{"id":117161,"date":"2026-10-01T00:22:36","date_gmt":"2026-09-30T22:22:36","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=117161"},"modified":"2026-09-30T08:59:39","modified_gmt":"2026-09-30T06:59:39","slug":"zasadni-lekarsky-posun-hlavnim-prediktorem-srdecnich-onemocneni-jiz-neni-cholesterol-ale-zanet","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2026\/10\/01\/zasadni-lekarsky-posun-hlavnim-prediktorem-srdecnich-onemocneni-jiz-neni-cholesterol-ale-zanet\/","title":{"rendered":"Z\u00e1sadn\u00ed l\u00e9ka\u0159sk\u00fd posun: Hlavn\u00edm prediktorem srde\u010dn\u00edch onemocn\u011bn\u00ed ji\u017e nen\u00ed cholesterol, ale z\u00e1n\u011bt"},"content":{"rendered":"
<\/div>\n

V\u00e1lka proti srde\u010dn\u00edm chorob\u00e1m se cel\u00e1 desetilet\u00ed odehr\u00e1vala zejm\u00e9na na boji\u0161ti cholesterolu.<\/span><\/strong><\/p>\n

L\u00e9ka\u0159i varovali p\u0159ed mastn\u00fdmi j\u00eddly, p\u0159edepisovali statiny ke sn\u00ed\u017een\u00ed \u201e\u0161patn\u00e9ho\u201c LDL cholesterolu a lipidov\u00fd profil pat\u0159il mezi hlavn\u00ed ukazatele kardiovaskul\u00e1rn\u00edho rizika. Tato \u00e9ra pr\u00e1v\u011b skon\u010dila.<\/span><\/p>\n

Americk\u00e1 kardiologick\u00e1 akademie (American College of Cardiology<\/span><\/em> \u2013 ACC) toti\u017e v nov\u00e9m v\u011bdeck\u00e9m stanovisku v\u00fdrazn\u011b posunula chronick\u00fd z\u00e1n\u011bt do centra pozornosti. Ozna\u010duje jej za d\u016fle\u017eit\u00fd a nez\u00e1visl\u00fd prediktor infarktu a mozkov\u00e9 p\u0159\u00edhody.<\/span><\/p>\n

U lid\u00ed s ji\u017e rozvinut\u00fdm kardiovaskul\u00e1rn\u00edm onemocn\u011bn\u00edm p\u0159itom m\u016f\u017ee b\u00fdt z\u00e1n\u011btliv\u00fd marker hsCRP p\u0159inejmen\u0161\u00edm stejn\u011b siln\u00fdm prediktorem dal\u0161\u00edch p\u0159\u00edhod a \u00famrt\u00ed jako LDL cholesterol.<\/span><\/p>\n

Jedn\u00e1 se o z\u00e1sadn\u00ed zm\u011bnu pohledu na prevenci. ACC doporu\u010duje m\u011b\u0159it hsCRP vedle tradi\u010dn\u00edch test\u016f cholesterolu v prim\u00e1rn\u00ed i sekund\u00e1rn\u00ed prevenci. Jednoduch\u00fd krevn\u00ed test tak odhaluje dal\u0161\u00ed vrstvu rizika, kter\u00e1 dosud z\u016fst\u00e1vala nepov\u0161imnuta.<\/span><\/p>\n

A nejde o okrajov\u00fd probl\u00e9m. P\u0159ibli\u017en\u011b 52 % dosp\u011bl\u00fdch Ameri\u010dan\u016f m\u00e1 hsCRP nejm\u00e9n\u011b 2 mg\/l, tedy hodnotu spojenou se zv\u00fd\u0161en\u00fdm z\u00e1n\u011btliv\u00fdm rizikem.<\/span><\/p>\n

Z\u00e1n\u011bt se dost\u00e1v\u00e1 do centra pozornosti<\/span><\/h2>\n

Test hsCRP nen\u00ed novinkou. M\u011bn\u00ed se v\u0161ak jeho v\u00fdznam.<\/span><\/p>\n

ACC jej dnes doporu\u010duje sledovat spolu s cholesterolem jako marker chronick\u00e9ho syst\u00e9mov\u00e9ho z\u00e1n\u011btu n\u00edzk\u00e9ho stupn\u011b. Jak uv\u00e1d\u00ed ve sv\u00e9m stanovisku: \u201eZ\u00e1n\u011bt hraje \u00fast\u0159edn\u00ed roli v patogenezi ateroskler\u00f3zy a kardiovaskul\u00e1rn\u00edch onemocn\u011bn\u00ed.\u201c<\/span><\/p>\n

C-reaktivn\u00ed protein vznik\u00e1 p\u0159ev\u00e1\u017en\u011b v j\u00e1trech a jeho hladina stoup\u00e1 p\u0159i aktivaci z\u00e1n\u011btliv\u00fdch proces\u016f. P\u0159i hodnocen\u00ed kardiovaskul\u00e1rn\u00edho rizika se tradi\u010dn\u011b za n\u00edzkou pova\u017euje hodnota hsCRP pod 1 mg\/l, za st\u0159edn\u00ed 1 a\u017e 3 mg\/la za vysokou nad 3 mg\/l. Hodnota od 2 mg\/l se z\u00e1rove\u0148 \u010dasto pou\u017e\u00edv\u00e1 jako hranice zv\u00fd\u0161en\u00e9ho rezidu\u00e1ln\u00edho z\u00e1n\u011btliv\u00e9ho rizika.<\/span><\/p>\n

V\u00fdzkum ukazuje, \u017ee hsCRP dok\u00e1\u017ee p\u0159edpov\u00eddat budouc\u00ed riziko ischemick\u00e9 choroby srde\u010dn\u00ed a up\u0159esnit odhad kardiovaskul\u00e1rn\u00edho rizika.<\/span><\/p>\n

Pro\u010d je tak d\u016fle\u017eit\u00fd?<\/span><\/p>\n

Proto\u017ee z\u00e1n\u011bt doprov\u00e1z\u00ed ateroskler\u00f3zu prakticky od za\u010d\u00e1tku do konce. Pod\u00edl\u00ed se na poru\u0161e funkce c\u00e9vn\u00ed v\u00fdstelky, reakci imunitn\u00edho syst\u00e9mu na \u010d\u00e1stice zachycen\u00e9 ve st\u011bn\u011b tepny, r\u016fstu plaku i na jeho destabilizaci a prasknut\u00ed, kter\u00e9 m\u016f\u017ee vy\u00fastit v infarkt nebo mozkovou p\u0159\u00edhodu.<\/span><\/p>\n

Zjednodu\u0161en\u011b: cholesterol je sou\u010d\u00e1st\u00ed materi\u00e1lu, ze kter\u00e9ho aterosklerotick\u00fd plak vznik\u00e1, ale z\u00e1n\u011bt v\u00fdrazn\u011b ovliv\u0148uje, co se s n\u00edm d\u00e1le d\u011bje.<\/span><\/p>\n

I proto ACC upozor\u0148uje, \u017ee u pacient\u016f s ji\u017e rozvinut\u00fdm aterosklerotick\u00fdm kardiovaskul\u00e1rn\u00edm onemocn\u011bn\u00edm je zv\u00fd\u0161en\u00fd hsCRP p\u0159inejmen\u0161\u00edm stejn\u011b siln\u00fdm prediktorem budouc\u00edch p\u0159\u00edhod a \u00famrt\u00ed jako LDL cholesterol.<\/span><\/p>\n

Riziko, kter\u00e9 dok\u00e1\u017eete ovlivnit<\/span><\/h2>\n

Nejd\u016fle\u017eit\u011bj\u0161\u00ed zpr\u00e1va zn\u00ed: z\u00e1n\u011btliv\u00e9 riziko nen\u00ed nem\u011bnn\u00e9.<\/span><\/p>\n

\u201ehsCRP je modifikovateln\u00fd a \u010dasto jej lze sn\u00ed\u017eit prost\u0159ednictv\u00edm behavior\u00e1ln\u00edch a \u017eivotn\u00edch intervenc\u00ed,\u201c<\/span><\/em> uv\u00e1d\u00ed v\u011bdeck\u00e9 stanovisko ACC.<\/span><\/p>\n

Z\u00e1kladn\u00ed strategie jsou zn\u00e1m\u00e9: st\u0159edomo\u0159sk\u00e1 strava, pravideln\u00fd pohyb, nekou\u0159en\u00ed a udr\u017eov\u00e1n\u00ed zdrav\u00e9 t\u011blesn\u00e9 hmotnosti. Nejde jen o obecn\u00e9 rady \u2013 v\u0161echny tyto faktory ovliv\u0148uj\u00ed tak\u00e9 z\u00e1n\u011btliv\u00e9 procesy v organismu.<\/span><\/p>\n

Metaanal\u00fdzy nazna\u010duj\u00ed, \u017ee st\u0159edomo\u0159sk\u00fd zp\u016fsob stravov\u00e1n\u00ed dok\u00e1\u017ee m\u011b\u0159iteln\u011b sni\u017eovat hsCRP. ACC upozor\u0148uje tak\u00e9 na p\u0159\u00ednos stravy typu DASH (strava navr\u017een\u00e1 pro sn\u00ed\u017een\u00ed krevn\u00edho tlaku) a j\u00eddeln\u00ed\u010dku bohat\u00e9ho na vl\u00e1kninu.<\/span><\/p>\n

Zaj\u00edmav\u00e9 v\u00fdsledky p\u0159inesly i studie rostlinn\u00fdch j\u00eddeln\u00ed\u010dk\u016f kombinuj\u00edc\u00edch <\/span>visk\u00f3zn\u00ed vl\u00e1kninu, rostlinn\u00e9 steroly, o\u0159echy a rostlinn\u00e9 b\u00edlkoviny<\/span><\/strong> . V jedn\u00e9 men\u0161\u00ed studii se jejich vliv na n\u011bkter\u00e9 rizikov\u00e9 ukazatele dostal na \u00farove\u0148 srovnatelnou se statinovou l\u00e9\u010dbou.<\/span><\/p>\n

S ni\u017e\u0161\u00edmi z\u00e1n\u011btliv\u00fdmi markery se spojuj\u00ed i <\/span>\u200b\u200bbobulov\u00e9 ovoce, olivov\u00fd olej, o\u0159echy \u010di semena<\/span><\/strong> .<\/span><\/p>\n

V\u00fdznam m\u00e1 tak\u00e9 <\/span>t\u011blesn\u00e1 hmotnost<\/span><\/strong> . Systematick\u00e9 p\u0159ehledy ukazuj\u00ed, \u017ee se sni\u017eov\u00e1n\u00edm hmotnosti kles\u00e1 i CRP. Podobn\u011b p\u016fsob\u00ed pravideln\u00e1 aerobn\u00ed aktivita.<\/span><\/p>\n

Z\u00e1n\u011bt tedy nen\u00ed jen dal\u0161\u00ed \u010d\u00edslo v laboratorn\u00edm v\u00fdsledku. Do zna\u010dn\u00e9 m\u00edry odr\u00e1\u017e\u00ed tak\u00e9 to, co se v organismu d\u011bje ka\u017ed\u00fd den.<\/span><\/p>\n

Prevence srde\u010dn\u00edch chorob se t\u00edm z\u00e1sadn\u011b m\u011bn\u00ed<\/span><\/h2>\n

Jedn\u00e1 se o p\u0159eps\u00e1n\u00ed za\u017eit\u00e9ho zp\u016fsobu uva\u017eov\u00e1n\u00ed o kardiovaskul\u00e1rn\u00ed prevenci.<\/span><\/p>\n

Diskuse se u\u017e nem\u016f\u017ee to\u010dit jen kolem LDL cholesterolu. Do obrazu vstupuje i z\u00e1n\u011bt, po\u010det aterogenn\u00edch \u010d\u00e1stic m\u011b\u0159en\u00fd nap\u0159\u00edklad prost\u0159ednictv\u00edm apolipoproteinu B a geneticky v\u00fdrazn\u011b podm\u00edn\u011bn\u00fd lipoprotein(a).<\/span><\/p>\n

Ka\u017ed\u00fd z t\u011bchto ukazatel\u016f zachycuje jinou \u010d\u00e1st rizika. \u010clov\u011bk tak m\u016f\u017ee m\u00edt relativn\u011b p\u0159\u00edzniv\u00fd cholesterol, ale st\u00e1le n\u00e9st zv\u00fd\u0161en\u00e9 z\u00e1n\u011btliv\u00e9 riziko – nebo naopak.<\/span><\/p>\n

Pr\u00e1v\u011b proto d\u00e1v\u00e1 kombinace v\u00edce ukazatel\u016f \u0161ir\u0161\u00ed obraz ne\u017e samotn\u00fd klasick\u00fd lipidov\u00fd profil. ACC proto doporu\u010duje za\u0159adit hsCRP do hodnocen\u00ed kardiovaskul\u00e1rn\u00edho rizika ao jeho vy\u0161et\u0159en\u00ed se lze poradit s l\u00e9ka\u0159em.<\/span><\/p>\n

Velk\u00fdm odhalen\u00edm posledn\u00edch let je, \u017ee o tom, zda aterosklerotick\u00fd plak z\u016fstane relativn\u011b stabiln\u00ed nebo se z n\u011bj stane \u010dasovan\u00e1 bomba, nerozhoduje jen mno\u017estv\u00ed cholesterolu. V\u00fdznamnou roli hraje i obrann\u00fd syst\u00e9m vlastn\u00edho t\u011bla a z\u00e1n\u011btliv\u00e1 reakce, kterou vytv\u00e1\u0159\u00ed.<\/span><\/p>\n

Desetilet\u00ed trvaj\u00edc\u00ed zam\u011b\u0159en\u00ed na cholesterol bylo ne\u00fapln\u00e9. Skute\u010dn\u00e1 prevence dnes znamen\u00e1 d\u00edvat se hloub\u011bji: nejen na cholesterol, ale tak\u00e9 na z\u00e1n\u011bt, metabolick\u00e9 zdrav\u00ed, pohyb, t\u011blesnou hmotnost a dal\u0161\u00ed faktory, kter\u00e9 rozhoduj\u00ed o tom, co se v na\u0161ich c\u00e9v\u00e1ch skute\u010dn\u011b d\u011bje.<\/span><\/p>\n

A pr\u00e1v\u011b zde se skr\u00fdv\u00e1 nejd\u016fle\u017eit\u011bj\u0161\u00ed zpr\u00e1va cel\u00e9ho posunu: vnit\u0159n\u00ed z\u00e1n\u011bt nen\u00ed jen n\u011bco, co si nech\u00e1te zm\u011b\u0159it, ale rizikov\u00fd faktor, kter\u00fd dok\u00e1\u017eete sv\u00fdmi ka\u017edodenn\u00edmi rozhodnut\u00edmi v\u00fdrazn\u011b ovlivnit.<\/span><\/p>\n

P\u0159\u00edrodn\u00ed zp\u016fsob ochrany srdce a c\u00e9v<\/span><\/h2>\n

T\u00e9matu zanesen\u00fdch c\u00e9v, cholesterolu a prevence infarkt\u016f a mrtvic se podrobn\u011b v\u011bnujeme v na\u0161\u00ed elektronick\u00e9 knize. V\u00edce informac\u00ed o n\u00ed naleznete <\/span>ZDE<\/span><\/strong><\/a> (o \u010desk\u00e9 verzi knihy <\/span>ZDE<\/span><\/strong><\/a> ).<\/span><\/p>\n

V knize se dozv\u00edte rizika l\u00e9k\u016f proti cholesterolu (statin\u016f), co d\u011blat, pokud v\u00e1m je l\u00e9ka\u0159 nechce dovolit vysadit, pravdu o n\u00edzkotu\u010dn\u00e9 strav\u011b, p\u0159\u00edznaky ucpan\u00fdch c\u00e9v, p\u0159\u00ed\u010diny jejich ucp\u00e1v\u00e1n\u00ed a zp\u016fsoby na vy\u010di\u0161t\u011bn\u00ed c\u00e9v, kroky k p\u0159edch\u00e1zen\u00ed infarkt\u016fm a mrtvic\u00edm.<\/span><\/p>\n

Autor: Cassie B., Zdroj: <\/span>naturalnews.com<\/span><\/a><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

V\u00e1lka proti srde\u010dn\u00edm chorob\u00e1m se cel\u00e1 desetilet\u00ed odehr\u00e1vala zejm\u00e9na na boji\u0161ti cholesterolu. L\u00e9ka\u0159i varovali p\u0159ed…<\/p>\n","protected":false},"author":2,"featured_media":117162,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[6252,1556,11671,21],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/117161"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=117161"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/117161\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/117162"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=117161"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=117161"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=117161"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}