{"id":113438,"date":"2026-08-18T00:12:01","date_gmt":"2026-08-17T22:12:01","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=113438"},"modified":"2026-08-17T08:53:29","modified_gmt":"2026-08-17T06:53:29","slug":"vakcinovy-kartel-se-zoufale-drzi-nove-vakciny-mmr","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2026\/08\/18\/vakcinovy-kartel-se-zoufale-drzi-nove-vakciny-mmr\/","title":{"rendered":"Vakc\u00ednov\u00fd kartel se zoufale dr\u017e\u00ed nov\u00e9 vakc\u00edny MMR"},"content":{"rendered":"
<\/div>\n
\n
\n

Studie o autismu a \u201eneexistenci korelace\u201c m\u00e1 zna\u010dn\u00e9 nedostatky<\/span><\/strong><\/h3>\n

\u017d\u00e1dn\u00e1 skute\u010dn\u011b neo\u010dkovan\u00e1 kontroln\u00ed skupina, \u017e\u00e1dn\u00e1 klinick\u00e1 diagn\u00f3za autismu, \u017e\u00e1dn\u00e9 rodi\u010dovsk\u00e9 pr\u016fzkumy, \u017e\u00e1dn\u00e9 nez\u00e1visl\u00e9 p\u0159ezkoum\u00e1n\u00ed o\u010dkovac\u00edch z\u00e1znam\u016f a \u00fazce definovan\u00e1 definice autismu zalo\u017een\u00e1 na k\u00f3dov\u00e1n\u00ed MKN.<\/span><\/strong><\/p>\n

Nov\u00e1\u00a0<\/span>studie v \u010dasopise \u201ePediatric Infectious Disease Journal\u201c<\/span><\/a><\/em><\/strong>\u00a0je prezentov\u00e1na<\/span><\/a>\u00a0masm\u00e9dii ovl\u00e1dan\u00fdmi farmaceutick\u00fdm pr\u016fmyslem jako rozs\u00e1hl\u00e1 anal\u00fdza 2,56 milionu d\u011bt\u00ed\u00a0, kter\u00e1 vyvrac\u00ed souvislost mezi o\u010dkov\u00e1n\u00edm MMR vakc\u00ednou a autismem, ale celou pr\u00e1ci podkop\u00e1vaj\u00ed z\u00e1va\u017en\u00e9 metodologick\u00e9 probl\u00e9my.<\/span><\/p>\n

Nebyla pou\u017eita \u017e\u00e1dn\u00e1 skute\u010dn\u011b neo\u010dkovan\u00e1 kontroln\u00ed skupina, autismus nebyl klinicky diagnostikov\u00e1n, rodi\u010de nebyli dotazov\u00e1ni, o\u010dkovac\u00ed historie nebyla nez\u00e1visle ov\u011b\u0159ena a byla pou\u017eita \u00fazk\u00e1 definice autismu zalo\u017een\u00e1 na k\u00f3dech MKN.<\/span><\/strong><\/p>\n

\"Vakc\u00ednov\u00fd<\/figure>\n

\u017d\u00e1dn\u00e1 skute\u010dn\u00e1 kontroln\u00ed skupina bez o\u010dkov\u00e1n\u00ed<\/span><\/strong><\/h3>\n

Nejd\u016fle\u017eit\u011bj\u0161\u00ed je,\u00a0<\/span>\u017ee neexistovala \u017e\u00e1dn\u00e1 skute\u010dn\u00e1 kontroln\u00ed skupina bez o\u010dkov\u00e1n\u00ed<\/span><\/strong>\u00a0. Srovn\u00e1vac\u00ed d\u011bti byly jednodu\u0161e ty, u kter\u00fdch nebylo b\u011bhem relevantn\u00edho analyzovan\u00e9ho obdob\u00ed zdokumentov\u00e1no \u017e\u00e1dn\u00e9 o\u010dkov\u00e1n\u00ed MMR vakc\u00ednou. Nebyly nutn\u011b dosud o\u010dkov\u00e1ny a mohly dostat jin\u00e1 b\u011b\u017en\u00e1 d\u011btsk\u00e1 o\u010dkov\u00e1n\u00ed. Samotn\u00e1 studie uv\u00e1d\u00ed, \u017ee 62,1 % celkov\u00e9 kohorty dostalo posiluj\u00edc\u00ed d\u00e1vku PCV.<\/span><\/p>\n

Ani jejich\u00a0<\/span>status MMR vakc\u00edny nebyl nez\u00e1visle ov\u011b\u0159en<\/span><\/strong>\u00a0. Informace o statusu o\u010dkov\u00e1n\u00ed byly odvozeny z datov\u00fdch sad Epic, v\u010detn\u011b historicky zdokumentovan\u00fdch d\u00e1vek, bez potvrzen\u00ed ze strany vl\u00e1dn\u00edch registr\u016f o\u010dkov\u00e1n\u00ed, rodi\u010dovsk\u00fdch pr\u016fzkum\u016f nebo extern\u00ed kontroly dokumentace. To znamen\u00e1, \u017ee n\u011bkter\u00e9 d\u011bti uveden\u00e9 v datov\u00e9 sad\u011b jako \u201eneo\u010dkovan\u00e9\u201c mohly teoreticky dostat vakc\u00ednu MMR mimo z\u00fa\u010dastn\u011bn\u00fd syst\u00e9m Epic\/Cosmos, ani\u017e by tato d\u00e1vka byla zaznamen\u00e1na.<\/span><\/p>\n

Autismus byl zalo\u017een na k\u00f3dech MKN, nikoli na klinick\u00e9m hodnocen\u00ed<\/span><\/strong><\/h3>\n

Studie se op\u00edrala v\u00fdhradn\u011b o elektronick\u00e9 zdravotn\u00ed z\u00e1znamy. Autismus byl definov\u00e1n pomoc\u00ed k\u00f3du l\u00e9\u010dby F84.0 podle MKN-10, nikoli prost\u0159ednictv\u00edm nez\u00e1visl\u00e9ho klinick\u00e9ho posouzen\u00ed, test\u016f ADOS, kontroly z\u00e1znam\u016f nebo pohovor\u016f s rodi\u010di. T\u00e9m\u011b\u0159 9 % p\u0159\u00edpad\u016f autismu m\u011blo s touto diagn\u00f3zou pouze jednu sch\u016fzku. Informace o o\u010dkov\u00e1n\u00ed byly tak\u00e9 z\u00edsk\u00e1ny ze z\u00e1znam\u016f Epic bez jak\u00e9hokoli hl\u00e1\u0161en\u00e9ho ov\u011b\u0159en\u00ed oproti vl\u00e1dn\u00edm registr\u016fm, potvrzen\u00ed rodi\u010d\u016f nebo extern\u00ed kontroly z\u00e1znam\u016f.<\/span><\/p>\n

V\u00fdzkumn\u00edci zva\u017eovali pouze\u00a0<\/span>k\u00f3d MKN-10 F84.0, \u201eD\u011btsk\u00fd autismus\u201c, co\u017e je relativn\u011b \u00fazk\u00fd diagnostick\u00fd k\u00f3d<\/span><\/strong>\u00a0, sp\u00ed\u0161e ne\u017e \u0161ir\u0161\u00ed \u0161k\u00e1lu diagn\u00f3z autistick\u00e9ho spektra zahrnut\u00fdch pod F84.\u00a0N\u00e1rodn\u00ed referen\u010dn\u00ed hodnota 3,2 %, kterou uvedli,\u00a0<\/span>v\u0161ak odr\u00e1\u017e\u00ed tuto \u0161ir\u0161\u00ed definici autistick\u00e9ho spektra. To znamen\u00e1, \u017ee jejich prevalence autismu 2,55 %\u00a0<\/span><\/em>nen\u00ed p\u0159\u00edmo srovnateln\u00e1<\/span><\/strong>\u00a0s n\u00e1rodn\u00ed hodnotou 3,2 % a m\u016f\u017ee p\u0159ehl\u00ed\u017eet d\u011bti k\u00f3dovan\u00e9 v jin\u00fdch kategori\u00edch autistick\u00e9ho spektra. Auto\u0159i sami toto omezen\u00ed uzn\u00e1vaj\u00ed a uv\u00e1d\u011bj\u00ed, \u017ee budouc\u00ed studie by m\u011bly zkoumat cel\u00e9 spektrum F84.<\/span><\/p>\n

V\u00fdznamn\u00e9 metodologick\u00e9 nesrovnalosti<\/span><\/strong><\/h3>\n

Dopl\u0148kov\u00fd dodatek z\u0159ejm\u011b definuje diabetes u matky pomoc\u00ed\u00a0<\/span>k\u00f3du O23.*<\/span><\/strong>\u00a0, zat\u00edmco k\u00f3d O23.* se sou\u010dasn\u011b pou\u017e\u00edv\u00e1 pro infekce urogenit\u00e1ln\u00edho traktu b\u011bhem t\u011bhotenstv\u00ed. Toto je t\u0159eba objasnit, proto\u017ee by se mohlo jednat bu\u010f o typografickou chybu, nebo o potenci\u00e1ln\u00ed chybu v k\u00f3dov\u00e1n\u00ed v hlavn\u00ed anal\u00fdze. Pohlav\u00ed je tak\u00e9 uvedeno jako matouc\u00ed faktor v DAG studie, ale v uveden\u00e9m prim\u00e1rn\u00edm adjusta\u010dn\u00edm modelu chyb\u00ed.<\/span><\/p>\n

Na\u0161e komplexn\u00ed studie autismu odhaluje v\u011bt\u0161\u00ed probl\u00e9m<\/span><\/strong><\/h3>\n

Tuto \u00fazce zam\u011b\u0159enou anal\u00fdzu, vztahuj\u00edc\u00ed se v\u00fdhradn\u011b k vakc\u00edn\u011b MMR, je nutn\u00e9 zv\u00e1\u017eit i v kontextu mnohem \u0161ir\u0161\u00ed d\u016fkazn\u00ed z\u00e1kladny. V na\u0161\u00ed ned\u00e1vno publikovan\u00e9 pr\u00e1ci\u00a0<\/span>*Determinanty poruchy autistick\u00e9ho spektra*<\/span><\/a><\/strong>\u00a0jsme vyhodnotili 136 studi\u00ed, kter\u00e9 se zab\u00fdvaly vakc\u00ednami pro d\u011bti nebo jejich slo\u017ekami. Z nich 29 uv\u00e1d\u011blo neutr\u00e1ln\u00ed v\u00fdsledky, zat\u00edmco\u00a0<\/span>107 prezentovalo v\u00fdsledky, kter\u00e9 byly interpretov\u00e1ny jako nazna\u010duj\u00edc\u00ed mo\u017enou souvislost s poruchami autistick\u00e9ho spektra nebo jin\u00fdmi neurov\u00fdvojov\u00fdmi poruchami<\/span><\/strong>\u00a0\u2013 na z\u00e1klad\u011b epidemiologick\u00fdch, klinick\u00fdch, mechanistick\u00fdch, neuropatologick\u00fdch a kazuistick\u00fdch \u00fadaj\u016f.<\/span><\/p>\n

\"\"<\/figure>\n

Nejd\u016fle\u017eit\u011bj\u0161\u00ed je, \u017ee jsme\u00a0<\/span>identifikovali 12 studi\u00ed, kter\u00e9 skute\u010dn\u011b porovn\u00e1valy o\u010dkovan\u00e9 d\u011bti s d\u011btmi zcela neo\u010dkovan\u00fdmi<\/span><\/strong>\u00a0. Tyto studie konzistentn\u011b prokazovaly lep\u0161\u00ed celkov\u00e9 zdravotn\u00ed v\u00fdsledky u neo\u010dkovan\u00fdch kohort, v\u010detn\u011b ni\u017e\u0161\u00edho rizika chronick\u00fdch a neuropsychiatrick\u00fdch poruch, jako je autismus.<\/span><\/p>\n

To je z\u00e1kladn\u00ed probl\u00e9m studi\u00ed, jako je tato nov\u00e1 publikace o MMR vakc\u00edn\u011b: opakovan\u011b porovn\u00e1vaj\u00ed jednu vakc\u00ednu s d\u011btmi, kter\u00e9 dostaly jin\u00e9 vakc\u00edny, a pot\u00e9 prezentuj\u00ed v\u00fdsledek jako d\u016fkaz proti obecn\u011bj\u0161\u00ed souvislosti mezi o\u010dkov\u00e1n\u00edm a autismem. Dosud \u017e\u00e1dn\u00e1 studie neposoudila kumulativn\u00ed bezpe\u010dnost cel\u00e9ho o\u010dkovac\u00edho sch\u00e9matu d\u011bt\u00ed s ohledem na neurologick\u00fd v\u00fdvoj v pozd\u011bj\u0161\u00edm d\u011btstv\u00ed. Na z\u00e1klad\u011b sou\u010dasn\u00fdch znalost\u00ed z\u016fst\u00e1v\u00e1 o\u010dkov\u00e1n\u00ed d\u011bt\u00ed v\u00fdznamn\u00fdm rizikov\u00fdm faktorem pro poruchy autistick\u00e9ho spektra.<\/span><\/p>\n

Od Nicolase Hulschera, MPH<\/span><\/em><\/strong><\/p>\n<\/div>\n<\/div>\n

\n
\n

Zdroj<\/span><\/a><\/span><\/h3>\n

 <\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Studie o autismu a \u201eneexistenci korelace\u201c m\u00e1 zna\u010dn\u00e9 nedostatky \u017d\u00e1dn\u00e1 skute\u010dn\u011b neo\u010dkovan\u00e1 kontroln\u00ed skupina, \u017e\u00e1dn\u00e1…<\/p>\n","protected":false},"author":2,"featured_media":100470,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[729,11422,651,21],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/113438"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=113438"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/113438\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/100470"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=113438"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=113438"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=113438"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}