017e\u00e1dn\u00e9 dal\u0161\u00ed experiment\u00e1ln\u00ed kvantifikace DNA\u201c.<\/span><\/p>\n

    Regul\u00e1to\u0159i se domn\u00edvaj\u00ed, \u017ee testov\u00e1n\u00ed na kone\u010dn\u00e9m produktu nen\u00ed provediteln\u00e9, proto\u017ee lipidov\u00e9 nano\u010d\u00e1stice, ve kter\u00fdch je mRNA zapouzd\u0159ena, by mohly potenci\u00e1ln\u011b zp\u016fsobit interferenci.<\/span><\/p>\n

    V\u011bdci v\u0161ak pouk\u00e1zali na to, \u017ee v\u00fdrobci mohou p\u0159esn\u011b kvantifikovat mRNA v t\u011bchto stejn\u00fdch nano\u010d\u00e1stic\u00edch. Kritizovali regula\u010dn\u00ed org\u00e1ny za to, \u017ee se spol\u00e9haj\u00ed na omezen\u00e1 data qPCR v\u00fdrobc\u016f a nepo\u017eaduj\u00ed p\u0159\u00edmou kvantifikaci celkov\u00e9 DNA v kone\u010dn\u00e9m produktu Comirnaty.<\/span><\/p>\n

    Pot\u00e9, co dal\u0161\u00ed v\u011bdci replikovali McKernanovu pr\u00e1ci, byly regula\u010dn\u00ed agentury jako FDA, EMA a Health Canada nuceny uznat p\u0159\u00edtomnost SV40 ve vakc\u00edn\u00e1ch Pfizer.<\/span><\/p>\n

    McKernan v\u0161ak uvedl, \u017ee tyto \u00fa\u0159ady tvrd\u00ed, \u017ee fragmenty DNA jsou p\u0159\u00edli\u0161 mal\u00e9 na d\u00e9lku a mno\u017estv\u00ed na to, aby byly funk\u010dn\u00ed, a nepodnikly \u017e\u00e1dn\u00e9 kroky k dal\u0161\u00ed regulaci vakc\u00edn nebo jejich odstran\u011bn\u00ed z trhu.<\/span><\/p>\n

    McKernan tak\u00e9 pouk\u00e1zal na to, \u017ee p\u0159ed z\u00e1konem National Childhood Vaccine Injury Act z roku 1986 (NCVIA) byl limit pro kontaminaci DNA 1000kr\u00e1t ni\u017e\u0161\u00ed ne\u017e dne\u0161n\u00ed limit 10 ng.<\/span><\/p>\n

    Toto uvoln\u011bn\u00ed p\u0159edpis\u016f spolu s ochranou odpov\u011bdnosti NCVIA a technologick\u00fdm pokrokem u\u010dinilo technologii sekvenov\u00e1n\u00ed DNA \u201e100 000kr\u00e1t levn\u011bj\u0161\u00ed,\u201c \u0159ekl, a umo\u017enilo v\u00fdrobc\u016fm vakc\u00edn \u201ep\u0159id\u00e1vat transfek\u010dn\u00ed \u010dinidla [jako LNP], aby zajistili, \u017ee se DNA m\u016f\u017ee dostat bu\u0148ky, samy se reprodukuj\u00ed a manipuluj\u00ed s bun\u011b\u010dn\u00fdmi obvody.“<\/span><\/p>\n

    McKernan \u0159ekl:<\/strong><\/p>\n

    \u201ePro\u010d FDA tyto vakc\u00edny nesekvenuje? Jakou maj\u00ed v\u00fdmluvu, \u017ee neznaj\u00ed p\u0159esnou sekvenci a frekvenci ka\u017ed\u00e9 molekuly DNA a RNA ve vakc\u00edn\u011b, kterou pl\u00e1nuj\u00ed aplikovat miliard\u00e1m lid\u00ed? Jak neopatrn\u00ed mohou b\u00fdt s lidsk\u00fdm genomem?<\/span><\/em><\/p>\n

    Navzdory zjevn\u00e9 ne\u010dinnosti agentury odhalila ned\u00e1vn\u00e1 \u017e\u00e1dost o z\u00e1kon o svobod\u011b informac\u00ed od kanadsk\u00e9ho ob\u010dana \u201ealarmuj\u00edc\u00ed z\u00e1kulisn\u00ed aktivitu,\u201c \u0159ekl McKernan.<\/span><\/p>\n

    „Regul\u00e1to\u0159i \u0159\u00edkaj\u00ed ve\u0159ejnosti, aby se neb\u00e1la kontaminace, ale vyv\u00edjej\u00ed vnit\u0159n\u00ed \u00fasil\u00ed k odstran\u011bn\u00ed t\u00e9to DNA,“ \u0159ekl.<\/span><\/p>\n

    Autor: John Michael Dumais<\/em><\/p>\n<\/div>\n<\/div>\n

    \n
    \n

    ZDROJ<\/a><\/span><\/h3>\n

     <\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

    Nov\u00e1 recenzovan\u00e1 studie vyvol\u00e1v\u00e1 obavy z neadekv\u00e1tn\u00edch testovac\u00edch metod k m\u011b\u0159en\u00ed kontaminant\u016f DNA v mRNA…<\/p>\n","protected":false},"author":2,"featured_media":54176,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[23,895,694,651],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/54175"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=54175"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/54175\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/54176"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=54175"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=54175"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=54175"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}