{"id":116750,"date":"2026-09-26T00:12:38","date_gmt":"2026-09-25T22:12:38","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=116750"},"modified":"2026-09-25T11:40:23","modified_gmt":"2026-09-25T09:40:23","slug":"profesor-sucharit-bhakdi-predstavuje-novou-teorii-o-onemocnenich-po-ockovani-mrna","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2026\/09\/26\/profesor-sucharit-bhakdi-predstavuje-novou-teorii-o-onemocnenich-po-ockovani-mrna\/","title":{"rendered":"Profesor Sucharit Bhakdi p\u0159edstavuje novou teorii o onemocn\u011bn\u00edch po o\u010dkov\u00e1n\u00ed mRNA"},"content":{"rendered":"<div id=\"fb-root\"><\/div>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Na oslav\u00e1ch 20. v\u00fdro\u010d\u00ed UK Column profesor Sucharit Bhakdi poprv\u00e9 ve\u0159ejn\u011b p\u0159edstavil hypot\u00e9zu, kter\u00e1 nazna\u010duje, \u017ee neurologick\u00e9 symptomy po o\u010dkov\u00e1n\u00ed mRNA vznikaj\u00ed v d\u016fsledku samovoln\u011b se opakuj\u00edc\u00edho procesu demyelinizace. D\u016fchodce, mikrobiolog a b\u00fdval\u00fd \u0159editel \u00dastavu l\u00e9ka\u0159sk\u00e9 mikrobiologie na Univerzit\u011b v Mohu\u010di, si pro premi\u00e9ru z\u00e1m\u011brn\u011b vybral toto publikum. Zd\u016fraznil, \u017ee se jedn\u00e1 o pracovn\u00ed hypot\u00e9zu, dosud neprok\u00e1zanou, zalo\u017eenou na v\u011bdeck\u00fdch \u00favah\u00e1ch, a \u017ee vyz\u00fdv\u00e1 k dal\u0161\u00edmu testov\u00e1n\u00ed.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">N\u00e1sledovala nikoli obvykl\u00e1 kritika vakc\u00edn, ale pokus vysv\u011btlit spole\u010dn\u00fd vzorec, kter\u00fd se skr\u00fdv\u00e1 za velmi odli\u0161n\u00fdmi p\u0159\u00edznaky: ztr\u00e1ta kontroly nad pohyby, my\u0161lenkami, vzpom\u00ednkami a osobnost\u00ed.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">N\u011bmeck\u00fd dabing s um\u011blou inteligenc\u00ed lze aktivovat v nastaven\u00ed YouTube.<\/span><\/p>\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\n<div class=\"wp-block-embed__wrapper\"><iframe loading=\"lazy\" title=\"Profesor Sucharit Bhakdi odhaluje novou teorii o onemocn\u011bn\u00ed po o\u010dkov\u00e1n\u00ed mRNA\" src=\"https:\/\/www.youtube.com\/embed\/pUY99pbeXao?feature=oembed\" width=\"800\" height=\"450\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\" data-mce-fragment=\"1\"><\/iframe><\/div>\n<\/figure>\n<h2 class=\"wp-block-heading\"><span dir=\"auto\">Nov\u00ed spojenci a dv\u011b knihy<\/span><\/h2>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Fale\u0161n\u00ed p\u0159\u00e1tel\u00e9 zmizeli a na jejich m\u00edsto p\u0159i\u0161li opravdov\u00ed p\u0159\u00e1tel\u00e9 a \u201eskv\u011bl\u00ed lid\u00e9\u201c. Doporu\u010dil nejnov\u011bj\u0161\u00ed knihu od autora jm\u00e9nem Sharaf a tak\u00e9 <\/span><strong><span dir=\"auto\">\u201eVakc\u00ednov\u00e1 mafie\u201c od Helmuta Sterze<\/span><\/strong><span dir=\"auto\"> .<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Sterz byl d\u0159\u00edve hlavn\u00edm toxikologem spole\u010dnosti Pfizer pro Evropu a zn\u00e1 regula\u010dn\u00ed po\u017eadavky l\u00e9pe ne\u017e t\u00e9m\u011b\u0159 kdokoli jin\u00fd. Kniha byla p\u016fvodn\u011b vyd\u00e1na v n\u011bm\u010din\u011b a nyn\u00ed je k dispozici v angli\u010dtin\u011b u nakladatelstv\u00ed Skyhorse.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Bhakdi spolu se Sterzem sestavili kompendium. Jeho n\u00e1zev v podstat\u011b zn\u00ed, <\/span><strong><span dir=\"auto\">\u017ee mRNA o\u010dkov\u00e1n\u00ed je nejv\u011bt\u0161\u00edm organizovan\u00fdm l\u00e9ka\u0159sk\u00fdm zlo\u010dinem v historii<\/span><\/strong><span dir=\"auto\"> . Jmenuje vin\u00edky a poskytuje podklady pro pr\u00e1vn\u00ed kroky. N\u011bmeck\u00e1 verze je na trhu asi \u0161est m\u011bs\u00edc\u016f. Skyhorse poslal anglick\u00e9 vyd\u00e1n\u00ed k tisku deset dn\u00ed p\u0159ed p\u0159edn\u00e1\u0161kou.<\/span><\/p>\n<h2 class=\"wp-block-heading\"><span dir=\"auto\">Od infarktu k demyelinizaci<\/span><\/h2>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">T\u0159et\u00ed a podle Bhakdiho nejlep\u0161\u00ed \u201en\u00e1vrat\u201c je nov\u00fdm vysv\u011btlen\u00edm utrpen\u00ed po o\u010dkov\u00e1n\u00ed. Kdy\u017e se koronavirus \u201eznovu propadl do pekla\u201c, lid\u00e9 z\u016fstali posti\u017een\u00ed, zbaveni prost\u0159edk\u016f k p\u0159e\u017eit\u00ed. \u017d\u00e1dn\u00e1 v\u00e1lka si nikdy nevy\u017e\u00e1dala tolik \u017eivot\u016f.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Prvn\u00ed odpov\u011bdi \u2013 srde\u010dn\u00ed choroby, trombotick\u00e9 p\u0159\u00edhody, autoimunitn\u00ed onemocn\u011bn\u00ed, rakovinu \u2013 o\u010dek\u00e1val od sam\u00e9ho za\u010d\u00e1tku. V l\u00e9t\u011b 2026 si v\u0161ak v\u0161iml n\u011b\u010deho \u201enekone\u010dn\u011b temn\u011bj\u0161\u00edho\u201c: mnoho lid\u00ed jako by ztr\u00e1celo kontrolu nad sv\u00fdm mozkem, pohyby, my\u0161lenkami, vzpom\u00ednkami a osobnost\u00ed.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">V \u010dervenci si uv\u011bdomil spole\u010dn\u00e9ho jmenovatele: <\/span><strong><span dir=\"auto\">demyeliniza\u010dn\u00ed onemocn\u011bn\u00ed<\/span><\/strong><span dir=\"auto\"> .<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Centr\u00e1ln\u00ed nervov\u00fd syst\u00e9m funguje prost\u0159ednictv\u00edm neuron\u016f, kter\u00e9 p\u0159en\u00e1\u0161ej\u00ed elektrick\u00e9 sign\u00e1ly axony. Elektrick\u00e9 impulsy nemohou proch\u00e1zet vodou, a proto jsou nervy obaleny myelinem. Tyto vodoodpudiv\u00e9 obaly jsou produkov\u00e1ny oligodendrocyty \u2013 bu\u0148kami, kter\u00e9 se nach\u00e1zej\u00ed v obrovsk\u00e9m mno\u017estv\u00ed pod\u00e9l nervov\u00fdch vl\u00e1ken a obaluj\u00ed je.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Kdy\u017e se myelinov\u00e9 pochvy rozpadnou, nervy p\u0159estanou fungovat. Podle Bhakdiho se p\u0159esn\u011b tohle d\u011bje milion\u016fm lid\u00ed v\u0161ech v\u011bkov\u00fdch kategori\u00ed. P\u0159\u00edznaky odpov\u00eddaj\u00ed klasick\u00fdm demyeliniza\u010dn\u00edm onemocn\u011bn\u00edm: <\/span><strong><span dir=\"auto\">roztrou\u0161en\u00e9 skler\u00f3ze, Alzheimerov\u011b chorob\u011b, Guillain-Barr\u00e9ovu syndromu, transverz\u00e1ln\u00ed myelitid\u011b, Parkinsonov\u011b chorob\u011b a autismu.<\/span><\/strong><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Pro\u010d oligodendrocyty odum\u00edraj\u00ed? Je zn\u00e1mo, \u017ee u Alzheimerovy choroby se ucp\u00e1vaj\u00ed nejmen\u0161\u00ed c\u00e9vy v \u010deln\u00edm laloku (\u201eonemocn\u011bn\u00ed mal\u00fdch c\u00e9v\u201c). Viry a traumata \u2013 nap\u0159\u00edklad u boxer\u016f \u2013 mohou tak\u00e9 zp\u016fsobit lok\u00e1ln\u00ed po\u0161kozen\u00ed.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Skute\u010dnou z\u00e1hadou modern\u00ed medic\u00edny v\u0161ak je, pro\u010d demyelinizace, jakmile jednou za\u010dne, sama od sebe nezastav\u00ed. Standardn\u00ed odpov\u011b\u010f zn\u00ed: imunitn\u00ed syst\u00e9m \u0159\u00e1d\u00ed. Terapie se skl\u00e1d\u00e1 prim\u00e1rn\u011b z imunosupresiv, po\u010d\u00ednaje kortizonem \u2013 bez v\u00fdznamn\u00e9ho \u00fasp\u011bchu.<\/span><\/p>\n<h2 class=\"wp-block-heading\"><span dir=\"auto\">Kask\u00e1da: ciz\u00ed protein, c\u00e9vn\u00ed st\u011bna, komplement<\/span><\/h2>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Bhakdi zopakoval sv\u00e9 d\u0159\u00edv\u011bj\u0161\u00ed varov\u00e1n\u00ed: mRNA vstupuje do bun\u011bk, se kter\u00fdmi p\u0159ijde do kontaktu \u2013 nejprve do c\u00e9vn\u00edch st\u011bn, zejm\u00e9na v mal\u00fdch c\u00e9v\u00e1ch a \u017eil\u00e1ch s pomal\u00fdm pr\u016ftokem krve.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Bu\u0148ky pot\u00e9 produkovaly ciz\u00ed protein \u2013 spike protein nebo jak\u00fdkoli jin\u00fd protein. Imunitn\u00ed syst\u00e9m tyto bu\u0148ky napadl, co\u017e vedlo k tromb\u00f3ze a ucp\u00e1n\u00ed. Oligodendrocyty z\u00e1sobovan\u00e9 t\u011bmito c\u00e9vami odum\u00edraly a jejich myelinov\u00e9 pochvy se odlupovaly.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Dal\u0161\u00ed krok v jeho hypot\u00e9ze: <\/span><strong><span dir=\"auto\">Odpadaj\u00edc\u00ed kousky myelinu samy o sob\u011b uvedou do pohybu n\u011bco, co proces udr\u017euje v chodu.<\/span><\/strong><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Bhakdi se odvol\u00e1val na sv\u00e9 za\u010d\u00e1tky v Max Planckov\u011b institutu v roce 1972. Vysv\u011btlil, \u017ee v krvi existuj\u00ed dva kask\u00e1dov\u00e9 syst\u00e9my: koagulace a syst\u00e9m komplementu. Ten druh\u00fd generuje \u201eoh\u0148ostroj\u201c \u2013 z\u00e1n\u011bt. Bu\u0148ky obsahuj\u00ed ochrann\u00e9 proteiny, kter\u00e9 funguj\u00ed jako hasic\u00ed p\u0159\u00edstroje a neust\u00e1l\u00fdm mal\u00fdm aktivac\u00edm komplementu br\u00e1n\u00ed v tvorb\u011b neust\u00e1l\u00fdch bun\u011bk. P\u0159i sepsi \u2013 vyvolan\u00e9 endotoxiny \u2013 samotn\u00fd objem komplementu syst\u00e9m zahlt\u00ed.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">N\u011bkter\u00e9 protil\u00e1tky \u2013 nap\u0159\u00edklad p\u0159i transfuzn\u00edch reakc\u00edch nebo autoimunitn\u00edch onemocn\u011bn\u00edch \u2013 nebo bakteri\u00e1ln\u00ed l\u00e1tky, jako je endotoxin, aktivuj\u00ed komplement p\u0159\u00edmo v bu\u0148ce.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Bhakdi tvrd\u00ed, \u017ee p\u0159esn\u011b to se d\u011bje s <\/span><strong><span dir=\"auto\">lipidov\u00fdmi nano\u010d\u00e1sticemi ve vakc\u00edn\u00e1ch<\/span><\/strong><span dir=\"auto\"> . Tyto um\u011bl\u00e9 lipidy aktivuj\u00ed imunitn\u00ed syst\u00e9m nez\u00e1visle na protil\u00e1tk\u00e1ch. To m\u011blo okam\u017eit\u011b zastavit o\u010dkovac\u00ed kampa\u0148, ale nezastavilo se tak.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Asi p\u0159ed 20 lety bylo zji\u0161t\u011bno, \u017ee jeden typ bun\u011bk nese obzvl\u00e1\u0161t\u011b m\u00e1lo t\u011bchto ochrann\u00fdch molekul: <\/span><strong><span dir=\"auto\">oligodendrocyty<\/span><\/strong><span dir=\"auto\"> . Jsou proto extr\u00e9mn\u011b citliv\u00e9 na aktivaci komplementu ve sv\u00e9m okol\u00ed.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Exploze p\u0159\u00edmo postihuj\u00ed nejbli\u017e\u0161\u00ed oligodendrocyty. Vytv\u00e1\u0159\u00ed se tak za\u010darovan\u00fd kruh, kter\u00fd pokra\u010duje v cel\u00e9m nervov\u00e9m syst\u00e9mu. Podle jeho n\u00e1zoru to tak\u00e9 vysv\u011btluje, pro\u010d klasick\u00e1 demyeliniza\u010dn\u00ed a degenerativn\u00ed neurologick\u00e1 onemocn\u011bn\u00ed ne\u00faprosn\u011b postupuj\u00ed.<\/span><\/p>\n<h2 class=\"wp-block-heading\"><span dir=\"auto\">Kurkumin jako mo\u017en\u00fd inhibitor \u2013 prvn\u00ed anekdoty<\/span><\/h2>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Bhakdi hledal l\u00e1tky, kter\u00e9 potla\u010duj\u00ed aktivaci komplementu. Narazil na p\u0159\u00edrodn\u00ed l\u00e1tky, zejm\u00e9na <\/span><strong><span dir=\"auto\">na kurkumin<\/span><\/strong><span dir=\"auto\"> (v p\u0159episu \u201eKirkamin\u201c\/\u201eKurkumin\u201c).<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Je zn\u00e1m\u00fd sv\u00fdmi protiz\u00e1n\u011btliv\u00fdmi vlastnostmi, ale v\u011bt\u0161ina l\u00e9ka\u0159\u016f si nen\u00ed v\u011bdoma jeho souvislosti s komplementov\u00fdm syst\u00e9mem \u2013 t\u00e9matu, kter\u00e9 se na l\u00e9ka\u0159sk\u00e9 fakult\u011b prob\u00edr\u00e1 jen z\u0159\u00eddka.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">18. srpna 2026 to prezentoval na setk\u00e1n\u00ed \u201eL\u00e9ka\u0159\u016f pro etiku COVIDu\u201c. N\u00e1sleduj\u00edc\u00ed den mu norsk\u00fd kolega napsal: L\u00e9\u010dil pacienty s t\u011b\u017ek\u00fdmi zran\u011bn\u00edmi zp\u016fsoben\u00fdmi o\u010dkov\u00e1n\u00edm kurkuminem ji\u017e l\u00e9ta bez v\u00fdrazn\u00e9ho \u00fasp\u011bchu. Pak na\u0161el patentovan\u00fd n\u011bmeck\u00fd produkt, kter\u00fd dosahoval podstatn\u011b vy\u0161\u0161\u00edch hladin v krvi. Vzhledem k tomu, \u017ee hematoencefalick\u00e1 bari\u00e9ra byla u t\u011bchto pacient\u016f \u010dasto otev\u0159en\u00e1, l\u00e1tka se dostala do mozku. Posledn\u00ed dva nebo t\u0159i pacienti se subjektivn\u011b zlep\u0161ili.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Bhakdi koupil p\u0159\u00edpravek pro t\u0159i v\u00e1\u017en\u011b nemocn\u00e9 p\u0159\u00e1tele. O t\u0159i t\u00fddny pozd\u011bji, v pond\u011bl\u00ed p\u0159ed p\u0159edn\u00e1\u0161kou, mu zavolala kamar\u00e1dka jm\u00e9nem Katja. Byla \u010dty\u0159i roky upout\u00e1na na l\u016f\u017eko, m\u011bla dv\u011b dosp\u00edvaj\u00edc\u00ed d\u011bti a byla \u201ezcela uzav\u0159en\u00e1\u201c. Te\u010f c\u00edtila, \u017ee j\u00ed to d\u011bl\u00e1 dob\u0159e.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Bhakdi ozn\u00e1mil, \u017ee pr\u00e1v\u011b tento p\u0159\u00edb\u011bh vypr\u00e1v\u00ed tuto ned\u011bli.<\/span><\/p>\n<h2 class=\"wp-block-heading\"><span dir=\"auto\">Z\u00e1v\u011br: Hypot\u00e9za, nikoli dogma<\/span><\/h2>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Bhakdi to shrnul: P\u0159edlo\u017eil hypot\u00e9zu <\/span><strong><span dir=\"auto\">,<\/span><\/strong><span dir=\"auto\"> kter\u00e1 \u2013 pokud bude spr\u00e1vn\u00e1 \u2013 by mohla b\u00fdt v budoucnu u\u017eite\u010dn\u00e1. Byla zalo\u017eena na \u201eskute\u010dn\u00e9 v\u011bd\u011b\u201c, f\u00e9nixovi z popela Corony a \u201efale\u0161n\u00e9 v\u011bd\u011b\u201c.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Vyzval publikum, aby se ujalo ot\u011b\u017e\u00ed, hledalo pravdu a ze v\u0161ech sil se pokusilo hypot\u00e9zu vyvr\u00e1tit.<\/span><\/p>\n<p class=\"wp-block-paragraph\"><span dir=\"auto\">Do t\u00e9 doby by m\u011bl slou\u017eit jako maj\u00e1k nad\u011bje pro ty, kter\u00fdch se to t\u00fdk\u00e1. UK Column by se m\u011bl st\u00e1t \u201echr\u00e1mem soumraku\u201c a m\u00edstem vzk\u0159\u00ed\u0161en\u00ed pro opravdovou v\u011bdu.<\/span><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-1185\" src=\"http:\/\/www.infokuryr.cz\/n\/wp-content\/uploads\/2021\/04\/kuryr-podpis.png\" alt=\"\" width=\"84\" height=\"24\" \/><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Na oslav\u00e1ch 20. v\u00fdro\u010d\u00ed UK Column profesor Sucharit Bhakdi poprv\u00e9 ve\u0159ejn\u011b p\u0159edstavil hypot\u00e9zu, kter\u00e1 nazna\u010duje,&#8230;<\/p>\n","protected":false},"author":2,"featured_media":116751,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[1042,23,694,651,21],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/116750"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=116750"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/116750\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/116751"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=116750"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=116750"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=116750"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}