{"id":108206,"date":"2026-06-07T00:15:19","date_gmt":"2026-06-06T22:15:19","guid":{"rendered":"https:\/\/www.infokuryr.cz\/n\/?p=108206"},"modified":"2026-06-04T13:28:35","modified_gmt":"2026-06-04T11:28:35","slug":"velka-analyza-zjistila-ze-leky-uzivane-desetitisici-lidi-s-cukrovkou-zpusobuji-ridnuti-a-krehnuti-kosti","status":"publish","type":"post","link":"https:\/\/www.infokuryr.cz\/n\/2026\/06\/07\/velka-analyza-zjistila-ze-leky-uzivane-desetitisici-lidi-s-cukrovkou-zpusobuji-ridnuti-a-krehnuti-kosti\/","title":{"rendered":"Velk\u00e1 anal\u00fdza zjistila, \u017ee l\u00e9ky u\u017e\u00edvan\u00e9 desetitis\u00edci lid\u00ed s cukrovkou zp\u016fsobuj\u00ed \u0159\u00eddnut\u00ed a k\u0159ehnut\u00ed kost\u00ed"},"content":{"rendered":"
<\/div>\n

V\u00edce ne\u017e ka\u017ed\u00fd osm\u00fd Ameri\u010dan v sou\u010dasnosti u\u017e\u00edv\u00e1 l\u00e9ky na cukrovku a obezitu zvan\u00e9 agonisty receptoru GLP-1, jako jsou Ozempic, Wegovy, Rybelsus a Mounjaro. I na Slovensku jejich prodej raketov\u011b stoup\u00e1 – meziro\u010dn\u011b se zdvojn\u00e1sobil, p\u0159i\u010dem\u017e v lo\u0148sk\u00e9m roce bylo spot\u0159ebov\u00e1no 366 tis\u00edc balen\u00ed.<\/span><\/strong><\/p>\n

Tyto l\u00e9ky p\u016fsob\u00ed tak, \u017ee udr\u017euj\u00ed hladinu cukru v krvi, potla\u010duj\u00ed chu\u0165 k j\u00eddlu, zpomaluj\u00ed vyprazd\u0148ov\u00e1n\u00ed \u017ealudku a sni\u017euj\u00ed objem j\u00eddla pot\u0159ebn\u00e9ho k zasycen\u00ed.<\/span><\/p>\n

Nov\u00fd v\u00fdzkum prezentovan\u00fd v b\u0159eznu 2026 na v\u00fdro\u010dn\u00edm setk\u00e1n\u00ed\u00a0<\/span>Americk\u00e9 akademie ortopedick\u00fdch chirurg\u016f<\/span><\/em>\u00a0v\u0161ak odhalil vzorec, o kter\u00e9m v\u011bt\u0161ina p\u0159edepisuj\u00edc\u00edch l\u00e9ka\u0159\u016f sv\u00e9 pacienty neinformuje.<\/span><\/p>\n

Tyto l\u00e9ky potichu ni\u010d\u00ed hustotu kost\u00ed rychlost\u00ed, kter\u00e1 by mohla podlomit zdrav\u00ed milion\u016f lid\u00ed, a to doslova.<\/span><\/p>\n

P\u011btilet\u00e1 anal\u00fdza v\u00edce ne\u017e 146 000 dosp\u011bl\u00fdch s obezitou a cukrovkou 2. typu zjistila, \u017ee u u\u017eivatel\u016f l\u00e9k\u016f GLP-1 je relativn\u00ed riziko rozvoje\u00a0<\/span>osteopor\u00f3zy<\/span><\/a>\u00a0o 29 % vy\u0161\u0161\u00ed ve srovn\u00e1n\u00ed s u\u017eivateli, zat\u00edmco riziko osteomalace (stavu zahrnuj\u00edc\u00edho m\u011bknut\u00ed kost\u00ed) se v\u00edce ne\u017e zdvojn\u00e1sob.<\/span><\/p>\n

Samostatn\u00e1 studie z \u00fanora 2026 v odborn\u00e9m \u010dasopise\u00a0<\/span>Journal of Clinical Endocrinology & Metabolism<\/span><\/em>\u00a0tato zji\u0161t\u011bn\u00ed potvrdila a uk\u00e1zala, \u017ee star\u0161\u00ed dosp\u011bl\u00ed u\u017e\u00edvaj\u00edc\u00ed l\u00e9ky GLP-1 \u010del\u00ed o 11% vy\u0161\u0161\u00edmu riziku zlomenin zp\u016fsoben\u00fdch k\u0159ehkost\u00ed kost\u00ed ve srovn\u00e1n\u00ed s t\u011bmi, kte\u0159\u00ed u\u017e\u00edvaj\u00ed jin\u00e9 l\u00e9ky.<\/span><\/p>\n

Co odhalily klinick\u00e9 \u00fadaje<\/span><\/h2>\n

Zji\u0161t\u011bn\u00ed z p\u011btilet\u00e9ho observa\u010dn\u00edho obdob\u00ed jsou podpo\u0159ena \u00fadaji z randomizovan\u00fdch kontrolovan\u00fdch studi\u00ed, kter\u00e9 p\u0159\u00edmo m\u011b\u0159ily zm\u011bny v kostech.<\/span><\/p>\n

Klinick\u00e1 studie f\u00e1ze 2 zjistila, \u017ee 52 t\u00fddn\u016f pod\u00e1v\u00e1n\u00ed l\u00e9ku s \u00fa\u010dinnou l\u00e1tkou semaglutid (l\u00e9ky Ozempic, Rybelsus a Wegovy) jednou t\u00fddn\u011b sn\u00ed\u017eilo miner\u00e1ln\u00ed hustotu ky\u010dle o 2,6% ve srovn\u00e1n\u00ed s placebem. Hustota bedern\u00ed p\u00e1te\u0159e klesla o 2,1%.<\/span><\/p>\n

B\u011bhem cel\u00e9 studie se markery resorpce kost\u00ed zv\u00fd\u0161ily, zat\u00edmco markery tvorby kost\u00ed to nekompenzovaly \u2013 co\u017e znamen\u00e1, \u017ee t\u011blo rozkl\u00e1dalo kosti rychleji, ne\u017e je dok\u00e1zalo obnovit.<\/span><\/p>\n

Tato zji\u0161t\u011bn\u00ed jsou v souladu s desetilet\u00edmi v\u00fdzkumu rychl\u00e9ho \u00fabytku hmotnosti. V\u00fdznamn\u00fd \u00fabytek hmotnosti p\u0159ibli\u017en\u011b o 7 a\u017e 10% prost\u0159ednictv\u00edm omezen\u00ed kalori\u00ed, se cvi\u010den\u00edm nebo bez n\u011bj, trvale vede k rychl\u00e9mu \u00fabytku kostn\u00ed hmoty.<\/span><\/p>\n

Bariatrick\u00e1 chirurgie (l\u00e9\u010dba obezity) m\u00e1 podobn\u00e9 \u00fa\u010dinky. L\u00e9ky s obsahem GLP-1 se vyzna\u010duj\u00ed jejich \u0161irok\u00fdm pou\u017e\u00edv\u00e1n\u00edm: p\u0159ibli\u017en\u011b 12% Ameri\u010dan\u016f v sou\u010dasnosti u\u017e\u00edv\u00e1 tyto l\u00e9ky a a\u017e 35% hl\u00e1s\u00ed z\u00e1jem o jejich u\u017e\u00edv\u00e1n\u00ed.<\/span><\/p>\n

Stovky milion\u016f lid\u00ed na cel\u00e9m sv\u011bt\u011b mohou b\u00fdt na cest\u011b ke zrychlen\u00e9mu \u00fabytku kostn\u00ed hmoty, p\u0159i\u010dem\u017e v\u011bt\u0161ina z nich neabsolvovala \u017e\u00e1dn\u00fd screening, \u017e\u00e1dn\u00e9 pokyny ohledn\u011b suplementace a \u017e\u00e1dnou diskusi o tom, jak hubnut\u00ed zp\u016fsoben\u00e9 l\u00e9ky ovliv\u0148uje kostru.<\/span><\/p>\n

Pro\u010d potla\u010den\u00ed chuti k j\u00eddlu oslabuje kostru<\/span><\/h2>\n

Mechanismus, kter\u00fd stoj\u00ed za rizikem \u0159\u00eddnut\u00ed kost\u00ed, nen\u00ed z\u00e1hadn\u00fd.<\/span><\/p>\n

Kdy\u017e dramaticky klesne chu\u0165 k j\u00eddlu, kles\u00e1 i p\u0159\u00edjem potravy as t\u00edmto poklesem kles\u00e1 i p\u0159\u00edjem v\u00e1pn\u00edku, vitam\u00ednu D, ho\u0159\u010d\u00edku a b\u00edlkovin, na kter\u00fdch je kostn\u00ed tk\u00e1\u0148 z\u00e1visl\u00e1 na udr\u017een\u00ed sv\u00e9 hustoty a opravu po\u0161kozen\u00ed bun\u011bk.<\/span><\/p>\n

Kost je dynamick\u00fd syst\u00e9m, kter\u00fd neust\u00e1le rozkl\u00e1d\u00e1 starou tk\u00e1\u0148 a obnovuje novou. Tento proces vy\u017eaduje st\u00e1l\u00fd p\u0159\u00edsun specifick\u00fdch \u017eivin, aby z\u016fstal v rovnov\u00e1ze. Kdy\u017e se p\u0159\u00edsun \u017eivin p\u0159eru\u0161\u00ed, rozpad kost\u00ed p\u0159ed\u010d\u00ed obnovu.<\/span><\/p>\n

\u00dabytek hmotnosti probl\u00e9m zhor\u0161uje, proto\u017ee kosti reaguj\u00ed na mechanickou z\u00e1t\u011b\u017e. Leh\u010d\u00ed t\u011bla kladou na kostru men\u0161\u00ed z\u00e1t\u011b\u017e a kostra reaguje sn\u00ed\u017een\u00edm sv\u00e9 hustoty. Ka\u017ed\u00fd ztracen\u00fd kilogram (co\u017e je jinak dobr\u00e1 v\u011bc) z\u00e1rove\u0148 sni\u017euje stimul, kter\u00fd mluv\u00ed kostn\u00edm bu\u0148k\u00e1m, aby si udr\u017eeli hmotu.<\/span><\/p>\n

Dr. Clifford Rosen, profesor medic\u00edny na Tuftsov\u011b univerzit\u011b, kter\u00fd studuje vliv l\u00e9k\u016f GLP-1 na zdrav\u00ed kost\u00ed, poznamenal, \u017ee \u00fast\u0159edn\u00ed ot\u00e1zkou je, zda jde o norm\u00e1ln\u00ed kompenzaci kostry nebo o rychlej\u0161\u00ed \u00fabytek kostn\u00ed hmoty, ne\u017e se o\u010dek\u00e1valo.<\/span><\/p>\n

Tento historick\u00fd kontext je d\u016fle\u017eit\u00fd, proto\u017ee i d\u0159\u00edv\u011bj\u0161\u00ed intervence na hubnut\u00ed \u2013 od fenfenu v 90. letech a\u017e po Atkinsonovu dietu \u2013 vyvol\u00e1valy obavy z vy\u010derp\u00e1n\u00ed \u017eivin.<\/span><\/p>\n

Uveden\u00e9 re\u017eimy v\u0161ak postihly mnohem m\u00e9n\u011b lid\u00ed. Nikdy p\u0159edt\u00edm neu\u017e\u00edval ka\u017ed\u00fd osm\u00fd \u010dlov\u011bk l\u00e9ky, kter\u00e9 sou\u010dasn\u011b potla\u010duj\u00ed chu\u0165 k j\u00eddlu a zp\u016fsobuj\u00ed rychl\u00e9 hubnut\u00ed, \u010d\u00edm\u017e vznikl popula\u010dn\u00ed experiment v oblasti zdrav\u00ed kost\u00ed, kter\u00fd nem\u00e1 obdoby.<\/span><\/p>\n

Kroky, kter\u00e9 by m\u011bl ka\u017ed\u00fd u\u017eivatel l\u00e9k\u016f GLP-1 podniknout co nejd\u0159\u00edve<\/span><\/h2>\n

V\u00e1pn\u00edk, vitamin D a b\u00edlkoviny se mus\u00ed st\u00e1t neoddiskutovateln\u00fdmi denn\u00edmi prioritami pro ka\u017ed\u00e9ho, kdo u\u017e\u00edv\u00e1 l\u00e9ky GLP-1. Jeliko\u017e potla\u010den\u00ed chuti k j\u00eddlu sni\u017euje p\u0159\u00edjem potravy, u\u017eivatel\u00e9 \u010del\u00ed re\u00e1ln\u00e9mu riziku poklesu pod prahov\u00e9 hodnoty \u017eivin pot\u0159ebn\u00e9 k udr\u017een\u00ed kost\u00ed.<\/span><\/p>\n

P\u0159\u00edjem v\u00e1pn\u00edku by m\u011bl dos\u00e1hnout 1000 a\u017e 1200 miligram\u016f denn\u011b. Hladina vitam\u00ednu D v krvi by se m\u011bla pohybovat mezi 40 a\u017e 60 ng\/ml. Tohoto c\u00edle v\u011bt\u0161ina lid\u00ed u\u017e\u00edvaj\u00edc\u00edch standardn\u00ed dopl\u0148ky nedos\u00e1hne bez testov\u00e1n\u00ed a p\u0159izp\u016fsobov\u00e1n\u00ed pod l\u00e9ka\u0159sk\u00fdm dohledem.<\/span><\/p>\n

P\u0159\u00edjem b\u00edlkovin v mno\u017estv\u00ed 1,2 a\u017e 1,6 gramu na kilogram t\u011blesn\u00e9 hmotnosti denn\u011b podporuje zachov\u00e1n\u00ed svalov\u00e9 hmoty i kolagenov\u00e9 matrice, kter\u00e1 zaji\u0161\u0165uje struktur\u00e1ln\u00ed integritu kost\u00ed.<\/span><\/p>\n

Cvi\u010den\u00ed s odporem by m\u011blo b\u00fdt pova\u017eov\u00e1no za nutnost, ne za voliteln\u00fd zvyk. Mechanick\u00e1 z\u00e1t\u011b\u017e je jedn\u00edm z nejsiln\u011bj\u0161\u00edch sign\u00e1l\u016f, kter\u00e9 t\u011blo pou\u017e\u00edv\u00e1 k udr\u017een\u00ed hustoty kost\u00ed.<\/span><\/p>\n

V\u00fdzkum opakovan\u011b potvrzuje, \u017ee cvi\u010den\u00ed s odporem zachov\u00e1v\u00e1 hustotu kostn\u00edch miner\u00e1l\u016f b\u011bhem hubnut\u00ed a kdy\u017e se l\u00e9ky GLP-1 kombinuj\u00ed se strukturovan\u00fdm cvi\u010den\u00edm, ztr\u00e1ta hustoty kost\u00ed se do zna\u010dn\u00e9 m\u00edry zm\u00edrn\u00ed.<\/span><\/p>\n

Dokonce i dv\u011b a\u017e t\u0159i tr\u00e9ninky s vlastn\u00ed v\u00e1hou nebo lehk\u00fdmi \u010dinkami t\u00fddn\u011b poskytuj\u00ed v\u00fdznamnou ochranu kostry.<\/span><\/p>\n

Je v\u0161ak t\u0159eba u\u017e\u00edvat v\u00edce v\u011bc\u00ed ne\u017e jen v\u00e1pn\u00edk. Ho\u0159\u010d\u00edk je pot\u0159ebn\u00fd pro vst\u0159eb\u00e1v\u00e1n\u00ed v\u00e1pn\u00edku a \u010dasto se vy\u010derp\u00e1v\u00e1 spolu s vitam\u00ednem D.\u00a0<\/span>Vitamin K2<\/span><\/a>\u00a0sm\u011b\u0159uje v\u00e1pn\u00edk do kostn\u00ed tk\u00e1n\u011b, a nikoli do arteri\u00e1ln\u00edch st\u011bn.<\/span><\/p>\n

V klinick\u00fdch studi\u00edch bylo prok\u00e1z\u00e1no, \u017ee suplementace kolagenov\u00fdmi peptidy m\u00e1 pozitivn\u00ed vliv na hustotu kostn\u00edch miner\u00e1l\u016f.<\/span><\/p>\n

Ponau\u010den\u00ed je zdokonalovat se, ne b\u00e1t se<\/span><\/h2>\n

Americk\u00fd\u00a0<\/span>\u00da\u0159ad pro kontrolu potravin a l\u00e9\u010div<\/span><\/em>\u00a0(FDA) ji\u017e v p\u00edsemn\u00e9 informaci pro u\u017eivatele l\u00e9k\u016f GLP-1 s \u00fa\u010dinnou l\u00e1tkou semaglutid uv\u00e1d\u00ed, \u017ee mohou zv\u00fd\u0161it riziko zlomenin u star\u0161\u00edch dosp\u011bl\u00fdch a \u017een.<\/span><\/p>\n

Navzdory rostouc\u00edmu po\u010dtu d\u016fkaz\u016f v\u0161ak \u00fa\u0159ad nena\u0159\u00eddil varov\u00e1n\u00ed p\u0159ed atrofi\u00ed sval\u016f nebo odbour\u00e1n\u00edm kost\u00ed.<\/span><\/p>\n

Dr. Christopher McGowan, gastroenterolog, kter\u00fd provozuje kliniku na hubnut\u00ed v Severn\u00ed Karol\u00edn\u011b, zd\u016fraz\u0148uje, \u017ee v\u00fdzkum by nem\u011bl zm\u011bnit p\u0159edepisov\u00e1n\u00ed l\u00e9k\u016f GLP-1, ale m\u011bl by slou\u017eit jako p\u0159ipom\u00ednka, \u017ee l\u00e9\u010dba cukrovky a obezity vy\u017eaduje tak\u00e9 pokyny t\u00fdkaj\u00edc\u00ed se p\u0159\u00edjmu b\u00edlkovin, cvi\u010den\u00ed a monitorov\u00e1n\u00ed zdrav\u00ed kost\u00ed.<\/span><\/p>\n

Jeho zhodnocen\u00ed je, \u017ee je t\u0159eba se ponau\u010dit, nem\u00edt strach a zdokonalit p\u00e9\u010di o sv\u00e9 zdrav\u00ed.<\/span><\/p>\n

P\u011bt let \u00fadaj\u016f potvrdilo to, co mechanismus v\u017edy nazna\u010doval. L\u00e9ky, kter\u00e9 potla\u010duj\u00ed chu\u0165 k j\u00eddlu a zp\u016fsobuj\u00ed rychl\u00e9 hubnut\u00ed, z\u00e1rove\u0148 sni\u017euj\u00ed p\u0159\u00edjem \u017eivin a mechanick\u00e9 podn\u011bty, kter\u00e9 kostn\u00ed tk\u00e1\u0148 pot\u0159ebuje k tomu, aby z\u016fstala siln\u00e1.<\/span><\/p>\n

Pro miliony lid\u00ed, kte\u0159\u00ed v sou\u010dasnosti u\u017e\u00edvaj\u00ed tyto l\u00e9ky, a pro miliony dal\u0161\u00edch, kte\u0159\u00ed je zva\u017euj\u00ed, \u010d\u00edslo na v\u00e1ze hovo\u0159\u00ed jen \u010d\u00e1st p\u0159\u00edb\u011bhu. To, co se d\u011bje s kostrou pod povrchem, z\u016fst\u00e1v\u00e1 nepozorov\u00e1no.<\/span><\/p>\n

Z\u00e1v\u011br<\/span><\/strong><\/h2>\n

O p\u0159\u00edrodn\u00ed l\u00e9\u010db\u011b cukrovky jsme p\u0159ed \u010dasem vydali tak\u00e9 samostatnou elektronickou knihu. V\u00edce informac\u00ed o n\u00ed naleznete\u00a0\u00a0<\/span>ZDE<\/span><\/strong><\/a>\u00a0\u00a0(o jej\u00ed \u010desk\u00e9 verzi\u00a0\u00a0<\/span>ZDE<\/span><\/strong><\/a>\u00a0).<\/span><\/p>\n

V e-knize se dozv\u00edte v\u0161e pot\u0159ebn\u00e9 pro l\u00e9\u010dbu diabetu 1. i 2. typu, v\u010detn\u011b p\u0159\u00ed\u010din onemocn\u011bn\u00ed, jak p\u0159edch\u00e1zet v\u00e1\u017en\u00fdm komplikac\u00edm typu slepota, amputace kon\u010detin \u010di selh\u00e1n\u00ed srdce nebo ledvin, jak se cukrovka l\u00e9\u010d\u00ed pomoc\u00ed stravy, dopl\u0148k\u016f stravy a bylinek, jak na ni ovliv\u0148uje \u017eivotn\u00ed styl a mnoho.<\/span><\/p>\n

Autor: Willow Tohi, Zdroj:\u00a0<\/span>naturalnews.com<\/span><\/a><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

V\u00edce ne\u017e ka\u017ed\u00fd osm\u00fd Ameri\u010dan v sou\u010dasnosti u\u017e\u00edv\u00e1 l\u00e9ky na cukrovku a obezitu zvan\u00e9 agonisty…<\/p>\n","protected":false},"author":2,"featured_media":108207,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[5355,5714,11092,839,21],"_links":{"self":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/108206"}],"collection":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/comments?post=108206"}],"version-history":[{"count":0,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/posts\/108206\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media\/108207"}],"wp:attachment":[{"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/media?parent=108206"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/categories?post=108206"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.infokuryr.cz\/n\/wp-json\/wp\/v2\/tags?post=108206"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}