{"id":53834,"date":"2024-05-17T00:33:47","date_gmt":"2024-05-16T22:33:47","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=53834"},"modified":"2024-05-16T15:12:35","modified_gmt":"2024-05-16T13:12:35","slug":"latka-objevena-na-velikonocnim-ostrove-prodluzuje-zivot-a-bojuje-proti-alzheimerove-chorobe","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2024\/05\/17\/latka-objevena-na-velikonocnim-ostrove-prodluzuje-zivot-a-bojuje-proti-alzheimerove-chorobe\/","title":{"rendered":"L\u00e1tka objeven\u00e1 na Velikono\u010dn\u00edm ostrov\u011b prodlu\u017euje \u017eivot a bojuje proti Alzheimerov\u011b chorob\u011b"},"content":{"rendered":"
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V\u011bdci si st\u00e1le l\u00e1mou hlavu nad l\u00e1tkou, kter\u00e1 byla objevena na Velikono\u010dn\u00edm ostrov\u011b p\u0159ed 50 lety. Rapamycin je produkov\u00e1n bakteriemi a jev\u00ed se jako siln\u00fd elix\u00edr \u017eivota. M\u016f\u017ee tak\u00e9 pomoci proti nemocem souvisej\u00edc\u00edm s v\u011bkem.<\/strong><\/p>\n

V roce 2009 byla zve\u0159ejn\u011bna p\u0159evratn\u00e1\u00a0<\/span>studie<\/span><\/a>\u00a0, kter\u00e1 uk\u00e1zala, \u017ee rapamycin prodlou\u017eil \u017eivot my\u0161\u00ed o 9 a\u017e 14 procent.<\/span><\/p>\n

V jin\u00e9\u00a0<\/span>studii<\/span><\/a>\u00a0byl my\u0161\u00edm pod\u00e1v\u00e1n rapamycin po dobu t\u0159\u00ed m\u011bs\u00edc\u016f. V pr\u016fm\u011bru se jim prodlou\u017eil \u017eivot o 60 procent.<\/span><\/p>\n

Droga m\u00e1 tak\u00e9 omlazuj\u00edc\u00ed \u00fa\u010dinek, m\u016f\u017ee stimulovat r\u016fst vlas\u016f a zabr\u00e1nit vypad\u00e1v\u00e1n\u00ed vlas\u016f. Pozitivn\u00ed \u00fa\u010dinky m\u00e1 tak\u00e9 p\u0159i l\u00e9\u010db\u011b nemoc\u00ed st\u00e1\u0159\u00ed jako je Alzheimer, cukrovka, srde\u010dn\u00ed a svalov\u00e9 nemoci.<\/span><\/p>\n

Minul\u00fd rok byla v\u00a0<\/span>GeroScience<\/span><\/a>\u00a0publikov\u00e1na studie 333 dosp\u011bl\u00fdch, kte\u0159\u00ed u\u017e\u00edvali rapamycin off-label .\u00a0Drtiv\u00e1 v\u011bt\u0161ina to vzala v boji proti st\u00e1rnut\u00ed, 19 procent jako prevenci demence.<\/span><\/p>\n

Rapamycin se nevyr\u00e1b\u00ed v laborato\u0159i, ale poch\u00e1z\u00ed z p\u0159\u00edrody, \u0159ekl profesor Robert Lufkin z University of Southern California.<\/span><\/p>\n

V prosinci 1964 cestoval na ostrov 40\u010dlenn\u00fd t\u00fdm veden\u00fd kanadsk\u00fdmi v\u011bdci, aby jej prozkoumal. Zjistili, \u017ee se u m\u00edstn\u00edch nikdy nevyvinul tetanus d\u00edky metabolitu Streptomyces hygroscopicus s antibakteri\u00e1ln\u00edmi vlastnostmi.<\/span><\/p>\n

L\u00e1tka zp\u016fsobuje odum\u00edr\u00e1n\u00ed pl\u00edsn\u00ed a okoln\u00edch p\u0159edm\u011bt\u016f a br\u00e1n\u00ed organism\u016fm v r\u016fstu, \u0159ekl Arlan Richardson, profesor z University of Oklahoma.<\/span><\/p>\n

Velikono\u010dn\u00ed ostrov se ve skute\u010dnosti jmenuje Rapa Nui, a proto se tam objeven\u00e1 l\u00e1tka pojmenovala \u201eRapamycin\u201c.<\/span><\/p>\n

Proto\u017ee inhibuje r\u016fst bun\u011bk, byl pozd\u011bji pou\u017e\u00edv\u00e1n jako l\u00e9k proti rakovin\u011b. Lufkin zjistil, \u017ee rapamycin p\u016fsob\u00ed proti n\u011bkolika typ\u016fm rakoviny.<\/span><\/p>\n

Podle profesora Andrey Maier z Vrije Universiteit Amsterdam p\u016fsob\u00ed rapamycin protiz\u00e1n\u011btliv\u011b a m\u00e1 pozitivn\u00ed \u00fa\u010dinky na kardiovaskul\u00e1rn\u00ed syst\u00e9m.<\/span><\/p>\n

Recenze<\/span><\/a>\u00a0publikovan\u00e1 v \u00fanoru v The Lancet Health Longevity\u00a0dosp\u011bla k z\u00e1v\u011bru, \u017ee u\u017e\u00edv\u00e1n\u00ed rapamycinu u zdrav\u00fdch lid\u00ed nezp\u016fsobuje z\u00e1va\u017en\u00e9 vedlej\u0161\u00ed \u00fa\u010dinky. V sou\u010dasnosti s t\u00edmto l\u00e9kem prob\u00edh\u00e1 t\u00e9m\u011b\u0159 100 klinick\u00fdch studi\u00ed.<\/span><\/p>\n<\/div>\n<\/div>\n

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ZDROJ<\/a><\/span><\/h3>\n

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V\u011bdci si st\u00e1le l\u00e1mou hlavu nad l\u00e1tkou, kter\u00e1 byla objevena na Velikono\u010dn\u00edm ostrov\u011b p\u0159ed 50…<\/p>\n","protected":false},"author":2,"featured_media":53835,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[7302,7301,7303,21],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/53834"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=53834"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/53834\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/53835"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=53834"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=53834"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=53834"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}