{"id":119357,"date":"2026-10-26T00:12:27","date_gmt":"2026-10-25T23:12:27","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=119357"},"modified":"2026-10-25T12:27:24","modified_gmt":"2026-10-25T11:27:24","slug":"vedci-odhalili-slabinu-beznych-testu-cholesterolu-prehlizeji-dulezita-rizika-pro-srdce","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2026\/10\/26\/vedci-odhalili-slabinu-beznych-testu-cholesterolu-prehlizeji-dulezita-rizika-pro-srdce\/","title":{"rendered":"V\u011bdci odhalili slabinu b\u011b\u017en\u00fdch test\u016f cholesterolu: P\u0159ehl\u00ed\u017eej\u00ed d\u016fle\u017eit\u00e1 rizika pro srdce"},"content":{"rendered":"<div id=\"fb-root\"><\/div>\n<p><strong><span dir=\"auto\">M\u00e1te cholesterol v norm\u011b a mysl\u00edte si, \u017ee va\u0161e srdce je v bezpe\u010d\u00ed? Nov\u00fd v\u00fdzkum ukazuje, \u017ee b\u011b\u017en\u00e9 krevn\u00ed testy nemus\u00ed odhalit v\u0161echna rizika.<\/span><\/strong><\/p>\n<p><span dir=\"auto\">V\u011bdci zjistili, \u017ee p\u0159i vzniku srde\u010dn\u00edch onemocn\u011bn\u00ed hraj\u00ed d\u016fle\u017eitou roli tak\u00e9 z\u00e1n\u011btliv\u00e9 procesy a zm\u011bny ve st\u011bn\u00e1ch c\u00e9v, kter\u00e9 samotn\u00e9 m\u011b\u0159en\u00ed cholesterolu nezachyt\u00ed.<\/span><\/p>\n<p><a href=\"https:\/\/academic.oup.com\/eurheartj\/advance-article\/doi\/10.1093\/eurheartj\/ehag718\/8772973\" target=\"_blank\" rel=\"noopener\"><span dir=\"auto\">Studie<\/span><\/a><span dir=\"auto\"> zahrnuj\u00edc\u00ed v\u00edce ne\u017e 35 000 \u00fa\u010dastn\u00edk\u016f britsk\u00e9 biobanky p\u0159inesla pozoruhodn\u00e9 zji\u0161t\u011bn\u00ed. <\/span><strong><span dir=\"auto\">B\u00edlkoviny spojen\u00e9 se z\u00e1n\u011btem a p\u0159estavbou c\u00e9v vysv\u011btlovaly p\u0159ibli\u017en\u011b 62 % souvislosti mezi lipoproteiny bohat\u00fdmi na triglyceridy a rizikem ischemick\u00e9 choroby srde\u010dn\u00ed.<\/span><\/strong><\/p>\n<p><span dir=\"auto\">V\u00fdsledky nazna\u010duj\u00ed, \u017ee p\u0159i hodnocen\u00ed zdrav\u00ed srdce bychom se nem\u011bli spol\u00e9hat pouze na b\u011b\u017en\u00e9 hodnoty cholesterolu. D\u016fle\u017eit\u00e9 informace poskytuj\u00ed i \u200b\u200bdal\u0161\u00ed krevn\u00ed ukazatele, zejm\u00e9na apolipoprotein B (apoB) a lipoprotein(a), ozna\u010dovan\u00fd jako Lp(a).<\/span><\/p>\n<h2><span dir=\"auto\">Studie zkoumala t\u0159i druhy krevn\u00edch tuk\u016f<\/span><\/h2>\n<p><span dir=\"auto\">V\u011bdci analyzovali krevn\u00ed vzorky 35 269 \u00fa\u010dastn\u00edk\u016f britsk\u00e9 biobanky, kte\u0159\u00ed na za\u010d\u00e1tku v\u00fdzkumu nem\u011bli diagnostikov\u00e1no srde\u010dn\u011b-c\u00e9vn\u00ed onemocn\u011bn\u00ed. V\u00fdsledky n\u00e1sledn\u011b ov\u011b\u0159ili na dal\u0161\u00edch 5 915 \u00fa\u010dastn\u00edc\u00edch americk\u00e9 studie.<\/span><\/p>\n<p><span dir=\"auto\">Zam\u011b\u0159ili se na t\u0159i skupiny lipoprotein\u016f, tedy \u010d\u00e1stic, kter\u00e9 p\u0159en\u00e1\u0161ej\u00ed tuky a cholesterol v krvi:<\/span><\/p>\n<ul>\n<li><strong><span dir=\"auto\">LDL (lipoproteiny o n\u00edzk\u00e9 hustot\u011b)<\/span><\/strong><span dir=\"auto\"> \u2013 zn\u00e1m\u00e9 jako \u201e\u0161patn\u00fd cholesterol\u201c. P\u0159i zv\u00fd\u0161en\u00fdch hladin\u00e1ch p\u0159isp\u00edvaj\u00ed k ukl\u00e1d\u00e1n\u00ed cholesterolu ve st\u011bn\u00e1ch tepen.<\/span><\/li>\n<li><strong><span dir=\"auto\">TRL (lipoproteiny bohat\u00e9 na triglyceridy)<\/span><\/strong><span dir=\"auto\"> \u2013 \u010d\u00e1stice p\u0159en\u00e1\u0161ej\u00edc\u00ed zejm\u00e9na triglyceridy, tedy tuky, kter\u00e9 t\u011blo vyu\u017e\u00edv\u00e1 jako zdroj energie nebo si je ukl\u00e1d\u00e1 do z\u00e1soby.<\/span><\/li>\n<li><strong><span dir=\"auto\">Lp(a) \u2013 lipoprotein(a)<\/span><\/strong><span dir=\"auto\"> \u2013 zvl\u00e1\u0161tn\u00ed druh lipoproteinu, jeho\u017e hladina je p\u0159ev\u00e1\u017en\u011b d\u011bdi\u010dn\u00e1. Zv\u00fd\u0161en\u00e9 hodnoty p\u0159edstavuj\u00ed dal\u0161\u00ed rizikov\u00fd faktor srde\u010dn\u00edch onemocn\u011bn\u00ed.<\/span><\/li>\n<\/ul>\n<p><span dir=\"auto\">V\u00fdzkumn\u00edci zkoumali t\u00e9m\u011b\u0159 3 000 krevn\u00edch b\u00edlkovin, aby zjistili, jak\u00e9 biologick\u00e9 procesy jednotliv\u00e9 skupiny lipoprotein\u016f ovliv\u0148uj\u00ed.<\/span><\/p>\n<p><span dir=\"auto\">Uk\u00e1zalo se, \u017ee b\u00edlkoviny spojen\u00e9 s LDL se pod\u00edlely p\u0159edev\u0161\u00edm na p\u0159enosu a zpracov\u00e1n\u00ed cholesterolu. P\u0159i TRL a Lp(a) v\u0161ak v\u011bdci odhalili tak\u00e9 v\u00fdrazn\u00e9 propojen\u00ed se z\u00e1n\u011btliv\u00fdmi procesy, aktivitou imunitn\u00edho syst\u00e9mu a zm\u011bnami c\u00e9vn\u00edch st\u011bn.<\/span><\/p>\n<p><span dir=\"auto\">V\u011bdci v\u00fdsledky prov\u011b\u0159ili tak\u00e9 genetickou anal\u00fdzou, kter\u00e1 pom\u00e1h\u00e1 odhalit mo\u017en\u00e9 p\u0159\u00ed\u010dinn\u00e9 souvislosti, a t\u00edm l\u00e9pe pochopit mechanismy vzniku srde\u010dn\u00edch onemocn\u011bn\u00ed.<\/span><\/p>\n<h2><span dir=\"auto\">Z\u00e1n\u011bt a zm\u011bny c\u00e9v vysv\u011btluj\u00ed v\u00fdznamnou \u010d\u00e1st rizika<\/span><\/h2>\n<p><span dir=\"auto\">Jedn\u00edm z nejd\u016fle\u017eit\u011bj\u0161\u00edch zji\u0161t\u011bn\u00ed bylo, \u017ee <\/span><strong><span dir=\"auto\">z\u00e1n\u011btliv\u00e9 procesy a p\u0159estavba c\u00e9vn\u00edch st\u011bn vysv\u011btlovaly v\u00fdznamnou \u010d\u00e1st souvislosti mezi ur\u010dit\u00fdmi lipoproteiny a rizikem srde\u010dn\u00edch onemocn\u011bn\u00ed<\/span><\/strong><span dir=\"auto\"> . U lipoproteinu(a) \u010dinil tento pod\u00edl p\u0159ibli\u017en\u011b 14 %.<\/span><\/p>\n<p><span dir=\"auto\">Tato procenta vyjad\u0159uj\u00ed, jakou \u010d\u00e1st souvislosti mezi jednotliv\u00fdmi lipoproteiny a srde\u010dn\u00edmi onemocn\u011bn\u00edmi vysv\u011btlovaly zkouman\u00e9 z\u00e1n\u011btliv\u00e9 a c\u00e9vn\u00ed procesy.<\/span><\/p>\n<p><span dir=\"auto\">Zaj\u00edmav\u00e9 je, \u017ee tyto procesy nebyly zcela zachyceny ani pomoc\u00ed C-reaktivn\u00edho proteinu (CRP), kter\u00fd l\u00e9ka\u0159i b\u011b\u017en\u011b pou\u017e\u00edvaj\u00ed jako ukazatel z\u00e1n\u011btu v organismu.<\/span><\/p>\n<p><span dir=\"auto\">To nazna\u010duje, \u017ee <\/span><strong><span dir=\"auto\">v c\u00e9v\u00e1ch mohou prob\u00edhat d\u016fle\u017eit\u00e9 z\u00e1n\u011btliv\u00e9 procesy, kter\u00e9 samotn\u00e1 hodnota CRP dostate\u010dn\u011b nevystihuje<\/span><\/strong><span dir=\"auto\"> .<\/span><\/p>\n<p><span dir=\"auto\">Dal\u0161\u00edm p\u0159ekvapen\u00edm bylo srovn\u00e1n\u00ed jednotliv\u00fdch skupin lipoprotein\u016f. I po zohledn\u011bn\u00ed hladin LDL, TRL a Lp(a) z\u016fstaly b\u00edlkoviny spojen\u00e9 s TRL a Lp(a) v\u00fdznamn\u00fdmi ukazateli rizika ischemick\u00e9 choroby srde\u010dn\u00ed. U b\u00edlkovin souvisej\u00edc\u00edch s LDL se takov\u00e1 nez\u00e1visl\u00e1 souvislost ji\u017e nepotvrdila.<\/span><\/p>\n<p><span dir=\"auto\">LDL cholesterol p\u0159itom z\u016fst\u00e1v\u00e1 v\u00fdznamn\u00fdm rizikov\u00fdm faktorem ateroskler\u00f3zy. V\u00fdzkum v\u0161ak uk\u00e1zal, \u017ee dal\u0161\u00ed lipoproteiny souvis\u00ed tak\u00e9 s biologick\u00fdmi procesy, kter\u00e9 p\u0159esahuj\u00ed samotn\u00e9 ukl\u00e1d\u00e1n\u00ed cholesterolu do c\u00e9vn\u00edch st\u011bn.<\/span><\/p>\n<h2><span dir=\"auto\">Co standardn\u00ed testy cholesterolu p\u0159ehl\u00ed\u017eej\u00ed<\/span><\/h2>\n<p><span dir=\"auto\">B\u011b\u017en\u00e9 vy\u0161et\u0159en\u00ed tuk\u016f v krvi zpravidla zahrnuje celkov\u00fd cholesterol, LDL, HDL a triglyceridy. Tyto hodnoty jsou u\u017eite\u010dn\u00e9, ale poskytuj\u00ed pouze \u010d\u00e1st obrazu o kardiovaskul\u00e1rn\u00edm riziku.<\/span><\/p>\n<p><span dir=\"auto\">Jedn\u00edm z d\u016fle\u017eit\u00fdch dopl\u0148kov\u00fdch ukazatel\u016f je <\/span><strong><span dir=\"auto\">apolipoprotein B (apoB)<\/span><\/strong><span dir=\"auto\"> . Jedn\u00e1 se o b\u00edlkovinu, kter\u00e1 se nach\u00e1z\u00ed na povrchu LDL a dal\u0161\u00edch \u010d\u00e1stic podporuj\u00edc\u00edch ateroskler\u00f3zu. Jej\u00ed mno\u017estv\u00ed pom\u00e1h\u00e1 odhadnout po\u010det t\u011bchto rizikov\u00fdch \u010d\u00e1stic v krvi.<\/span><\/p>\n<p><span dir=\"auto\">Dv\u011b osoby tak mohou m\u00edt podobnou hladinu LDL cholesterolu, ale rozd\u00edln\u00fd po\u010det \u010d\u00e1stic, kter\u00e9 jej p\u0159en\u00e1\u0161ej\u00ed. Vy\u0161et\u0159en\u00ed apoB tento rozd\u00edl dok\u00e1\u017ee odhalit.<\/span><\/p>\n<p><span dir=\"auto\">Dal\u0161\u00edm d\u016fle\u017eit\u00fdm ukazatelem je Lp(a). Jeho hladinu do velk\u00e9 m\u00edry ur\u010duj\u00ed geny, tak\u017ee i \u010dlov\u011bk, kter\u00fd se zdrav\u011b stravuje, pravideln\u011b cvi\u010d\u00ed a m\u00e1 p\u0159\u00edzniv\u00e9 hodnoty LDL, m\u016f\u017ee m\u00edt zv\u00fd\u0161en\u00e9 riziko srde\u010dn\u00edch onemocn\u011bn\u00ed.<\/span><\/p>\n<p><span dir=\"auto\">Pr\u00e1v\u011b proto se st\u00e1le v\u011bt\u0161\u00ed pozornost v\u011bnuje komplexn\u011bj\u0161\u00edmu hodnocen\u00ed krevn\u00edho tlaku, cukru v krvi, rodinn\u00e9 anamn\u00e9zy a jednotliv\u00fdch krevn\u00edch tuk\u016f.<\/span><\/p>\n<p><span dir=\"auto\">Nov\u00e1 studie k tomu p\u0159id\u00e1v\u00e1 dal\u0161\u00ed rozm\u011br: v\u00fdznam z\u00e1n\u011btliv\u00fdch proces\u016f a zm\u011bn c\u00e9vn\u00edch st\u011bn, kter\u00e9 pom\u00e1haj\u00ed vysv\u011btlit rozd\u00edly v rizic\u00edch spojen\u00fdch s jednotliv\u00fdmi lipoproteiny.<\/span><\/p>\n<h2><span dir=\"auto\">Testov\u00e1n\u00ed a prevence: Co z toho vypl\u00fdv\u00e1 pro va\u0161e zdrav\u00ed?<\/span><\/h2>\n<p><span dir=\"auto\">Pokud m\u00e1te v rodin\u011b v\u00fdskyt infarkt\u016f nebo jin\u00fdch srde\u010dn\u011b-c\u00e9vn\u00edch onemocn\u011bn\u00ed, vyplat\u00ed si promluvit s l\u00e9ka\u0159em o dopl\u0148kov\u00fdch krevn\u00edch vy\u0161et\u0159en\u00edch.<\/span><\/p>\n<p><span dir=\"auto\">Zvl\u00e1\u0161tn\u00ed pozornost si zaslou\u017e\u00ed Lp(a), jeho\u017e hladinu se doporu\u010duje zm\u011b\u0159it alespo\u0148 jednou v dosp\u011blosti. Vy\u0161et\u0159en\u00ed apoB je u\u017eite\u010dn\u00e9 zejm\u00e9na tehdy, kdy\u017e b\u011b\u017en\u00e9 hodnoty cholesterolu nemus\u00ed p\u0159esn\u011b vystihovat po\u010det rizikov\u00fdch lipoproteinov\u00fdch \u010d\u00e1stic.<\/span><\/p>\n<p><span dir=\"auto\">D\u016fle\u017eit\u00e1 z\u016fst\u00e1v\u00e1 i ka\u017edodenn\u00ed prevence. Pravideln\u00fd pohyb, kvalitn\u00ed sp\u00e1nek a strava bohat\u00e1 na zeleninu, ovoce, o\u0159echy \u010di mastn\u00e9 ryby podporuj\u00ed zdrav\u00ed c\u00e9v, p\u0159\u00edzniv\u011b ovliv\u0148uj\u00ed krevn\u00ed tuky a pom\u00e1haj\u00ed tlumit chronick\u00e9 z\u00e1n\u011btliv\u00e9 procesy.<\/span><\/p>\n<p><span dir=\"auto\">Stejn\u011b tak d\u016fle\u017eit\u00e9 je udr\u017eovat zdrav\u00fd krevn\u00ed tlak, hladinu cukru v krvi a vyh\u00fdbat se kou\u0159en\u00ed.<\/span><\/p>\n<p><strong><span dir=\"auto\">Dobr\u00fd v\u00fdsledek cholesterolu je p\u0159\u00edznivou zpr\u00e1vou, ale skute\u010dn\u00e9 zdrav\u00ed srdce z\u00e1vis\u00ed i na po\u010dtu rizikov\u00fdch lipoprotein\u016f, z\u00e1n\u011btliv\u00fdch proces\u016f a stavu c\u00e9v.<\/span><\/strong><span dir=\"auto\"> Pr\u00e1v\u011b \u0161ir\u0161\u00ed vy\u0161et\u0159en\u00ed dok\u00e1\u017ee odhalit skryt\u00e1 rizika v\u010das, kdy je\u0161t\u011b existuje prostor pro \u00fa\u010dinnou prevenci.<\/span><\/p>\n<h2><span dir=\"auto\">P\u0159\u00edrodn\u00ed zp\u016fsob l\u00e9\u010dby vysok\u00e9ho cholesterolu<\/span><\/h2>\n<p><span dir=\"auto\">T\u00e9matu cholesterolu, zanesen\u00fdch c\u00e9v a prevence infarkt\u016f a mrtvic se podrobn\u011b v\u011bnujeme v na\u0161\u00ed elektronick\u00e9 knize. V\u00edce informac\u00ed o n\u00ed naleznete <\/span><a href=\"https:\/\/eknihy.shop\/koniec-vysokemu-cholesterolu-a-upchatym-cievam-prirodna-liecba\/\" target=\"_blank\" rel=\"noopener\"><strong><span dir=\"auto\">ZDE<\/span><\/strong><\/a><span dir=\"auto\"> (o \u010desk\u00e9 verzi knihy <\/span><a href=\"https:\/\/eknihy.shop\/konec-vysokemu-cholesterolu-a-ucpanym-cevam-prirodni-lecba\/\" target=\"_blank\" rel=\"noopener\"><strong><span dir=\"auto\">ZDE<\/span><\/strong><\/a><span dir=\"auto\"> ).<\/span><\/p>\n<p><span dir=\"auto\">V knize se dozv\u00edte rizika l\u00e9k\u016f proti cholesterolu (statin\u016f), co d\u011blat, pokud v\u00e1m je l\u00e9ka\u0159 nechce dovolit vysadit, pravdu o n\u00edzkotu\u010dn\u00e9 strav\u011b, p\u0159\u00edznaky ucpan\u00fdch c\u00e9v, p\u0159\u00ed\u010diny ucp\u00e1v\u00e1n\u00ed a zp\u016fsoby jejich vy\u010di\u0161t\u011bn\u00ed, kroky k p\u0159edch\u00e1zen\u00ed infarkt\u016fm a mrtvic\u00edm a mno\u017estv\u00ed dal\u0161\u00edch.<\/span><\/p>\n<p><span dir=\"auto\">Zdroje: <\/span><a href=\"https:\/\/academic.oup.com\/eurheartj\/advance-article\/doi\/10.1093\/eurheartj\/ehag718\/8772973\" target=\"_blank\" rel=\"noopener\"><span dir=\"auto\">academic.oup.com<\/span><\/a><span dir=\"auto\"> , <\/span><a href=\"https:\/\/www.naturalnews.com\/2026-10-21-cholesterol-test-miss-inflammation-linked-heart-risks.html\" target=\"_blank\" rel=\"noopener\"><span dir=\"auto\">naturalnews.com<\/span><\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>M\u00e1te cholesterol v norm\u011b a mysl\u00edte si, \u017ee va\u0161e srdce je v bezpe\u010d\u00ed? Nov\u00fd v\u00fdzkum&#8230;<\/p>\n","protected":false},"author":2,"featured_media":119358,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[6252,110,21],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/119357"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=119357"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/119357\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/119358"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=119357"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=119357"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=119357"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}