{"id":112147,"date":"2026-08-02T00:22:30","date_gmt":"2026-08-01T22:22:30","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=112147"},"modified":"2026-08-01T09:53:03","modified_gmt":"2026-08-01T07:53:03","slug":"vedci-objevili-rostlinnou-latku-s-potencialem-dramaticky-zlepsit-lecbu-revmatoidni-artritidy","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2026\/08\/02\/vedci-objevili-rostlinnou-latku-s-potencialem-dramaticky-zlepsit-lecbu-revmatoidni-artritidy\/","title":{"rendered":"V\u011bdci objevili rostlinnou l\u00e1tku s potenci\u00e1lem dramaticky zlep\u0161it l\u00e9\u010dbu revmatoidn\u00ed artritidy"},"content":{"rendered":"
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Bolest, otekl\u00e9 prsty a rann\u00ed ztuhlost kloub\u016f dok\u00e1\u017eou lidem s revmatoidn\u00ed artritidou v\u00fdrazn\u011b zkomplikovat ka\u017edodenn\u00ed \u017eivot.<\/span><\/strong><\/p>\n

Onemocn\u011bn\u00ed postupn\u011b po\u0161kozuje klouby a bez v\u010dasn\u00e9 l\u00e9\u010dby m\u016f\u017ee v\u00e9st k trval\u00e9mu omezen\u00ed pohybu i zhor\u0161en\u00ed kvality \u017eivota. Postihuje p\u0159ibli\u017en\u011b 1 % populace a navzdory pokrok\u016fm medic\u00edny zat\u00edm neexistuje zp\u016fsob, jak jej zcela vyl\u00e9\u010dit<\/span><\/p>\n

Dne\u0161n\u00ed l\u00e9\u010dba se op\u00edr\u00e1 zejm\u00e9na o protiz\u00e1n\u011btliv\u00e9 l\u00e9ky, kortikosteroidy a takzvan\u00e9 nemoc modifikuj\u00edc\u00ed l\u00e9ky v\u010detn\u011b biologick\u00e9 l\u00e9\u010dby. Mnoha pacient\u016fm p\u0159in\u00e1\u0161\u00ed v\u00fdraznou \u00falevu, ale ne v\u017edy dok\u00e1\u017ee onemocn\u011bn\u00ed zastavit a p\u0159i dlouhodob\u00e9m u\u017e\u00edv\u00e1n\u00ed m\u016f\u017ee b\u00fdt spojena s ne\u017e\u00e1douc\u00edmi \u00fa\u010dinky.<\/span><\/p>\n

Pr\u00e1v\u011b proto v\u011bdci hledaj\u00ed nov\u00e9 p\u0159\u00edstupy, kter\u00e9 by nebyly zam\u011b\u0159eny jen na tlumen\u00ed z\u00e1n\u011btu, ale zas\u00e1hly by samotn\u00e9 mechanismy onemocn\u011bn\u00ed. Pozornost v\u011bdc\u016f tentokr\u00e1t upoutala p\u0159\u00edrodn\u00ed slou\u010denina izolovan\u00e1 z k\u016fry stromu\u00a0<\/span>Phellodendron amurense<\/span><\/strong>\u00a0, kter\u00fd se ji\u017e stalet\u00ed vyu\u017e\u00edv\u00e1 v tradi\u010dn\u00ed asijsk\u00e9 medic\u00edn\u011b.<\/span><\/p>\n

Nejde v\u0161ak o b\u011b\u017en\u011b dostupn\u00fd dopln\u011bk stravy ani o l\u00e1tku, kterou by bylo mo\u017en\u00e9 snadno z\u00edskat u\u017e\u00edv\u00e1n\u00edm t\u00e9to rostliny. Ve v\u00fdzkumu v\u011bdci pracovali s jej\u00ed purifikovanou formou.<\/span><\/p>\n

Nov\u00e1 studie publikovan\u00e1 v \u010dasopise\u00a0<\/span>Engineering<\/span><\/em>\u00a0nazna\u010duje, \u017ee by mohla tlumit z\u00e1n\u011bt, chr\u00e1nit klouby a z\u00e1rove\u0148 ovliv\u0148ovat procesy, kter\u00e9 stoj\u00ed p\u0159i vzniku revmatoidn\u00ed artritidy.<\/span><\/p>\n

Co uk\u00e1zala studie<\/span><\/h2>\n

V\u00fdzkumn\u00edci zkoumali \u00fa\u010dinky t\u00e9to p\u0159\u00edrodn\u00ed slou\u010deniny na potkanech s experiment\u00e1ln\u011b vyvolanou revmatoidn\u00ed artritidou. Zv\u00ed\u0159ata dost\u00e1vala r\u016fzn\u00e9 d\u00e1vky po dobu 21 dn\u016f.<\/span><\/p>\n

Ve srovn\u00e1n\u00ed s nel\u00e9\u010den\u00fdmi zv\u00ed\u0159aty m\u011bli men\u0161\u00ed otok kloub\u016f, slab\u0161\u00ed z\u00e1n\u011bt a m\u00e9n\u011b po\u0161kozenou chrupavku i synovi\u00e1ln\u00ed membr\u00e1nu \u2013 jemnou v\u00fdstelku vyst\u00fdlaj\u00edc\u00ed vnit\u0159ek kloub\u016f.<\/span><\/p>\n

Krevn\u00ed testy z\u00e1rove\u0148 uk\u00e1zaly pokles n\u011bkolika ukazatel\u016f z\u00e1n\u011btu a p\u0159\u00edzniv\u00e9 zm\u011bny v \u010dinnosti imunitn\u00edho syst\u00e9mu. \u010c\u00e1st bun\u011bk podporuj\u00edc\u00edch z\u00e1n\u011bt ustoupila, zat\u00edmco p\u0159ibyly bu\u0148ky, kter\u00e9 pom\u00e1haj\u00ed z\u00e1n\u011bt tlumit a podporuj\u00ed obnovu po\u0161kozen\u00fdch tk\u00e1n\u00ed.<\/span><\/p>\n

Pro\u010d v\u00fdsledky v\u011bdc\u016f p\u0159ekvapily<\/span><\/h2>\n

Nejv\u011bt\u0161\u00edm p\u0159ekvapen\u00edm nebylo samotn\u00e9 zm\u00edrn\u011bn\u00ed z\u00e1n\u011btu. Mnohem zaj\u00edmav\u011bj\u0161\u00ed bylo, \u017ee zkouman\u00e1 slou\u010denina zas\u00e1hla n\u011bkolik proces\u016f, kter\u00e9 se na onemocn\u011bn\u00ed pod\u00edlej\u00ed sou\u010dasn\u011b. Pr\u00e1v\u011b takov\u00fd \u00fa\u010dinek je p\u0159i v\u00fdvoji nov\u00fdch l\u00e9k\u016f pom\u011brn\u011b vz\u00e1cn\u00fd.<\/span><\/p>\n

V\u011bdci zjistili, \u017ee revmatoidn\u00ed artritida v\u00fdrazn\u011b naru\u0161uje metabolismus mastn\u00fdch kyselin, kter\u00e9 pom\u00e1haj\u00ed regulovat z\u00e1n\u011btliv\u00e9 procesy. Zkouman\u00e1 l\u00e1tka dok\u00e1zala \u010d\u00e1st t\u011bchto zm\u011bn zvr\u00e1tit a obnovit p\u0159irozen\u011bj\u0161\u00ed fungov\u00e1n\u00ed bun\u011bk.<\/span><\/p>\n

Krom\u011b toho zpomalila nadm\u011brn\u00e9 mno\u017een\u00ed bun\u011bk synovi\u00e1ln\u00ed membr\u00e1ny, kter\u00e9 p\u0159isp\u00edvaj\u00ed k ni\u010den\u00ed kloub\u016f, podpo\u0159ila p\u0159irozen\u00e9 odstra\u0148ov\u00e1n\u00ed po\u0161kozen\u00fdch bun\u011bk a omezila tvorbu z\u00e1n\u011btliv\u00fdch l\u00e1tek.<\/span><\/p>\n

Podle autor\u016f p\u016fsob\u00ed tak\u00e9 na d\u016fle\u017eitou b\u00edlkovinu zapojenou do regulace metabolismu tuk\u016f a z\u00e1n\u011btu. Pr\u00e1v\u011b tento mechanismus by mohl vysv\u011btlovat, pro\u010d ovlivnila najednou n\u011bkolik proces\u016f souvisej\u00edc\u00edch s revmatoidn\u00ed artritidou.<\/span><\/p>\n

\u201eNa\u0161e v\u00fdsledky poskytuj\u00ed p\u0159edklinick\u00e9 d\u016fkazy, \u017ee tato slou\u010denina by mohla p\u0159edstavovat perspektivn\u00ed z\u00e1klad pro v\u00fdvoj nov\u00e9 l\u00e9\u010dby revmatoidn\u00ed artritidy,\u201c<\/span><\/em>\u00a0uvedli auto\u0159i studie.<\/span><\/p>\n

Co tyto v\u00fdsledky znamenaj\u00ed<\/span><\/h2>\n

V\u00fdsledky nazna\u010duj\u00ed, \u017ee zkouman\u00e1 l\u00e1tka nemus\u00ed p\u016fsobit pouze na zm\u00edrn\u011bn\u00ed p\u0159\u00edznak\u016f, ale m\u016f\u017ee ovliv\u0148ovat i n\u011bkter\u00e9 procesy, kter\u00e9 onemocn\u011bn\u00ed poh\u00e1n\u011bj\u00ed. Pr\u00e1v\u011b proto ji v\u011bdci pova\u017euj\u00ed za zaj\u00edmav\u00e9ho kandid\u00e1ta pro dal\u0161\u00ed v\u00fdvoj l\u00e9k\u016f.<\/span><\/p>\n

Je v\u0161ak t\u0159eba zd\u016fraznit, \u017ee zat\u00edm jde o preklinick\u00fd v\u00fdzkum. V\u0161echny experimenty byly provedeny na laboratorn\u00edch potkanech a na izolovan\u00fdch bu\u0148k\u00e1ch. To znamen\u00e1, \u017ee \u00fa\u010dinnost ani bezpe\u010dnost u lid\u00ed zat\u00edm nebyla potvrzena.<\/span><\/p>\n

M\u016f\u017eete tuto l\u00e1tku u\u017e\u00edvat ji\u017e dnes?<\/span><\/h2>\n

Zat\u00edm ne. Zkouman\u00e1 slou\u010denina nen\u00ed schv\u00e1len\u00fdm l\u00e9kem ani b\u011b\u017en\u011b dostupn\u00fdm v\u00fd\u017eivov\u00fdm dopl\u0148kem. A\u010dkoli poch\u00e1z\u00ed z k\u016fry stromu\u00a0<\/span>Phellodendron amurense<\/span><\/em>\u00a0, \u00fa\u010dinky pozorovan\u00e9 ve studii se t\u00fdkaly purifikovan\u00e9 l\u00e1tky p\u0159ipraven\u00e9 pro v\u00fdzkumn\u00e9 \u00fa\u010dely.<\/span><\/p>\n

Zat\u00edmco v\u00fdzkum v\u00edce nepokro\u010d\u00ed, pacienti s revmatoidn\u00ed artritidou mohou k podpo\u0159e standardn\u00ed l\u00e9\u010dby vyu\u017e\u00edt nap\u0159\u00edklad:<\/span><\/p>\n