{"id":108597,"date":"2026-06-13T00:16:44","date_gmt":"2026-06-12T22:16:44","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=108597"},"modified":"2026-06-12T12:49:12","modified_gmt":"2026-06-12T10:49:12","slug":"studie-spolecnosti-pfizer-o-rsv-zemrely-dva-kojenci-zaloba-proti-vlade-usa","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2026\/06\/13\/studie-spolecnosti-pfizer-o-rsv-zemrely-dva-kojenci-zaloba-proti-vlade-usa\/","title":{"rendered":"Studie spole\u010dnosti Pfizer o RSV: Zem\u0159ely dva kojenci \u2013 \u017ealoba proti vl\u00e1d\u011b USA"},"content":{"rendered":"
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Rodiny dvou \u010derno\u0161sk\u00fdch kojenc\u016f, kter\u00e9 zem\u0159ely v 60. letech 20. stolet\u00ed b\u011bhem vl\u00e1dn\u00edch studi\u00ed vakc\u00edny proti RSV, podaly feder\u00e1ln\u00ed \u017ealobu, v n\u00ed\u017e tvrd\u00ed, \u017ee v\u011bdci za\u0159adili d\u011bti do studie bez v\u011bdom\u00ed nebo souhlasu rodi\u010d\u016f. \u017daloba rovn\u011b\u017e uv\u00e1d\u00ed, \u017ee vzorky tk\u00e1n\u00ed od zem\u0159el\u00fdch kojenc\u016f pozd\u011bji p\u0159isp\u011bly k v\u00fdvoji modern\u00edch vakc\u00edn proti RSV.<\/span><\/strong><\/em><\/p>\n

Rodiny dvou \u010derno\u0161sk\u00fdch kojenc\u016f, kter\u00e9 zem\u0159ely b\u011bhem experiment\u00e1ln\u00edho testov\u00e1n\u00ed vakc\u00edny proti RSV v 60. letech 20. stolet\u00ed, podaly feder\u00e1ln\u00ed \u017ealobu proti Spojen\u00fdm st\u00e1t\u016fm. Obvi\u0148uj\u00ed vl\u00e1dn\u00ed v\u00fdzkumn\u00edky z toho, \u017ee d\u011bti zahrnuli do nebezpe\u010dn\u00e9ho l\u00e9ka\u0159sk\u00e9ho experimentu bez v\u011bdom\u00ed a souhlasu jejich rodi\u010d\u016f, jak uvedl den\u00edk New York Times.<\/span><\/p>\n

\u017daloba podan\u00e1 22. kv\u011btna u americk\u00e9ho okresn\u00edho soudu pro District of Columbia obvi\u0148uje N\u00e1rodn\u00ed instituty zdrav\u00ed (NIH) a dal\u0161\u00ed v\u00fdzkumn\u00edky z toho, \u017ee v letech 1965 a 1966 podrobili des\u00edtky kojenc\u016f \u2013 v\u011bt\u0161inou nebo v\u0161echny z n\u00edzkop\u0159\u00edjmov\u00fdch \u010derno\u0161sk\u00fdch rodin \u2013 test\u016fm s experiment\u00e1ln\u00ed vakc\u00ednou \u201eLot 100\u201c spole\u010dnosti Pfizer proti respira\u010dn\u00edmu syncyci\u00e1ln\u00edmu viru (RSV).<\/span><\/p>\n

Dva kojenci, Victor Marcellus King a Ross Otto Hambrick, pozd\u011bji zem\u0159eli na t\u011b\u017ek\u00e9 respira\u010dn\u00ed onemocn\u011bn\u00ed zp\u016fsoben\u00e9 vakc\u00ednou (VAERD, Vaccine-Associated Enhanced Respiratory Disease – Zhor\u0161en\u00e9 respira\u010dn\u00ed onemocn\u011bn\u00ed spojen\u00e9 s vakc\u00ednou).<\/span><\/p>\n

K VAERD doch\u00e1z\u00ed, kdy\u017e je o\u010dkovan\u00e9 d\u00edt\u011b, kter\u00e9 nikdy nem\u011blo RSV, vystaveno viru a rozvine se u n\u011bj z\u00e1va\u017en\u011bj\u0161\u00ed p\u0159\u00edpad RSV, ne\u017e by tomu bylo, kdyby vakc\u00ednu nedostalo.<\/span><\/p>\n

\u017dalobu podali Sharlette Hambrick a Darius King, kte\u0159\u00ed jednali jako z\u00e1stupci poz\u016fstalost\u00ed sv\u00fdch zesnul\u00fdch bratr\u016f. Tvrd\u00ed, \u017ee feder\u00e1ln\u00ed v\u00fdzkumn\u00edci nez\u00edskali souhlas rodi\u010d\u016f d\u011bt\u00ed, zatajili kl\u00ed\u010dov\u00e9 informace o p\u0159edchoz\u00edch selh\u00e1n\u00edch vakc\u00edn a pokra\u010dovali v klinick\u00e9m hodnocen\u00ed navzdory rostouc\u00edm d\u016fkaz\u016fm o tom, \u017ee vakc\u00edna u \u00fa\u010dastn\u00edk\u016f zp\u016fsobovala z\u00e1va\u017en\u00e9 ne\u017e\u00e1douc\u00ed \u00fa\u010dinky.<\/span><\/p>\n

\u017daloba rovn\u011b\u017e tvrd\u00ed, \u017ee vzorky tk\u00e1n\u00ed zem\u0159el\u00fdch d\u011bt\u00ed byly pozd\u011bji pou\u017eity k v\u00fdvoji vakc\u00edn proti RSV a vakc\u00edn s monoklon\u00e1ln\u00edmi protil\u00e1tkami, kter\u00e9 byly schv\u00e1leny v posledn\u00edch letech, co\u017e farmaceutick\u00fdm spole\u010dnostem p\u0159ineslo finan\u010dn\u00ed zisk.<\/span><\/p>\n

\u201eL\u00e9ka\u0159sk\u00fd v\u00fdzkum ve Spojen\u00fdch st\u00e1tech m\u00e1 dlouhou a problematickou historii, pokud jde o rasismus,\u201c uv\u00e1d\u00ed se v \u017ealob\u011b a srovn\u00e1v\u00e1 se s \u00fadajn\u00fdm chov\u00e1n\u00edm dal\u0161\u00ed nechvaln\u011b zn\u00e1m\u00fdmi p\u0159\u00edklady neetick\u00fdch experiment\u016f na Afroameri\u010danech, v\u010detn\u011b studie syfilisu v Tuskegee a zneu\u017e\u00edv\u00e1n\u00ed Henrietty Lacksov\u00e9.<\/span><\/p>\n

Rodiny kojenc\u016f nev\u011bd\u011bly, \u017ee d\u011bti byly podrobeny experimentu, dokud je v roce 2023 nekontaktoval report\u00e9r \u010dasopisu \u201eUndark\u201c v r\u00e1mci sv\u00e9ho v\u00fdzkumu pro tento \u010dl\u00e1nek.<\/span><\/p>\n

Report\u00e9r na\u0161el jm\u00e9na miminek ve vl\u00e1dou vydan\u00e9m laboratorn\u00edm z\u00e1pisn\u00edku l\u00e9ka\u0159e a dal\u0161\u00edch dokumentech z klinick\u00e9 studie, uvedl den\u00edk Times.<\/span><\/p>\n

Rodi\u010de nebyli informov\u00e1ni o tom, \u017ee se jejich d\u011bti \u00fa\u010dastn\u00ed studie experiment\u00e1ln\u00ed vakc\u00edny.<\/span><\/strong><\/p>\n

Na za\u010d\u00e1tku 60. let 20. stolet\u00ed vyvinuli v\u011bdci z NIH experiment\u00e1ln\u00ed vakc\u00ednu proti RSV metodou podobnou t\u00e9, kter\u00e1 byla pou\u017eita k v\u00fdvoji vakc\u00edny proti obrn\u011b. Vakc\u00ednu podali v\u00edce ne\u017e 50 d\u011btem v nemocnici zn\u00e1m\u00e9 p\u0159ev\u00e1\u017en\u011b \u010derno\u0161skou populac\u00ed pacient\u016f.<\/span><\/p>\n

T\u00e9m\u011b\u0159 polovina d\u011bt\u00ed se nakazila RSV a 10 z nich muselo b\u00fdt hospitalizov\u00e1no \u2013 co\u017e pozd\u011bji p\u0159ipustil v\u00fdzkumn\u00edk NIH Dr. Robert Chanock, kter\u00fd studii vedl, \u017ee je \u201emo\u017en\u00e1 mimo norm\u00e1ln\u00ed rozmez\u00ed\u201c.<\/span><\/p>\n

Podle \u017ealoby se v\u011bdci m\u00edsto opu\u0161t\u011bn\u00ed programu spojili se spole\u010dnost\u00ed Pfizer, aby vyvinuli koncentrovan\u011bj\u0161\u00ed verzi vakc\u00edny, kter\u00e1 se stala zn\u00e1mou jako \u201eLot 100\u201c.<\/span><\/p>\n

Spole\u010dnost Pfizer testovala \u201e\u0161ar\u017ei 100\u201c na \u010dty\u0159ech my\u0161\u00edch, \u010dty\u0159ech mor\u010datech a 25 opic\u00edch \u2013 a n\u00e1sledn\u011b dosp\u011bla k z\u00e1v\u011bru, \u017ee je dostate\u010dn\u011b bezpe\u010dn\u00e1 pro testov\u00e1n\u00ed na kojentech.<\/span><\/p>\n

V zim\u011b 1965\/66 v\u011bdci vybrali 31 nejmlad\u0161\u00edch d\u011bt\u00ed z jedn\u00e9 z nemocni\u010dn\u00edch klinik. Mezi vybran\u00fdmi kojenci byli podle \u017ealoby Victor King a Ross Hambrick ve v\u011bku 4, respektive 2 m\u011bs\u00edc\u016f \u2013 nejmlad\u0161\u00ed d\u011bti ve studii.<\/span><\/p>\n

Rodiny nebyly informov\u00e1ny ani o tom, \u017ee se d\u011bti \u00fa\u010dastn\u00ed studie, ani o p\u0159edchoz\u00ed ne\u00fasp\u011b\u0161n\u00e9 studii nebo rizic\u00edch spojen\u00fdch s o\u010dkov\u00e1n\u00edm.<\/span><\/p>\n

D\u011bti dostaly t\u0159i d\u00e1vky vakc\u00edny. Pod\u00e1v\u00e1n\u00ed pokra\u010dovalo i v dob\u011b, kdy musely b\u00fdt d\u011bti ze studie hospitalizov\u00e1ny, uv\u00e1d\u00ed se v \u017ealob\u011b.<\/span><\/p>\n

Miminka zem\u0159ela jen n\u011bkolik dn\u00ed pot\u00e9, co nemocnice studii ukon\u010dila.<\/span><\/strong><\/p>\n

B\u011bhem vypuknut\u00ed RSV ve Washingtonu koncem roku 1966 oba kojenci v\u00e1\u017en\u011b onemocn\u011bli.<\/span><\/p>\n

Victor King byl p\u0159ijat do nemocnice 30. prosince 1966 s t\u011b\u017ek\u00fdmi d\u00fdchac\u00edmi pot\u00ed\u017eemi. Zem\u0159el 1. ledna 1967. Ross Hambrick byl p\u0159ijat do nemocnice ve stejn\u00fd den a podle \u017ealoby zem\u0159el 2. ledna 1967.<\/span><\/p>\n

\u0158editel nemocnice se rozhodl studii ukon\u010dit 29. prosince, jen n\u011bkolik dn\u00ed p\u0159ed smrt\u00ed d\u011bt\u00ed. \u201eV t\u00e9 dob\u011b u\u017e bylo pro Victora a Rosse Ottov\u00fdch p\u0159\u00edli\u0161 pozd\u011b,\u201c uv\u00e1d\u00ed se v \u017ealob\u011b.<\/span><\/p>\n

\u0158editel nemocnice 3. ledna zaslal NIH dopis s d\u016fkazy o tom, \u017ee o\u010dkov\u00e1n\u00ed d\u011bti zhor\u0161ilo, nikoliv zhor\u0161ilo. Uvedl tak\u00e9, \u017ee v\u00fdsledky byly \u201ezcela neo\u010dek\u00e1van\u00e9\u201c, p\u0159esto\u017ee p\u0159edchoz\u00ed studie nazna\u010dovaly, \u017ee vakc\u00edna proti RSV m\u016f\u017ee zp\u016fsobit onemocn\u011bn\u00ed zp\u016fsoben\u00e9 varixy a varixy.<\/span><\/p>\n

Pitvy \u00fadajn\u011b odhalily, \u017ee ob\u011b d\u011bti m\u011bly t\u011b\u017ek\u00fd z\u00e1pal plic, infekci RSV a bakteri\u00e1ln\u00ed z\u00e1pal plic.<\/span><\/p>\n

V \u017ealob\u011b se uv\u00e1d\u00ed, \u017ee k v\u00fdvoji dne\u0161n\u00edch vakc\u00edn proti RSV byly pou\u017eity vzorky tk\u00e1n\u00ed od zem\u0159el\u00fdch kojenc\u016f.<\/span><\/strong><\/p>\n

Ne\u00fasp\u011bch studie Lot 100 zastavil v\u00fdvoj vakc\u00edn proti RSV na cel\u00e1 desetilet\u00ed.<\/span><\/p>\n

V\u011bdci pozd\u011bji pou\u017eili uchovan\u00e9 vzorky tk\u00e1n\u00ed zesnul\u00fdch d\u011bt\u00ed k prozkoum\u00e1n\u00ed, pro\u010d vakc\u00edna vedla k tak zni\u010duj\u00edc\u00edm v\u00fdsledk\u016fm, co\u017e by podle nich mohlo p\u0159isp\u011bt k v\u00fdvoji \u00fa\u010dinn\u00e9 vakc\u00edny proti RSV.<\/span><\/p>\n

Zkoum\u00e1n\u00ed vzork\u016f pomoc\u00ed nov\u00fdch technologi\u00ed v n\u00e1sleduj\u00edc\u00edch desetilet\u00edch pomohlo v\u011bdc\u016fm ur\u010dit, \u017ee vakc\u00edna zm\u011bnila strukturu d\u016fle\u017eit\u00e9ho proteinu RSV, zn\u00e1m\u00e9ho jako protein F, co\u017e zp\u016fsobilo, \u017ee imunitn\u00ed syst\u00e9m o\u010dkovan\u00fdch jedinc\u016f reagoval abnorm\u00e1ln\u011b, kdy\u017e byli p\u0159irozen\u011b vystaveni viru.<\/span><\/p>\n

\u017dalobci tvrd\u00ed, \u017ee tato zji\u0161t\u011bn\u00ed nakonec p\u0159isp\u011bla k v\u00fdvoji modern\u00edch vakc\u00edn proti RSV a protil\u00e1tkov\u00fdch terapi\u00ed, kter\u00e9 byly schv\u00e1leny americk\u00fdm \u00da\u0159adem pro kontrolu potravin a l\u00e9\u010div (FDA) v roce 2023.<\/span><\/p>\n

Americk\u00e9 ministerstvo spravedlnosti na \u017e\u00e1dost o koment\u00e1\u0159 k \u017ealob\u011b nereagovalo.<\/span><\/p>\n

Nov\u00e9 vakc\u00edny proti RSV by mohly p\u0159edstavovat stejn\u00e1 rizika, jak nazna\u010duj\u00ed d\u016fkazy.<\/span><\/strong><\/p>\n

V \u017ealob\u011b se uv\u00e1d\u00ed, \u017ee v\u00fdzkum proveden\u00fd na kojenc\u00edch umo\u017enil \u201ebezpe\u010dn\u00fd v\u00fdvoj\u201c jak vakc\u00edny proti RSV \u2013 kter\u00e1 byla poprv\u00e9 schv\u00e1lena pro dosp\u011bl\u00e9 nad 60 let v kv\u011btnu 2023 \u2013 tak i vakc\u00edn s monoklon\u00e1ln\u00edmi protil\u00e1tkami od spole\u010dnost\u00ed AstraZeneca a Sanofi pro kojence, kter\u00e9 byly schv\u00e1leny v \u010dervenci 2023.<\/span><\/p>\n

Spole\u010dnost Pfizer v sou\u010dasn\u00e9 dob\u011b vyr\u00e1b\u00ed p\u0159\u00edpravek Abrysvo, kter\u00fd je schv\u00e1len pro dosp\u011bl\u00e9 ve v\u011bku 60 let a star\u0161\u00ed, mlad\u0161\u00ed dosp\u011bl\u00e9 s vysok\u00fdm rizikem a t\u011bhotn\u00e9 \u017eeny.<\/span><\/p>\n

Spole\u010dnost GSK vyr\u00e1b\u00ed vakc\u00ednu Arexvy, schv\u00e1lenou pro dosp\u011bl\u00e9 ve v\u011bku 60 let a star\u0161\u00ed a vysoce rizikov\u00e9 dosp\u011bl\u00e9 ve v\u011bku 18 a\u017e 59 let. Spole\u010dnost Moderna vyr\u00e1b\u00ed vakc\u00ednu mResvia, mRNA vakc\u00ednu schv\u00e1lenou pro vysoce rizikov\u00e9 dosp\u011bl\u00e9 ve v\u011bku 60 let a star\u0161\u00ed a vysoce rizikov\u00e9 dosp\u011bl\u00e9 ve v\u011bku 18 a\u017e 59 let.<\/span><\/p>\n

Data z klinick\u00fdch studi\u00ed a anal\u00fdz po uveden\u00ed na trh v\u0161ak ukazuj\u00ed, \u017ee tyto schv\u00e1len\u00e9 l\u00e9\u010debn\u00e9 postupy mohou m\u00edt stejn\u00e9 bezpe\u010dnostn\u00ed probl\u00e9my jako p\u016fvodn\u00ed vakc\u00edny, krom\u011b jin\u00fdch.<\/span><\/p>\n

V roce 2024 musela spole\u010dnost Moderna zastavit klinick\u00e9 studie sv\u00e9 vakc\u00edny proti RSV pro kojence, kter\u00e1 z\u00edskala zrychlen\u00e9 schv\u00e1len\u00ed od FDA, pot\u00e9, co bylo zji\u0161t\u011bno, \u017ee vakc\u00edna pravd\u011bpodobn\u011b vede k vy\u0161\u0161\u00ed m\u00ed\u0159e z\u00e1va\u017en\u00e9ho onemocn\u011bn\u00ed RSV u o\u010dkovan\u00fdch kojenc\u016f. Jin\u00fdmi slovy, stejn\u00fd probl\u00e9m, jak\u00fd se vyskytoval u p\u016fvodn\u00edch vakc\u00edn ze 60. let.<\/span><\/p>\n

Ve stejn\u00e9m roce analyzovala francouzsk\u00e1 v\u011bdkyn\u011b Dr. H\u00e9l\u00e8ne Banounov\u00e1 v\u00fdsledky o\u010dkovac\u00ed kampan\u011b proti RSV v letech 2023\u20132024 ve \u010dty\u0159ech zem\u00edch. Ve Francii pozorovala \u201ev\u00fdznamn\u00fd n\u00e1r\u016fst \u00famrtnosti\u201c u novorozenc\u016f ve v\u011bku 2 a\u017e 6 dn\u016f, co\u017e nazna\u010duje, \u017ee VAERD by mohl b\u00fdt probl\u00e9mem i s monoklon\u00e1ln\u00edmi protil\u00e1tkami.<\/span><\/p>\n

Vakc\u00edny od spole\u010dnost\u00ed GSK a Pfizer c\u00edl\u00ed na protein F, kter\u00fd byl identifikov\u00e1n anal\u00fdzou d\u0159\u00edv\u011bj\u0161\u00edch studi\u00ed.<\/span><\/p>\n

Spole\u010dnost GSK zastavila klinick\u00e9 studie u t\u011bhotn\u00fdch \u017een pot\u00e9, co byla zji\u0161t\u011bna souvislost mezi vakc\u00ednou a p\u0159ed\u010dasn\u00fdmi porody. Zv\u00fd\u0161en\u00fd v\u00fdskyt p\u0159ed\u010dasn\u00fdch porod\u016f byl hl\u00e1\u0161en tak\u00e9 u o\u010dkovan\u00fdch \u017een pou\u017e\u00edvaj\u00edc\u00edch vakc\u00ednu Pfizer, ale podle v\u00fdrobce nebyly tyto \u00fadaje statisticky v\u00fdznamn\u00e9.<\/span><\/p>\n

Studie po schv\u00e1len\u00ed tak\u00e9 spojily vakc\u00ednu spole\u010dnosti Pfizer s p\u0159ed\u010dasn\u00fdmi porody, preeklampsi\u00ed a dal\u0161\u00edmi hypertenzn\u00edmi t\u011bhotensk\u00fdmi poruchami.<\/span><\/p>\n

Mezi rostouc\u00edm mno\u017estv\u00edm d\u016fkaz\u016f o ne\u017e\u00e1douc\u00edch \u00fa\u010dinc\u00edch spojen\u00fdch s vakc\u00ednou proti RSV je zdokumentovan\u00e9 riziko Guillain-Barr\u00e9ova syndromu.<\/span><\/p>\n

Tato zji\u0161t\u011bn\u00ed vedla Centra pro kontrolu a prevenci nemoc\u00ed (CDC) v \u010dervnu 2024 ke sta\u017een\u00ed sv\u00fdch doporu\u010den\u00ed a omezen\u00ed doporu\u010den\u00e9 v\u011bkov\u00e9 skupiny pro o\u010dkov\u00e1n\u00ed proti RSV z dosp\u011bl\u00fdch ve v\u011bku 60 let a star\u0161\u00edch na dosp\u011bl\u00e9 ve v\u011bku 75 let a star\u0161\u00ed \u2013 p\u0159esto\u017ee FDA schv\u00e1lila vakc\u00ednu pro dosp\u011bl\u00e9 mlad\u0161\u00ed 75 let.<\/span><\/p>\n

Od Brendy Baletti, Ph.D.<\/span><\/em><\/strong><\/p>\n<\/div>\n<\/div>\n

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Zdroj<\/span><\/a><\/span><\/h3>\n

 <\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Rodiny dvou \u010derno\u0161sk\u00fdch kojenc\u016f, kter\u00e9 zem\u0159ely v 60. letech 20. stolet\u00ed b\u011bhem vl\u00e1dn\u00edch studi\u00ed vakc\u00edny…<\/p>\n","protected":false},"author":2,"featured_media":108598,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[245,315,46,422],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/108597"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=108597"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/108597\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/108598"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=108597"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=108597"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=108597"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}