{"id":117880,"date":"2026-10-09T00:21:57","date_gmt":"2026-10-08T22:21:57","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=117880"},"modified":"2026-10-08T13:41:16","modified_gmt":"2026-10-08T11:41:16","slug":"zatimco-se-titulky-o-moru-vraceji-vice-nez-21-kandidatu-na-vakcinu-je-jiz-v-plnem-proudu-ve-vyvoji","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2026\/10\/09\/zatimco-se-titulky-o-moru-vraceji-vice-nez-21-kandidatu-na-vakcinu-je-jiz-v-plnem-proudu-ve-vyvoji\/","title":{"rendered":"Zat\u00edmco se titulky o moru vracej\u00ed: V\u00edce ne\u017e 21 kandid\u00e1t\u016f na vakc\u00ednu je ji\u017e v pln\u00e9m proudu ve v\u00fdvoji"},"content":{"rendered":"
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Zat\u00edmco nevysv\u011btliteln\u00e1 smrt mlad\u00e9ho zam\u011bstnance protimorov\u00e9ho \u00fastavu v Irkutsku na Sibi\u0159i se dost\u00e1v\u00e1 na tituln\u00ed str\u00e1nky mezin\u00e1rodn\u00edch m\u00e9di\u00ed, do centra pozornosti se dost\u00e1v\u00e1 dal\u0161\u00ed aspekt: <\/span>\u200b\u200bvl\u00e1dy, v\u00fdzkumn\u00e9 instituce a vojensk\u00e9 programy biologick\u00e9 obrany ji\u017e l\u00e9ta pracuj\u00ed na nov\u00e9 generaci vakc\u00edn proti moru.<\/span><\/strong> Pat\u0159\u00ed mezi n\u011b mRNA, samoamplifikuj\u00edc\u00ed se RNA, DNA a vektorov\u00e9 vakc\u00edny, stejn\u011b jako klasick\u00e9 proteinov\u00e9 a \u017eiv\u00e9 vakc\u00edny.<\/span><\/p>\n

Epidemiolog <\/span>Nicolas Hulscher<\/span><\/strong> z McCulloughovy nadace se t\u00edmto v\u00fdvojem zab\u00fdv\u00e1 v ned\u00e1vn\u00e9m \u010dl\u00e1nku a s ohledem na nov\u00e9 titulky o moru se pt\u00e1: Pro\u010d se tolik investovalo do nov\u00fdch vakcina\u010dn\u00edch platforem proti nemoci, kter\u00e1 je do zna\u010dn\u00e9 m\u00edry vn\u00edm\u00e1na jako p\u0159e\u017eitek minul\u00fdch stalet\u00ed?<\/span><\/p>\n

V\u00edce ne\u017e 21 kandid\u00e1t\u016f \u2013 dokonce p\u0159ed Irkutskem<\/span><\/h2>\n

Toto \u010d\u00edslo nen\u00ed pouze Hulscherovo. V\u011bdeck\u00fd <\/span>p\u0159ehled<\/span><\/a> glob\u00e1ln\u00edho v\u00fdzkumu vakc\u00edn proti moru publikovan\u00fd v roce 2024 uv\u00e1d\u00ed <\/span>v\u00edce ne\u017e 21 kandid\u00e1t\u016f na vakc\u00edny pouze v preklinick\u00e9 f\u00e1zi<\/span><\/strong> . Krom\u011b toho existuj\u00ed kandid\u00e1ti, kte\u0159\u00ed ji\u017e pro\u0161li nebo v sou\u010dasn\u00e9 dob\u011b proch\u00e1zej\u00ed klinick\u00fdmi studiemi na lidech. Technologie sahaj\u00ed od podjednotkov\u00fdch a \u017eiv\u00fdch vakc\u00edn a\u017e po bakteri\u00e1ln\u00ed a virov\u00e9 vektory, stejn\u011b jako DNA a mRNA.<\/span><\/p>\n

\"Zat\u00edmco<\/figure>\n

Obzvl\u00e1\u0161t\u011b pozoruhodn\u00e1 je \u0161k\u00e1la z\u00fa\u010dastn\u011bn\u00fdch zem\u00ed.<\/span><\/p>\n

Izrael<\/span><\/strong> pracuje na vakc\u00edn\u00e1ch na b\u00e1zi mRNA lipidov\u00fdch nano\u010d\u00e1stic. V\u00fdzkumn\u00edci z Tel Avivsk\u00e9 univerzity a Izraelsk\u00e9ho institutu pro biologick\u00fd v\u00fdzkum publikovali v roce 2023 vakc\u00ednu mRNA na b\u00e1zi F1; v roce 2025 n\u00e1sledovala bivalentn\u00ed formulace mRNA F1\/LcrV proti plicn\u00edmu moru. Podle Hulschera jsou ob\u011b st\u00e1le v preklinick\u00e9 f\u00e1zi.<\/span><\/p>\n

Technologie RNA se pou\u017e\u00edv\u00e1 i ve <\/span>Velk\u00e9 Brit\u00e1nii . V\u00fdzkumn\u00edci, v\u010detn\u011b t\u011bch z Imperial College London a britsk\u00e9 obrann\u00e9 laborato\u0159e Dstl Porton Down, vyvinuli samoamplifikuj\u00edc\u00ed se RNA vakc\u00ednu \u2013 tzv. saRNA \u2013 proti <\/span><\/strong>Yersinia pestis<\/span><\/em> .<\/span><\/p>\n

Americk\u00e1 arm\u00e1da financuje vakc\u00ednu proti moru<\/span><\/h2>\n

Je\u0161t\u011b pozoruhodn\u011bj\u0161\u00ed je zapojen\u00ed americk\u00e9ho <\/span>ministerstva obrany<\/span><\/strong> .<\/span><\/p>\n

Vakc\u00edna <\/span>rF1V-1018 je <\/span><\/strong>vyv\u00edjena<\/span><\/a> spole\u010dn\u011b se spole\u010dnost\u00ed Dynavax . Prezentace pro WHO v\u00fdslovn\u011b potvrzuje spolupr\u00e1ci s americk\u00fdm ministerstvem obrany. Vakc\u00edna ji\u017e byla testov\u00e1na ve f\u00e1zi 2 klinick\u00fdch studi\u00ed na lidech. C\u00edlem je rychlej\u0161\u00ed imunizace dv\u011bma o\u010dkov\u00e1n\u00edmi b\u011bhem jednoho m\u011bs\u00edce nam\u00edsto t\u0159\u00ed o\u010dkov\u00e1n\u00ed b\u011bhem \u0161esti m\u011bs\u00edc\u016f.<\/span><\/p>\n

Vojensk\u00e9 <\/span>pozad\u00ed<\/span><\/a> je jasn\u00e9: P\u0159\u00edpravek je vyv\u00edjen mimo jin\u00e9 k ochran\u011b p\u0159ed <\/span>plicn\u00edm morem po expozici aerosolu s <\/span>Yersinia pestis<\/span><\/em><\/strong> .<\/span><\/p>\n

A\u017e <\/span>17. srpna 2026<\/span><\/strong> vakc\u00edna z\u00edskala od americk\u00e9ho \u00da\u0159adu pro kontrolu potravin a l\u00e9\u010div (FDA) ozna\u010den\u00ed \u201eOrphan Drug Design\u201c pro prevenci moru. Toto ozna\u010den\u00ed v\u0161ak v\u00fdslovn\u011b nep\u0159edstavuje <\/span>schv\u00e1len\u00ed<\/span><\/a> jako vakc\u00edny.<\/span><\/p>\n

Oxford, \u010c\u00edna a Rusko<\/span><\/h2>\n

Oxford<\/span><\/strong> je tak\u00e9 zapojen. F\u00e1ze 1 klinick\u00fdch studi\u00ed vakc\u00edny proti moru zalo\u017een\u00e9 na <\/span>platform\u011b ChAdOx1<\/span><\/strong> \u2013 stejn\u00e9 adenovirov\u00e9 technologii, kter\u00e1 se pou\u017e\u00edv\u00e1 ve vakc\u00edn\u011b proti covidu od Oxfordu\/AstraZeneca \u2013 tam za\u010dala ji\u017e v roce 2021.<\/span><\/p>\n

\u010c\u00edna tak\u00e9 zah\u00e1jila klinick\u00e9 studie s vakc\u00ednou proti moru F1+ rV. Rusko zase v roce 2024 ud\u011blilo registraci nov\u00e9 molekul\u00e1rn\u00ed vakc\u00edn\u011b proti moru obsahuj\u00edc\u00ed rekombinantn\u00ed antigeny F1 a rV.<\/span><\/p>\n

A najednou se mor op\u011bt dost\u00e1v\u00e1 na tituln\u00ed str\u00e1nky novin.<\/span><\/h2>\n

V t\u00e9to souvislosti se aktu\u00e1ln\u00edmu p\u0159\u00edpadu v Irkutsku v\u011bnuje zvl\u00e1\u0161tn\u00ed pozornost. Osmadvacetilet\u00fd v\u011bdec z m\u00edstn\u00edho protimorov\u00e9ho \u00fastavu zem\u0159el po rychle se rozv\u00edjej\u00edc\u00edm z\u00e1palu plic nezn\u00e1m\u00e9ho p\u016fvodu. Kontaktn\u00ed osoby byly izolov\u00e1ny nebo monitorov\u00e1ny a n\u011bkolik zdravotnick\u00fdch za\u0159\u00edzen\u00ed bylo um\u00edst\u011bno do karant\u00e9ny.<\/span><\/p>\n

Rusk\u00e9 \u00fa\u0159ady dosud uvedly <\/span>, \u017ee neexistuje \u017e\u00e1dn\u00e9 potvrzen\u00e9 ohnisko moru ani prok\u00e1zan\u00e1 laboratorn\u00ed nehoda<\/span><\/strong> . Ani p\u0159\u00edb\u011bh koluj\u00edc\u00ed na internetu o rozbit\u00e9 n\u00e1dob\u011b s morov\u00fdmi patogeny nebyl potvrzen. S\u00e1m Hulscher na toto ofici\u00e1ln\u00ed prohl\u00e1\u0161en\u00ed poukazuje.<\/span><\/p>\n

To znamen\u00e1, \u017ee je t\u0159eba rozli\u0161ovat mezi dv\u011bma v\u011bcmi: <\/span>Mezin\u00e1rodn\u00ed programy o\u010dkov\u00e1n\u00ed proti moru prokazateln\u011b existovaly dlouho p\u0159ed incidentem v Irkutsku. Souvislost mezi t\u011bmito programy a \u00famrt\u00edm na Sibi\u0159i v\u0161ak nebyla prok\u00e1z\u00e1na.<\/span><\/strong><\/p>\n

Na\u010dasov\u00e1n\u00ed je nicm\u00e9n\u011b pozoruhodn\u00e9: Zat\u00edmco ve\u0159ejnost n\u00e1hle op\u011bt mluv\u00ed o moru, pohled do z\u00e1kulis\u00ed ukazuje, \u017ee tato nemoc nebyla v mezin\u00e1rodn\u00edm v\u00fdzkumu biologick\u00e9 obrany v \u017e\u00e1dn\u00e9m p\u0159\u00edpad\u011b zapomenuta.<\/span><\/p>\n<\/div>\n<\/div>\n

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Zdroj<\/span><\/a><\/span><\/h3>\n

 <\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Zat\u00edmco nevysv\u011btliteln\u00e1 smrt mlad\u00e9ho zam\u011bstnance protimorov\u00e9ho \u00fastavu v Irkutsku na Sibi\u0159i se dost\u00e1v\u00e1 na tituln\u00ed…<\/p>\n","protected":false},"author":2,"featured_media":105122,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[9936,651,2009],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/117880"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=117880"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/117880\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/105122"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=117880"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=117880"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=117880"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}