{"id":119504,"date":"2026-10-27T00:31:35","date_gmt":"2026-10-26T23:31:35","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=119504"},"modified":"2026-10-26T18:56:28","modified_gmt":"2026-10-26T17:56:28","slug":"nejnovejsi-zprava-nova-studie-ukazuje-jak-by-se-mrna-materialy-vakcin-mohly-prenaset-z-ockovanych-na-neockovane-osoby","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2026\/10\/27\/nejnovejsi-zprava-nova-studie-ukazuje-jak-by-se-mrna-materialy-vakcin-mohly-prenaset-z-ockovanych-na-neockovane-osoby\/","title":{"rendered":"Nejnov\u011bj\u0161\u00ed zpr\u00e1va: Nov\u00e1 studie ukazuje, jak by se mRNA materi\u00e1ly vakc\u00edn mohly p\u0159en\u00e1\u0161et z o\u010dkovan\u00fdch na neo\u010dkovan\u00e9 osoby"},"content":{"rendered":"
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Lid\u00e9 na cel\u00e9m sv\u011bt\u011b ji\u017e l\u00e9ta vyjad\u0159uj\u00ed v\u00e1\u017en\u00e9 obavy z uvol\u0148ov\u00e1n\u00ed mRNA z vakc\u00edn \u2013 tedy z mo\u017enosti, \u017ee by se materi\u00e1ly z\u00edskan\u00e9 z vakc\u00edny mohly roz\u0161\u00ed\u0159it i mimo osoby, kter\u00e9 injekce dostaly. Navzdory l\u00e9t\u016fm ve\u0159ejn\u00fdch obav a debat z\u016fst\u00e1vaj\u00ed z\u00e1sadn\u00ed ot\u00e1zky t\u00fdkaj\u00edc\u00ed se t\u00e9to mo\u017enosti nezodpov\u011bzeny.<\/span><\/p>\n

Rozhodli jsme se komplexn\u011b prozkoumat v\u011bdeck\u00e9 d\u016fkazy a sledovat, co se d\u011bje s materi\u00e1ly z\u00edskan\u00fdmi z vakc\u00edn v t\u011ble, jak se \u0161\u00ed\u0159\u00ed mezi bu\u0148kami a zda existuj\u00ed biologick\u00e9 mechanismy, kter\u00e9 by mohly umo\u017enit p\u0159enos t\u011bchto materi\u00e1l\u016f z jedn\u00e9 osoby na druhou.<\/span><\/p>\n

N\u00e1\u0161 v\u00fdsledn\u00fd \u010dl\u00e1nek s n\u00e1zvem <\/span>\u201e <\/span>Uvol\u0148ov\u00e1n\u00ed mRNA vakc\u00edn: vnit\u0159n\u00ed transkrip\u010dn\u00ed \u0161\u00ed\u0159en\u00ed a potenci\u00e1ln\u00ed p\u0159enos z \u010dlov\u011bka na \u010dlov\u011bka<\/span><\/a> \u201c<\/span><\/strong> byl spoluautory Johna A. Catanzara, NMD, PhD, ze spole\u010dnosti Neo7Bioscience, Inc., Nicolase Hulschera, MPH (j\u00e1) a Petera A. McCullougha, MD, MPH, z McCullough Foundation.<\/span><\/p>\n

Na z\u00e1klad\u011b publikovan\u00fdch studi\u00ed na lidech, molekul\u00e1rn\u00edch experiment\u016f a v\u00fdzkumu extracelul\u00e1rn\u00edch vezikul jsme prozkoumali dostupn\u00e9 d\u016fkazy a identifikovali dv\u011b r\u016fzn\u00e9 formy uvol\u0148ov\u00e1n\u00ed mRNA z vakc\u00edny:<\/span><\/p>\n

1. P\u0159enos z \u010dlov\u011bka na \u010dlov\u011bka:<\/span><\/strong> Mo\u017en\u00fd p\u0159enos materi\u00e1l\u016f z\u00edskan\u00fdch z vakc\u00edny prost\u0159ednictv\u00edm biologick\u00fdch sekret\u016f z o\u010dkovan\u00fdch jedinc\u016f na jin\u00e9 lidi.<\/span><\/p>\n

2. Transkrip\u010dn\u00ed uvol\u0148ov\u00e1n\u00ed:<\/span><\/strong> Produkce, fragmentace, perzistence a vnit\u0159n\u00ed distribuce molekul\u00e1rn\u00edch produkt\u016f odvozen\u00fdch z vakc\u00edny v cel\u00e9m t\u011ble.<\/span><\/p>\n

\"\"<\/figure>\n

1. P\u0159enos z \u010dlov\u011bka na \u010dlov\u011bka: Mo\u017en\u00fd p\u0159enos mezi jednotlivci<\/span><\/h2>\n

Studie detekovaly spike protein a mRNA odvozen\u00e9 z vakc\u00edny na nebo v cirkuluj\u00edc\u00edch exosomech n\u011bkolik let po o\u010dkov\u00e1n\u00ed. Exosomy jsou mikroskopick\u00e9, membr\u00e1nov\u011b v\u00e1zan\u00e9 \u010d\u00e1stice, kter\u00e9 chr\u00e1n\u00ed a transportuj\u00ed proteiny, genetick\u00fd materi\u00e1l a dal\u0161\u00ed biologick\u00fd n\u00e1klad mezi bu\u0148kami.<\/span><\/p>\n

Je d\u016fle\u017eit\u00e9 si uv\u011bdomit, \u017ee stejn\u00e9 typy \u010d\u00e1stic se p\u0159irozen\u011b vyskytuj\u00ed v t\u011blesn\u00fdch sekretech, kter\u00e9 mohou p\u0159ij\u00edt do kontaktu s jin\u00fdmi lidmi:<\/span><\/p>\n

Mate\u0159sk\u00e9 ml\u00e9ko:<\/span><\/strong> mRNA odvozen\u00e1 z vakc\u00edny ji\u017e byla detekov\u00e1na v exosomech lidsk\u00e9ho mate\u0159sk\u00e9ho ml\u00e9ka. To potvrzuje p\u0159\u00edtomnost genetick\u00e9ho materi\u00e1lu vakc\u00edny v sekretu, kter\u00fd se p\u0159irozen\u011b p\u0159en\u00e1\u0161\u00ed z o\u010dkovan\u00fdch matek na jejich d\u011bti.<\/span><\/p>\n

Sliny:<\/span><\/strong> V lidsk\u00fdch slin\u00e1ch byly detekov\u00e1ny exosomy, ale dosud nebylo zkoum\u00e1no, zda mohou transportovat spike protein, mRNA nebo plazmidovou DNA poch\u00e1zej\u00edc\u00ed z vakc\u00edny.<\/span><\/p>\n

Vydechovan\u00fd vzduch:<\/span><\/strong> Exosomy a dal\u0161\u00ed extracelul\u00e1rn\u00ed vezikuly byly extrahov\u00e1ny z vydechovan\u00e9ho vzduchu a respira\u010dn\u00edho kondenz\u00e1tu. Zda tyto \u010d\u00e1stice transportuj\u00ed materi\u00e1ly odvozen\u00e9 z vakc\u00edny po vakcinaci mRNA, nebylo p\u0159\u00edmo zkoum\u00e1no.<\/span><\/p>\n

Pot:<\/span><\/strong> Extracelul\u00e1rn\u00ed vezikuly byly tak\u00e9 detekov\u00e1ny v lidsk\u00e9m potu, ale dosud nebylo zkoum\u00e1no, zda mohou transportovat molekul\u00e1rn\u00ed produkty poch\u00e1zej\u00edc\u00ed z vakc\u00edny.<\/span><\/p>\n

Exosomy nejsou jen pasivn\u00edmi kontejnery. Experiment\u00e1ln\u00ed v\u00fdzkum ukazuje, \u017ee dok\u00e1\u017e\u00ed chr\u00e1nit genetick\u00fd materi\u00e1l, pronikat do bun\u011bk p\u0159\u00edjemce a doru\u010dovat molekul\u00e1rn\u00ed n\u00e1klad, kter\u00fd m\u016f\u017ee m\u011bnit bun\u011b\u010dnou aktivitu.<\/span><\/p>\n

Tato zji\u0161t\u011bn\u00ed poskytuj\u00ed v\u011brohodn\u00fd biologick\u00fd z\u00e1klad pro cesty p\u0159enosu z \u010dlov\u011bka na \u010dlov\u011bka, kter\u00e9 sahaj\u00ed i za hranice mate\u0159sk\u00e9ho ml\u00e9ka.<\/span><\/p>\n

Krom\u011b t\u011bchto obav zjistila observa\u010dn\u00ed studie s tis\u00edci respondentkami korelaci mezi bl\u00edzkost\u00ed o\u010dkovan\u00fdch osob a menstrua\u010dn\u00edmi nepravidelnostmi u neo\u010dkovan\u00fdch \u017een.<\/span><\/p>\n

Navzdory t\u011bmto pozorov\u00e1n\u00edm nebylo nikdy p\u0159\u00edmo zkoum\u00e1no, zda se spike protein, mRNA nebo plazmidov\u00e1 DNA odvozen\u00e1 z vakc\u00edny m\u016f\u017ee p\u0159en\u00e1\u0161et mezi jednotlivci prost\u0159ednictv\u00edm slin, vydechovan\u00e9ho vzduchu, potu nebo jin\u00fdch t\u011blesn\u00fdch sekret\u016f krom\u011b ml\u00e9ka.<\/span><\/p>\n

2. Transkrip\u010dn\u00ed uvol\u0148ov\u00e1n\u00ed: vnit\u0159n\u00ed \u0161\u00ed\u0159en\u00ed po cel\u00e9m t\u011ble<\/span><\/h2>\n

Druh\u00e1 forma uvol\u0148ov\u00e1n\u00ed, kterou jsme v na\u0161\u00ed pr\u00e1ci zkoumali, se t\u00fdk\u00e1 produkce, fragmentace, perzistence a \u0161\u00ed\u0159en\u00ed molekul\u00e1rn\u00edch materi\u00e1l\u016f odvozen\u00fdch z vakc\u00edny v o\u010dkovan\u00e9 osob\u011b.<\/span><\/p>\n

Po o\u010dkov\u00e1n\u00ed mRNA lidsk\u00e9 bu\u0148ky produkuj\u00ed spike protein SARS-CoV-2. Tento protein m\u016f\u017ee b\u00fdt enzymatick\u00fdmi procesy rozlo\u017een na fragmenty, uvoln\u011bn do krevn\u00edho ob\u011bhu a transportov\u00e1n v t\u011ble v exosomech nebo na jejich povrchu.<\/span><\/p>\n

Zkoum\u00e1me dva dal\u0161\u00ed mechanismy, kter\u00e9 by mohly tento proces prodlou\u017eit.<\/span><\/p>\n

Bun\u011b\u010dn\u00e9 d\u011blen\u00ed (mit\u00f3za):<\/span><\/strong> Kdy\u017e se bu\u0148ky obsahuj\u00edc\u00ed proteiny odvozen\u00e9 z vakc\u00edny d\u011bl\u00ed, jejich dce\u0159in\u00e9 bu\u0148ky mohou p\u0159evz\u00edt \u010d\u00e1sti modifikovan\u00e9ho bun\u011b\u010dn\u00e9ho obsahu. Tento navrhovan\u00fd mechanismus by mohl umo\u017enit materi\u00e1l\u016fm odvozen\u00fdm z vakc\u00edny p\u0159etrv\u00e1vat a vyv\u00edjet biologick\u00e9 \u00fa\u010dinky nap\u0159\u00ed\u010d po sob\u011b jdouc\u00edmi bun\u011b\u010dn\u00fdmi generacemi.<\/span><\/p>\n

\u0160\u00ed\u0159en\u00ed z bu\u0148ky do bu\u0148ky:<\/span><\/strong> Exosomy mohou transportovat materi\u00e1ly souvisej\u00edc\u00ed s hroty a regula\u010dn\u00ed genetick\u00fd n\u00e1klad do vzd\u00e1len\u00fdch bun\u011bk, kter\u00e9 nikdy p\u0159\u00edmo neobdr\u017eely mRNA z vakc\u00edny. Experiment\u00e1ln\u00ed studie s bu\u0148kami exprimuj\u00edc\u00edmi hroty ukazuj\u00ed, \u017ee exosomov\u00fd n\u00e1klad m\u016f\u017ee zm\u011bnit sign\u00e1ln\u00ed dr\u00e1hy v bu\u0148k\u00e1ch p\u0159\u00edjemce.<\/span><\/p>\n

Tyto mechanismy dohromady nazna\u010duj\u00ed potenci\u00e1ln\u011b samoposiluj\u00edc\u00ed cyklus molekul\u00e1rn\u00edho \u0161\u00ed\u0159en\u00ed a naru\u0161en\u00ed bun\u011b\u010dn\u00e9 signalizace:<\/span><\/p>\n

Produkce hrot\u016f, fragmentace protein\u016f, uvoln\u011bn\u00ed exosom\u016f, naru\u0161en\u00ed bun\u011b\u010dn\u00e9 signalizace, dal\u0161\u00ed \u0161\u00ed\u0159en\u00ed<\/span><\/strong><\/p>\n

Jak se materi\u00e1ly odvozen\u00e9 od vakc\u00edn \u0161\u00ed\u0159\u00ed mezi bu\u0148kami, naru\u0161uj\u00ed p\u011bt vz\u00e1jemn\u011b propojen\u00fdch biologick\u00fdch syst\u00e9m\u016f: sr\u00e1\u017een\u00ed krve, rozpozn\u00e1v\u00e1n\u00ed vrozen\u00e9 imunity, signalizaci supresor\u016f n\u00e1dor\u016f, regulaci bun\u011b\u010dn\u00fdch receptor\u016f a signalizaci interferonu.<\/span><\/p>\n

\"\"<\/figure>\n

Mo\u017enost trval\u00e9ho naru\u0161en\u00ed bun\u011bk a p\u0159enosu mRNA vakc\u00ednov\u00e9ho materi\u00e1lu z \u010dlov\u011bka na \u010dlov\u011bka vy\u017eaduje okam\u017eit\u00e9 vy\u0161et\u0159en\u00ed. Do t\u00e9 doby je zastaven\u00ed technologie mRNA opodstatn\u011bn\u00e9, aby se ochr\u00e1nili nez\u00fa\u010dastn\u011bn\u00ed jedinci p\u0159ed potenci\u00e1ln\u00edm \u0161\u00ed\u0159en\u00edm.<\/span><\/p>\n

od <\/span>Nicolase Hulschera, MPH<\/span><\/strong><\/em><\/p>\n<\/div>\n<\/div>\n

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Zdroj<\/span><\/a><\/span><\/h3>\n

 <\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Lid\u00e9 na cel\u00e9m sv\u011bt\u011b ji\u017e l\u00e9ta vyjad\u0159uj\u00ed v\u00e1\u017en\u00e9 obavy z uvol\u0148ov\u00e1n\u00ed mRNA z vakc\u00edn \u2013…<\/p>\n","protected":false},"author":2,"featured_media":78316,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[694,11920,1681,651],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/119504"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=119504"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/119504\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/78316"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=119504"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=119504"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=119504"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}