{"id":45383,"date":"2024-01-23T05:18:11","date_gmt":"2024-01-23T04:18:11","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=45383"},"modified":"2024-01-23T05:18:11","modified_gmt":"2024-01-23T04:18:11","slug":"vedci-ucinili-prulom-v-alzheimerove-chorobe","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2024\/01\/23\/vedci-ucinili-prulom-v-alzheimerove-chorobe\/","title":{"rendered":"V\u011bdci u\u010dinili pr\u016flom v Alzheimerov\u011b chorob\u011b"},"content":{"rendered":"
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Jednoduch\u00fd krevn\u00ed test by mohl odhalit biologick\u00e9 markery nemoci 15 let p\u0159ed rozvojem symptom\u016f, \u0159\u00edkaj\u00ed v\u011bdci<\/strong><\/span><\/p>\n

V\u011bdci uv\u00edtali potenci\u00e1ln\u011b \u201erevolu\u010dn\u00ed\u201c pr\u016flom v \u010dasn\u00e9 diagnostice Alzheimerovy choroby pot\u00e9, co t\u00fdm \u0161v\u00e9dsk\u00fdch v\u011bdc\u016f zjistil, \u017ee komer\u010dn\u011b dostupn\u00fd krevn\u00ed test dok\u00e1\u017ee detekovat biologick\u00e9 markery nemoci asi deset a\u017e 15 let p\u0159ed t\u00edm, ne\u017e se p\u0159\u00edznaky rozvinou.<\/span><\/p>\n

Ve studii 768 lid\u00ed ve v\u011bku kolem pades\u00e1ti, \u0161edes\u00e1ti a sedmdes\u00e1ti let b\u011bhem osmilet\u00e9ho obdob\u00ed, kterou provedla Univerzita v G\u00f6teborgu, bylo zji\u0161t\u011bno, \u017ee test, kter\u00fd zji\u0161\u0165uje p\u0159\u00edtomnost protein\u016f tau v krvi, byl 97% p\u0159esn\u00fd p\u0159i hodnocen\u00ed. pokud byl subjekt n\u00e1chyln\u00fd k rozvoji onemocn\u011bn\u00ed.<\/span><\/p>\n

V\u00fdsledky studie, zve\u0159ejn\u011bn\u00e9 v pond\u011bl\u00ed v \u010dasopise JAMA Neurology, byly oslavov\u00e1ny jako pr\u016flom v \u010dasn\u00fdch screeningov\u00fdch testech na tuto nemoc v dostate\u010dn\u00e9m p\u0159edstihu p\u0159ed n\u00e1stupem p\u0159\u00edznak\u016f.<\/span><\/p>\n

Alzheimerova choroba, kter\u00e1 zp\u016fsobuje zmen\u0161ov\u00e1n\u00ed mozku a nakonec odum\u00edr\u00e1n\u00ed jeho bun\u011bk, je nejb\u011b\u017en\u011bj\u0161\u00ed formou demence a je charakterizov\u00e1na poklesem kognitivn\u00edch funkc\u00ed, chov\u00e1n\u00ed a soci\u00e1ln\u00edch dovednost\u00ed.<\/span><\/p>\n

V\u00fdzkum\u00a0<\/span>\u201ep\u0159id\u00e1v\u00e1 k rostouc\u00edmu mno\u017estv\u00ed d\u016fkaz\u016f, \u017ee tento konkr\u00e9tn\u00ed test m\u00e1 obrovsk\u00fd potenci\u00e1l zp\u016fsobit revoluci v diagnostikov\u00e1n\u00ed u lid\u00ed s podez\u0159en\u00edm na Alzheimerovu chorobu,\u201c<\/span><\/em>\u00a0\u0159ekla v pond\u011bl\u00ed Sheona Scales, \u0159editelka v\u00fdzkumu Alzheimer’s Research UK, podle The Times.<\/span><\/p>\n

Dodala, \u017ee testov\u00e1n\u00ed je\u00a0<\/span>\u201elep\u0161\u00ed ne\u017e \u0159ada dal\u0161\u00edch test\u016f, kter\u00e9 jsou v sou\u010dasn\u00e9 dob\u011b ve v\u00fdvoji\u201c<\/span><\/em>\u00a0a je vhodn\u011bj\u0161\u00ed ne\u017e invazivn\u011bj\u0161\u00ed metody, kter\u00e9 v sou\u010dasnosti pou\u017e\u00edvaj\u00ed l\u00e9ka\u0159i, jako jsou lumb\u00e1ln\u00ed punkce.<\/span><\/p>\n

David Curtis z UCL Genetics Institute uvedl, \u017ee zji\u0161t\u011bn\u00ed \u0161v\u00e9dsk\u00e9ho t\u00fdmu v\u011bdc\u016f\u00a0<\/span>\u201emohou m\u00edt obrovsk\u00e9 d\u016fsledky\u201c.<\/span><\/em><\/p>\n

„Ka\u017ed\u00fd, kdo je star\u0161\u00ed 50 let, by mohl b\u00fdt rutinn\u011b vy\u0161et\u0159ov\u00e1n ka\u017ed\u00fdch n\u011bkolik let, v podstat\u011b stejn\u00fdm zp\u016fsobem, jako je nyn\u00ed vy\u0161et\u0159ov\u00e1n na vysok\u00fd cholesterol,“<\/span><\/em>\u00a0dodal.\u00a0<\/span>„Je mo\u017en\u00e9, \u017ee v sou\u010dasn\u00e9 dob\u011b dostupn\u00e9 l\u00e9\u010dby Alzheimerovy choroby by fungovaly l\u00e9pe u t\u011bch, kte\u0159\u00ed jsou takto v\u010das diagnostikov\u00e1ni.“<\/span><\/em><\/p>\n

V\u00fdvoj\u00e1\u0159 krevn\u00edho testu, kalifornsk\u00e1 spole\u010dnost ALZpath, uvedla, \u017ee douf\u00e1, \u017ee test bude \u0161iroce dostupn\u00fd pro klinick\u00e9 pou\u017eit\u00ed v prvn\u00edm \u010dtvrtlet\u00ed tohoto roku.<\/span><\/p>\n

Asi 1 z 9 lid\u00ed (10,7 %) ve v\u011bku 65 a v\u00edce let trp\u00ed touto nemoc\u00ed, podle \u00fadaj\u016f Asociace Alzheimerovy choroby.\u00a0O\u010dek\u00e1v\u00e1 se, \u017ee toto \u010d\u00edslo v p\u0159\u00ed\u0161t\u00edch 25 letech podstatn\u011b vzroste, uv\u00e1d\u00ed skupina na sv\u00fdch webov\u00fdch str\u00e1nk\u00e1ch,\u00a0<\/span>„s v\u00fdjimkou v\u00fdvoje l\u00e9ka\u0159sk\u00fdch objev\u016f k prevenci nebo l\u00e9\u010db\u011b Alzheimerovy choroby.“<\/span><\/em><\/p>\n

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Jednoduch\u00fd krevn\u00ed test by mohl odhalit biologick\u00e9 markery nemoci 15 let p\u0159ed rozvojem symptom\u016f, \u0159\u00edkaj\u00ed…<\/p>\n","protected":false},"author":2,"featured_media":45384,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[2958,1561,21],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/45383"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=45383"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/45383\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/45384"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=45383"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=45383"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=45383"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}